1/ 🧵How much would you trust Harvard as a source of information as opposed to your family and friends?

Well, today, Harvard Medical School published an article as a part of its continuing coverage of COVID-19.

I would like to cite a few sentences.
2/ "Currently, published medical literature suggests that #LongCovid occurs in 5 to 80 percent of patients following an infection. The U.S. Centers for Disease Control and Prevention suggests that nearly one in five American adults who have had COVID-19 now have long COVID.
3/ A conservative estimate from the Brookings Institution suggests that #LongCovid may be keeping as many as 4 million Americans out of work.

#LongCOVID, considered a silent pandemic by many, is running parallel to the COVID-19 pandemic.
4/ Primary care offices across the United States are seeing patients with possible #LongCovid , who may experience #LongCovid symptoms anywhere from weeks to years after their original infection."

hms.harvard.edu/news/long-covi…
5/ I listen to what Harvard researchers say. I don´t know about you.

#LongCovid is a #MassDisablingEvent. Science denialism will not change anything about it.
6/ Available data suggest that reinfections with SARS-CoV-2 cumulatively increase the risk of developing #LongCovid.

Imho: The statistical bias of the sample is filtered out to a large extent by the same bias in the control group. The data is relevant.
7/ In fact, there are complete and logical theories behind it. You can read about them here. thetyee.ca/Analysis/2022/…
8/ The statements here have nothing to do with fearmongering. This is about considering what science teaches us.

Instead of turning away from science and living in self-denialism, my dream would be that people embrace science. All we would need to do is calmly act sensibly.
9/ Prevent infections. Oral vaccines will make it easier in the future.

But the solution is not vaccines alone. The solution would be "vaccines plus". A general striving for R < 1 within the limits of what is reasonably feasible. Until further notice.
10/ Here is an article to be shared with friends and family regarding the latest published study on how reinfections cumulatively add risk.

reuters.com/business/healt…

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More from @DyorsMathew

Nov 9
/ 🧵I. The two false binaries (“the double binary fallacy”) upon which public health responses to #SARSCoV2 mostly have been based on so far

This thread is part 1 of 7 of the mother thread #FreshStart2PublicDebate.
/ This subthread conjectures that public health responses have been relying on an overly simplistic understanding of immunity and of health, respectively.
/ Arguing black and white is of course almost always wrong. Health is not black and white. Immunity is not black and white.

However, people often argue that they have "had COVID-19" and seem to be done with the topic.
Read 10 tweets
Nov 9
/ 🧵A call for a fresh start to a public debate amidst an unfolding public health disaster

We need to discuss the future of public health.
/ A global public health disaster has been and still is haunting us. At best, learning from it will allow us to understand more about how to deal with the unfolding climate disaster.
/ This “mother thread” comprising seven subthreads is aimed at multiplicators who are invited to write their own story. Moreover, it is aimed at everyone for discussing, criticizing, supporting it, and for retweeting in order to facilitate a #FreshStart2PublicDebate.
Read 18 tweets
Nov 9
/ 🧵III. Why is immunity not “binary” (immune vs not immune against a pathogen)?

This thread is part 3 of 7 of the mother thread #FreshStart2PublicDebate.
/ Our immune system has two arms: the innate immune system and the adaptive immune system. The innate immune system is the first line of defense. It sends out the alarm that something is wrong. It generally recognizes patterns in cells that help sort self from pathogens.
/ For example, when an innate immune cell comes into contact with a bacteria cell, it identifies it as not self because bacteria have a cell wall structure that’s not found in human cells.
Read 46 tweets
Nov 9
/🧵II. Why is health not “binary” (alive vs. seriously sick / dead)?

This thread is part 2 of 7 of the mother thread #FreshStart2PublicDebate.

It is about a nuanced understanding of health in terms of a complex state and about the effect of SARS-CoV-2 infections.
/ The state of health involves, for example, the state of the microbiome and it is characterized by a degree of inflammation / oxidative stress, and it is defined along the spectrum of aging / senescence.
/ Here is for revisiting the risks associated with a #SARSCoV2 infection.

The risks can be approached by dividing the time span after an infection into three phases:

The acute phase after infection
The 12 week window post-infection phase
The long term phase (3 months +)
Read 134 tweets
Oct 14
1/ 🧵 on China’s oral vaccine

#ConvideciaAir

by CanSino Inc.

that received an emergency authorization in China.
2/ Booster vaccination with Convidecia Air (Ad5-nCoV) induced a superior T-cell response and neutralizing antibody responses compared to those induced by the homologous inactivated vaccine booster or heterologous recombinant protein vaccine booster.
3/ At day 7 after booster vaccination, intramuscular Ad5-nCoV induced an obvious IgG antibody response, but no IgG antibody response was found in the aerosolized Ad5-nCoV group, indicating that aerosolized Ad5-nCoV stimulated a slower systemic immune response .
Read 14 tweets
Oct 14
1/ 🧵Jetzt beginnt eine neue Welle.

Dass @Karl_Lauterbach am 8. Oktober 2022 nicht wusste, dass im November eine Welle (BQ1.1, XBB, ...) Deutschland treffen wird, darf man wohl getrost als unmöglich erachten.

2/ Es am 8.10 als eine zunehmende Unwahrscheinlichkeit zu bezeichnen, dass BA.5 die einzige Variante in der Zeit bis zum nächsten Sommer bleibt, war nicht ein scherzhafter Euphemismus.
3/ Damit bleiben zwei Optionen:

Es war
a) eine absichtliche Verzerrung der Realität; oder
b) die Frucht einer Selbsttäuschung.
Read 17 tweets

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