Lea Alhilali, MD Profile picture
Nov 4, 2022 15 tweets 8 min read Read on X
1/Hate it when one radiologist called the stenosis mild, the next one said moderate--but it was unchanged?!

Here’s a #tweetorial of a lumbar grading system that’s easy, reproducible & evidence-based

#medtwitter #spine #neurosurgery #radres #neurorad #meded #FOAMed #FOAMrad Image
2/Lumbar stenosis has always been controversial. In 2012, they tried to survey spine experts to come to a consensus as to what are the most important criteria for canal & foraminal stenosis. And the consensus was…that there was no consensus. So what should you use to call it? Image
3/Well, you don’t want just gestalt it—that is a recipe for inconsistency & disagreement. But you don’t want to measure everything either—measurements are not only cumbersome, they introduce reader variability & absolute measurements don’t mean the same thing in every patient. Image
4/Think of it functionally. Nerves need to fit in their space, like you fit in clothing. Mild stenosis is like comfy clothes—no squeezing. Moderate stenosis clothing isn’t loose, but there isn’t extra room either. Severe stenosis is like too tight jeans, your body gets compressed Image
5/So how do we tell if the nerves have enough room—if the clothing fits loosely, tight, or too tightly? We look at the space around them. For the canal, it is CSF—if there's enough room, extra space will be filled by CSF. For foramina, it is fat—extra room is filled by fat. Image
6/For mild canal stenosis, there is mild attenuation of the CSF space, but there is still plenty of CSF around, just like there is plenty of room in your comfy sweat pants Image
7/For moderate canal stenosis, the canal starts closing in, so there is less CSF around and the nerve roots appear aggregated. It’s like the clothes you wear to the club, there isn’t much room between your skin & the clothing, but you can still fit into them (hopefully) Image
8/Severe canal stenosis is the too tight jeans. The canal doesn’t just hug up to the nerve roots, it compresses them. Like your belly after a big meal trying to get into tight jeans, they get squished and deformed in order to fit, so they can’t be separated from each other. Image
9/This classification isn’t just easy to remember, it’s also evidence based. This is the Lee classification that has excellent reproducibility not just among radiologists, but among everyone. And it does correlate w/increasing symptoms. Image
10/For foraminal narrowing, the nerve inside the foramen has fat around it on four sides that can be attenuated as the space gets tighter. How many sides are attenuated determines how severe the stenosis is. Image
11/Mild stenosis is where you have loss of the fat on 2 sides. So it is still comfy clothing bc the fat is preserved on the other two sides, so you still have lots of space. Image
12/For moderate stenosis, you lose the space on all four sides, but the nerve itself is not compressed or deformed. Like a sleek outfit, it shows your curves, but doesn’t deform them. It’s not a comfy outfit, per se, & I wouldn’t eat a lot while wearing it, but it’s not too small Image
13/For severe stenosis, we are trying to fit into those jeans from high school and it isn’t going well. You are squishing in everything you can to get it to fit. Same with the foramen—the fat isn’t just gone, the nerve is compressed and deformed. Image
14/This is also named the Lee system. It fits well with the Lee classification for canal stenosis. It also is extremely reproducible and correlates with findings at surgery.

So you don’t have to remember a complicated system—just ask yourself, how does the clothing fit? Image
15/So put away your measuring calipers! You can end the inter-observer variability. These systems are easy to remember, make sense, and are based in evidence. As they say, if it fits—wear it! Image

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More from @teachplaygrub

May 17
1/ I always say, "Anyone can see the bright spot on diffusion images—what sets you apart is if you can tell them why it’s there!”

If you don't why a stroke happened, you can't prevent the next one!

Can YOU tell a stroke’s etiology from an MRI?

Here’s a thread to show you how! Image
2/First a review of the vascular territories.

I think the vascular territories look a butterfly—w/the ACA as the head/body, PCA as the butt/tail, and MCA territories spreading out like a butterfly wings. Image
3/Of course, it’s more complicated than that.

Medially, there are also small vessel territories—the lenticulostriates & anterior choroidal.

I think they look like little legs, coming out from between the ACA body & PCA tail. Image
Read 25 tweets
May 14
1/Got the diagnosis when it comes to vessel stenosis?

Or is your knowledge narrow when it comes to vessel narrowing?

When it comes to vasospasm, do you know why it happens or what to look for?

Here is the thread you NEED to unravel why vessels twist up! Image
2/Vasospasm results from subarachnoid hemorrhage (SAH) & a buildup of multiple factors

It’s like how you can handle 1 nag from your boss on Monday—but after nagging all week, you break down on Friday!

Same w/vasospasm—it doesn’t happen until the end of the week after SAH! Image
3/So what is nagging that causes the vessel to shut down?

When the body breaks down blood from SAH, it releases free heme

And this free heme causes a cascade of negative consequences, call heme-related inflammation

So free heme is the annoying boss! Image
Read 21 tweets
May 13
1/ “Now listen carefully!”

Everyone has so much fear about the anatomy where they hear!

Do you dread temporal bone anatomy?

Do find the understanding ossicles impossible?

Do you know the ice cream cone sign on CT & then nada?

Then you need this thread on ossicular anatomy! Image
2/For the middle ear, I have a rule of 3s.

Middle ear is divided into 3 parts & it contains 3 ossicles.

Today we will focus on the ossicles—each of which has 3 parts! Image
3/First ossicle you meet when you enter the middle ear is the malleus.

It’s called the malleus because it acts like a mallet that hits a drum—literally—the ear drum!

I think it looks like Dr. Evil’s mini me, with its short body and round bald head Image
Read 19 tweets
May 8
1/Asking “How old are you?” can be dicey—both in real life & on MRI!

Do you know how to tell the age of blood on MRI?

Here’s a thread on how to date blood on MRI!

After reading this, when you see a hemorrhage, your guess on its age will always be in the right vein! Image
2/If you ask someone how to date blood on MRI, they’ll spit out a crazy mnemonic about babies that tells you what signal blood should be on T1 & T2 imaging by age.

But mnemonics are crutch—they help you memorize, but not understand

If you understand, you don’t need to memorize Image
3/If you look at the mnemonic, you will notice one thing—the T1 signal is all you need to tell if blood is acute, subacute or chronic.

T2 signal will tell if it is early or late in each of those time periods—but that type of detail isn’t needed in real life

So let’s look at T1 Image
Read 21 tweets
May 3
1/Time to go with the flow!

Hoping no one notices you don’t know the anatomy of internal carotid (ICA)?

Do you say “carotid siphon” & hope no one asks for more detail?

Here’s a thread to help you siphon off some information about ICA anatomy! Image
2/ICA is like a staircase—winding up through important anatomic regions like a staircase winding up to each floor Lobby is the neck.

First floor is skullbase/carotid canal. Next it stops at the cavernous sinus, before finally reaching the rooftop balcony of the intradural space. Image
3/ICA is divided into numbered segments based on landmarks that denote transitions on its way up the floors.

C1 is in the lobby or neck.

You can remember this b/c the number 1 looks elongated & straight like a neck. Image
Read 10 tweets
Apr 25
1/Have some confusion about tumor perfusion?

Do you go into a coma looking at scans for glioma?

Never fear!

Read on for this month's @theAJNR SCANtastic for what you need to know on the latest in brain tumor imaging!

ajnr.org/content/45/4/4…
Image
@TheAJNR 2/Since the prehistoric days of medicine (1979!), we knew that some brain tumor patients treated w/radiation (XRT) initially declined, but then get better.

Today, we see this on imaging, where it looks worse early, but then gets better.

Now we call this pseudoprogression. Image
@TheAJNR 3/Why does this happen?

XRT induces a lot of inflammatory changes—from initiating the complement cascade to opening the blood brain barrier (BBB)

It’s these inflammatory changes that make the imaging look worse. Image
Read 21 tweets

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