NEXT :: how do I select the best PEEp during NIV? Silvia Coppola. It’s a holy grail question. But in spont breathing pts , effects on 1 effort. 2 respiratory muscles 3. Lung units. Etc #LIVES2022#ventilation@ESICM
High level of peep can make lung more homogeneous and reduce diaphragm stretch. pubmed.ncbi.nlm.nih.gov/27002273/ but there are 3 drawbacks 1. Neuro mechanical uncoupling
But also expiratory muscles recruitment and found increase in the activity of abdominal wall muscles and gastric pressure increases. 3. Drawback on “effort and drive”. Capturing all of this in total stress. #LIVES2022#ventilation@ESICM
Silvia Coppola - summarises all of the PEEP questions using mechanical power paradigm. High PEEP can have benefits but detrimental. Like anything In icm , what compromise would you accept ? #Ventilation#LIVES2022@ESICM
Luigi asking pertinent question :: “complex physiology is great but what about day to day NIV use and monitoring “? Silvia answers : P oes is the key. Without it we are in a dark in our clinical evaluation. #LIVES2022#ventilation@katinthelair@ESICM
Mariangela PELLEGRINI
Uppsala- Sweden
"Do we Need a biological definition of ARDS"
- Berlin definition has NO Diffuse alveolar damage .
- the Berlin defn does not capture well
Frohlich - different definitions specificity of 0.63, 0.42, 0.31 even! #ventilation#ards#LIVES2022
ARDS - new definition or phenotypes by @GicoBellani refreshing with Kigali definition of ARDS - useful not just low resource but during pandemic in supposedly high income settings and only draw back is no PEEp requirement #ards#ventilation#LIVES2022@ESICM
@GicoBellani@ESICM Resolved versus confirmed ARDS
- prospectively applying Berlin definition did work but if ya wait 24 hrs and re-measure P/F ratio, you end up stratifying much better.
- Better separation of groups
NEXT Speaker : VA ecmo for which patients?
Alain COMBES
Severe cardiogenic shock has different phenotypes 1. medical cardiogenic shock(AMI, end stage dilated CM, myocarditis, septic shock) 2. Post cardiotomy refractory CS (post CABG) #LIVES2022 @ESICM#ecmo#resuscitation#ALS
@ESICM 2022 what do the guidelines say
- ESC recommends short term MCS should be considred in cardiogenic shock.
IABP may be considered but not routinely recommended in post MI #LIVES2022