Longish Thread 👇

Recently, the Uttarakhand State Government issued a ban and subsequently revoked its order prohibiting Patanjali Ayurved from manufacturing five products to treat blood pressure, diabeties, glaucoma and other diseases.

hindustantimes.com/india-news/utt…

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This punitive action was the result of a complaint filed by @drbabukv alleging violations of the Drugs and Magic Remedies Act by Patanjali Ayurved.

telegraphindia.com/india/uttarakh…

Is this the first time Patanjali has been held responsible for misleading consumers?
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Does ‘Coronil’ ring a bell?
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Attempts to establish the credibility of traditional medicine, esp., Ayurveda, dates back to the time prior to India’s independence. Any attempt to question the safety of these Ayurvedic cures is painted as questioning the glory of India’s ancient civilization.
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See how glib talking “experts” try to use the tools of evidence based medicine to build credibility of these concoctions:
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Here is good piece by a public health physician @GorwayGlobal explaining the much touted clinical study conducted by Patanjali: newslaundry.com/2021/02/22/pat…
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While some of this faith is tied to the framing of Ayurveda as an example of India’s allegedly glorious Hindu past, there are several who believe in the supposedly herbal and “chemical free” properties of Ayurvedic concoctions.
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Changing this perception in a country where “scientific temper” is fast disappearing is not easy.

Any reform will require a political class with the courage of conviction to follow the science on Ayurveda & Unani to its logical conclusion.
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Seems unlikely to happen any time soon. Why did the Govt of India lend credibility to these unscientific claims?

science.thewire.in/health/harsh-v…
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As of now, the only viable regulatory option to tackle the Ayurvedic and Unani industry is to simply prohibit the entire industry from making any kind of therapeutic claims. This appears to be the easiest and most politically feasible regulatory model to implement today.
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To that extent, the Ministry of Ayush has taken the right steps in notifying Rule 170, although there is room to sharpen the law on the point. This would in effect reduce Ayurvedic and Unani products to the status of food or supplements.
casemindia.org/wp-content/upl…
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In the long term however, if there is an Ayurvedic product that demonstrates the potential to “cure” or “treat” a disease or ailment, it should go through the same regulatory pathway as any other “new drug” i.e., a rigorous three-phased double-blinded RCT
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to establish its safety and efficacy.

@Preddy85 and I discuss further on the losing battle to regulate Traditional Indian Medicine in our book, ‘The Truth Pill: The Myth of Drug Regulation in India.’

Watch for an upcoming Twitter Spaces conversation on this topic.

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More from @d_s_thakur

Oct 17
Thread 👇

Thread

As @Preddy85 and I were about to begin the session for the launch of the #truthpill this past Saturday evening, like clockwork, we received an email from the @CDSCO_INDIA_INF with a menacing notice threatening

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“to exhaust every available recourse including all possible legal options to take action to dissuade us” from repeating certain comments we made in our interview published in the India Today Interview:
indiatoday.in/india/story/ki…
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Read 39 tweets
Oct 15
Short thread 👇 #truthpill

This entire journey started for @Preddy85 and me with this:

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Where this 👇 was the norm when asked for data/records: Image
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And this is how the data we asked came in: Image
Read 7 tweets
Oct 14
Longish Thread 👇

Want to know what regulatory capture looks like? Read on...

One of the drugs that the Parliamentary Standing Committee in its 59th Report reviewed was the FDC of Flupentixol and Melitracen used to treat depression.
@Preddy85 @truthpill

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The PSC report is available here: casemindia.org/wp-content/upl…

This combination does not exist in any developed markets. The Parliamentary Standing Committee asked for a copy of the approval files from the @CDSCO_INDIA_INF.

This is what it said in its report:
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Responding to this finding of the PSC, the @MoHFW_INDIA constituted a committee to investigate and report on this questionable drug approval under the leadership of Prof T M Mohapatra:
Read 23 tweets
Oct 11
This is the last thread for tonite on the #coughsyrup tragedy in The Gambia.

Earlier today, @chetanabelagere filed a report which has some very interesting findings:

thesouthfirst.com/health/maiden-…
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This 👇 is very interesting. Image
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How did this firm generate six-month real time accelerated stability data when the inspection found no samples of the product in the stability chamber?

One of key requirements for product registration is for the manufacturer to show that its formulation is stable under
Read 7 tweets
Oct 11
Quick follow up thread on the #coughsyrup tragedy in The Gambia.

The official line seems to be that we dont have to worry about adulterated cough syrup because the company is making this product just for its overseas customers.

Lets see if this holds water, shall we?
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Here is a snapshot of the company's catalog showing the line of cough syrups it manufactures: Image
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While they may not selling cough syrup under the names they exported it to the Gambia, they are likely selling cough-syrup in India.

Here are some of their products – we found domestic trademark registrations for Kof-Total which likely means they are selling it in India:
Read 14 tweets
Oct 10
Our book, 'The Truth Pill: The Myth of Drug Regulation in India' is available for purchase on Amazon starting today:

amazon.in/TRUTH-PILL-Myt…

Its a product of many years of research and over 400 RTI responses.

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#truthpill @Preddy85 @SimonSchusterIN
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We wanted to provide our readers direct access to our research because there is only so much we could put into our book. To that end, we are announcing the launch of an accompanying website for #thetruthpill where all our research is curated.

thetruthpill.in
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All primary research for our book is available to journalists, reporters and anyone who is interested in studying this topic further can access it here:

thetruthpill.in/resources/
Read 7 tweets

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