Acute Necrotizing Encephalitis (ANE) is a rare, but fatal complication of influenza infections in children. It presents with all the other symptoms of the flu, but also altered mental status and seizures (which may be difficult to initially distinguish from febrile seizures).
ANE leads to significant cerebral edema and can rapidly lead to cerebral herniation and death.
And for those that recover, less than 10% have complete neurologic recovery.
Image source: DOI:10.1093/cid/cit922
And before you ask, no this is not just something written about in case reports. I have personally taken care of patients with influenza ANE.
Just another reason you should get your influenza #vaccine#FluShot
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