Lea Alhilali, MD Profile picture
Nov 4, 2022 15 tweets 8 min read Read on X
1/Hate it when one radiologist called the stenosis mild, the next one said moderate--but it was unchanged?!

Here’s a #tweetorial of a lumbar grading system that’s easy, reproducible & evidence-based

#medtwitter #spine #neurosurgery #radres #neurorad #meded #FOAMed #FOAMrad Image
2/Lumbar stenosis has always been controversial. In 2012, they tried to survey spine experts to come to a consensus as to what are the most important criteria for canal & foraminal stenosis. And the consensus was…that there was no consensus. So what should you use to call it? Image
3/Well, you don’t want just gestalt it—that is a recipe for inconsistency & disagreement. But you don’t want to measure everything either—measurements are not only cumbersome, they introduce reader variability & absolute measurements don’t mean the same thing in every patient. Image
4/Think of it functionally. Nerves need to fit in their space, like you fit in clothing. Mild stenosis is like comfy clothes—no squeezing. Moderate stenosis clothing isn’t loose, but there isn’t extra room either. Severe stenosis is like too tight jeans, your body gets compressed Image
5/So how do we tell if the nerves have enough room—if the clothing fits loosely, tight, or too tightly? We look at the space around them. For the canal, it is CSF—if there's enough room, extra space will be filled by CSF. For foramina, it is fat—extra room is filled by fat. Image
6/For mild canal stenosis, there is mild attenuation of the CSF space, but there is still plenty of CSF around, just like there is plenty of room in your comfy sweat pants Image
7/For moderate canal stenosis, the canal starts closing in, so there is less CSF around and the nerve roots appear aggregated. It’s like the clothes you wear to the club, there isn’t much room between your skin & the clothing, but you can still fit into them (hopefully) Image
8/Severe canal stenosis is the too tight jeans. The canal doesn’t just hug up to the nerve roots, it compresses them. Like your belly after a big meal trying to get into tight jeans, they get squished and deformed in order to fit, so they can’t be separated from each other. Image
9/This classification isn’t just easy to remember, it’s also evidence based. This is the Lee classification that has excellent reproducibility not just among radiologists, but among everyone. And it does correlate w/increasing symptoms. Image
10/For foraminal narrowing, the nerve inside the foramen has fat around it on four sides that can be attenuated as the space gets tighter. How many sides are attenuated determines how severe the stenosis is. Image
11/Mild stenosis is where you have loss of the fat on 2 sides. So it is still comfy clothing bc the fat is preserved on the other two sides, so you still have lots of space. Image
12/For moderate stenosis, you lose the space on all four sides, but the nerve itself is not compressed or deformed. Like a sleek outfit, it shows your curves, but doesn’t deform them. It’s not a comfy outfit, per se, & I wouldn’t eat a lot while wearing it, but it’s not too small Image
13/For severe stenosis, we are trying to fit into those jeans from high school and it isn’t going well. You are squishing in everything you can to get it to fit. Same with the foramen—the fat isn’t just gone, the nerve is compressed and deformed. Image
14/This is also named the Lee system. It fits well with the Lee classification for canal stenosis. It also is extremely reproducible and correlates with findings at surgery.

So you don’t have to remember a complicated system—just ask yourself, how does the clothing fit? Image
15/So put away your measuring calipers! You can end the inter-observer variability. These systems are easy to remember, make sense, and are based in evidence. As they say, if it fits—wear it! Image

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More from @teachplaygrub

Apr 19
1/Having trouble remembering how to differentiate dementias on imaging?

Is looking at dementia PET scans one of your PET peeves?

Here’s a thread to show you how to remember the imaging findings in dementia & never forget! Image
2/The most common functional imaging used in dementia is FDG PET. And the most common dementia is Alzheimer’s disease (AD).

On PET, AD demonstrates a typical Nike swoosh pattern—with decreased metabolism in the parietal & temporal regions Image
3/The swoosh rapidly tapers anteriorly—& so does hypometabolism in AD in the temporal lobe. It usually spares the anterior temporal poles.

So in AD look for a rapidly tapering Nike swoosh, w/hypometabolism in the parietal/temporal regions—sparing the anterior temporal pole Image
Read 16 tweets
Apr 18
1/”That’s a ninja turtle looking at me!” I exclaimed.

My fellow rolled his eyes, “Why do I feel I’m going to see this on X or twitter soon…”

He was right!

A thread about one of my favorite imaging findings & pathology behind it ! Image
2/Now the ninja turtle isn’t an actual sign—yet!

But I am hoping to make it go viral as one.

To understand what this ninja turtle is, you first have to know the anatomy in this region.

I have always thought the medulla looks like a 3 leaf clover in this region. Image
3/ The most medial bump of the clover is the medullary pyramid (motor fibers).

Next to it is the inferior olivary nucleus (ION), & finally, the last largest leaf is the inferior cerebellar peduncle.

Now you can see that the ninja turtle eyes correspond to the ION. Image
Read 11 tweets
Apr 17
1/CSF leaks are controversial!

Some say they're overdiagnosed, others underdiagnosed

How can YOU make sure you aren’t under or overdiagnosing?

Are you BERN-ing to know when to suspect CSF leak?

Here’s a 🧵about the CSF leak Bern score so you don’t get BERN-ed by CSF leaks Image
2/In CSF leaks, everyone knows about brain sagging.

But this can happen w/other diseases, ie Chiari 1.

Other findings can be seen on brain MRI in CSF leaks.

But what are these findings & are some findings more suggestive than others?

Do⬆️findings = ⬆️suspicion? Image
3/The Bern group looked at 9 quantitative & 7 qualitative signs seen on brain MRI in CSF leaks to see which are most important.

Depending on type & # of findings, they developed a score to indicate what level of suspicion you should have for a leak. Image
Read 15 tweets
Apr 15
1/Is remembering cerebellar anatomy making you dizzy?

Need help telling your flocculus from your nodule?

How much cerebellar anatomy do YOU know?

Here’s some help w/an anatomy thread on the 9 lobules of the vermis! Image
2/Coming from anterior, the first lobule is the lingula

It sticks out from the front of the vermis & is connected to the superior cerebellar peduncle (SCP)

I remember this bc of its very appropriate name—lingula—it looks like a tongue sticking out of the vermis to lick the SCP Image
3/Moving clockwise, next is the central lobule

I remember this bc it's positioned exactly how a central lobule should be positioned, in the driver’s seat!

It's where the front driver position would be if the vermis was a car—up front, looking out a windshield over the lingula Image
Read 12 tweets
Apr 12
1/Time is brain! But what time is it?

If you don’t know the time of stroke onset, are you able to deduce it from imaging?

Here’s a thread to help you date a stroke on MRI! Image
2/In ~25% of acute stroke patients, the time of last known well is well, not known.

Then it’s important to use the stroke’s MR imaging features to help date its timing.

Is it hyperacute? Acute? Subacute? Or are the “stroke” symptoms from a seizure from their chronic infarct? Image
3/Strokes evolve, or grow old, the same way people evolve or grow old.

Appearance of stroke on imaging mirrors the life stages of a person—you just have to change days for a stroke into years for a person.

So 15 day old stroke has features of a 15 year old person, etc. Image
Read 22 tweets
Apr 1
1/Does your ability to remember temporal lobe anatomy seem, well, temporary?

Or are you feeling temporally challenged when it comes to this complex region?

Here’s a thread to help you remember the structures of the temporal lobe! Image
2/Temporal lobe can be divided centrally & peripherally.

Centrally is the hippocampus.

It’s a very old part of the brain & is relatively well preserved going all the way back to rats.

Its main function is memory—getting both rats & us through mazes—including the maze of life Image
3/Peripherally is the neocortex.

Although rats also have neocortex, theirs is much different structurally than humans.

So I like to think of neocortex as providing the newer (neo) functions of the temporal lobes seen in humans: speech, language, visual processing/social cues Image
Read 12 tweets

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