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Rheum Cat Profile picture
@rheum_cat
Nov 11, 2022 • 10 tweets • 7 min read • Read on X
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Dr John Pauling on Raynaud's

🔑Age of onset a major factor to differentiate primary vs secondary

Other etiologies to consider other than rheum conditions

#ACR22 #ReviewCourse Image
1* Raynaud's as a dx of exclusion (I know some people do not like this term), at least based on the criteria of LeRoy & Medsger (1992)

#ACR22 #ReviewCourse Image
🥶Studies about prevalence of RP & January temps

Studies showing a link between low BMI (in women) and RP

Perhaps I should be glad I don't have RP!

#ACR22
CV risk factors and 1* RP? Image
Considerations for 1* RP and possible underlying etiology

👉If low BMI: keep core body temp warm

👉If subclinical ATH/CV risk factors: smoking cessation if smokers

#ACR22 #Reviewcourse Image
2* Raynaud's - target mgmt

Iatrogenic here includes meds, like beta blockers

#ACR22 #Reviewcourse Image
How is the outcome measured in SSc Raynaud's trials?

a look into the symptom diary

#ACR22 #ReviewCourse Image
UK consensus guidelines for mgmt in SSc pubmed.ncbi.nlm.nih.gov/26116156/

Another expert opinion based algorithm: pubmed.ncbi.nlm.nih.gov/35382396/

#ACR22 #Reviewcourse ImageImage
How does all of this translate into clinical practice?

#ACR22 #ReviewCourse Image
RACAND: Raynaud's with anticentromere Ab and necrosis of the digits

pubmed.ncbi.nlm.nih.gov/11004618/

#ACR22 #ReviewCourse Image

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More from @rheum_cat

Rheum Cat Profile picture
Nov 13, 2022
#ACR22 social media talk, very meta
Part 1️⃣: optimize your conference tweeting
If you're reading this you probably know all of this!

The first pro-tip was figure out the conference hashtag
The second? Engage with others in rheum
#ACR22
What else?

👉amplify your group
👉amplify speakers and sessions of interest
👉amplify your colleagues so they will amplify you in turn

#ACR22
Read 10 tweets
Rheum Cat Profile picture
Nov 13, 2022
#ACR22 infection (COVID) posters Image
Abs 0784 @CCalabreseDO

Cleveland Clinic breakthrough infections, including data on n=21 who received Evusheld

📌Publication here: pubmed.ncbi.nlm.nih.gov/35791921/

#ACR22
@CCalabreseDO Abs 0779 @CCalabreseDO

Experience with evusheld PrEP with IMID on BCDT at Cleveland Clinic

📌Publication here: pubmed.ncbi.nlm.nih.gov/36123015/

#ACR22
Read 13 tweets
Rheum Cat Profile picture
Nov 13, 2022
#ACR22 #Feedback
The EULAR e posters were tiny (bad) but speakers could zoom in and out (good)

That would have been nice for #IgniteTalks #ACR22
The sound is adequate though. EULAR issue was that the sound was poor in their (smaller) poster tour stages #ACR22 #IgniteTalk
Read 4 tweets
Rheum Cat Profile picture
Nov 13, 2022
#ACR22 epidemiology posters Image
Abs 0700 @zach_wallace_md
💻Using NLP, ML algorithms to identify ANCA vasculitis cases

They also looked at the difference in performance metrics with/without filtering keywords

An explosion of NLP studies in rheum! #ACR22
@zach_wallace_md Abs 0732 Ho, et al. @JYazdanyMD @MilenaGianfran
💻Part of the explosion of NLP studies in rheum

Here the UCSF group aimed to capture VZV cases (differentiate from vaccination); and to capture active vs historical cases

See their diagrams explaining the steps!
#ACR22
Read 13 tweets
Rheum Cat Profile picture
Nov 13, 2022
We have learned quite quickly that a virtual ONLY poster hall mixed into a hybrid meeting doesn't work well.

Poor wifi and the crashing platform compound the problem

And if it's online ONLY, is that truly hybrid?

#ACR22
This is not a complaint thread. I am hoping we can have discussion about what works/doesn't work, and what could be done next year for #ACR23
It goes without saying that an in-person poster hall is the most requested item on the wishlist for #ACR23

@GrantSchulert @Tuhina_Neogi
Read 5 tweets
Rheum Cat Profile picture
Nov 13, 2022
Biostatician @MikeLaValley8 @BU_BMC_Rheum presents a quick overview on how to appropriately interpret results from studies #ACR22

Of course this is not an exhaustive deep dive, but covers some common errors of interpretation Image
@MikeLaValley8 @BU_BMC_Rheum First, what is your research question? What is the question you are trying to answer with t he study?

👉Does this exposure CAUSE this outcome?

#ACR22 Image
@MikeLaValley8 @BU_BMC_Rheum What are common observational study designs and what are big issues to watch out for?

These are issues that can affect the validity of their results.

There are more potential issues within these study designs that is beyond the scope of this table

#ACR22 Image
Read 15 tweets

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