INTRODUCTION: Major depressive disorder (MDD) continues to be one of the highest contributors to disease burden and years lived with disability in the world. Current existing treatments have been associated with intolerable side effects, lo... 2/5
ng onset of action and suboptimal remission rates. Newer agents are being developed that will be reviewed here, such as glutamate and gamma-aminobutyric acid (GABA) and the reinvigorated testing of #psychedelic drugs. This review will summar... 3/5
ize the target mechanisms of the newer ADTs currently in development and available on the market.AREAS COVERED: It briefly covers the existing agents for MDD and treatment-resistant depression (TRD) and the need for new agents with higher e... 4/5
Date: August 2022 Authors: Jennifer Hong, Darian Vernon, Jelena Kunovac, Stephen Stahl 5/5
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Injuries and deaths due to firearms in children and young adults is a public health crisis in the United States. Pediatric clinicians are powerful advocates to reduce harm due to firearms. By forming coalitions wi... 2/5
th legislators on a bipartisan basis, working with government relations teams in the hospitals, and partnering with community allies and stakeholders, pediatric clinicians can work to enact legislation and influen... 3/5
BACKGROUND: This paper explores the feasibility of delivering a music festival-based #drugchecking service in Australia, evaluating service design and stakeholder acceptability.METHODS: Questionnaire and interview data were collected from a... 2/5
dult service users and key stakeholders. A mixed methods approach was used to analyse the data on implementation, impact and acceptability.RESULTS: The trial service tested 170 substances with more than 230 patrons (including individuals wh... 3/5
Attitudes toward #harmreduction and low-threshold healthcare during the COVID-19 pandemic: qualitative interviews with people who use drugs in rural southern Illinois 1/5 doi.org/10.1186/s12954…
BACKGROUND: Chronic health conditions associated with long-term drug use may pose additional risks to people who use drugs (PWUD) when coupled with COVID-19 infection. Despite this, PWUD, especially those living in rural areas, may be less ... 2/5
likely to seek out health services. Previous research has highlighted the increased disease burden of COVID-19 among PWUD. Our manuscript supplements this literature by exploring unique attitudes of PWUD living in rural areas toward the pan... 3/5
Predictors of Retention and Drug Use Among Patients With Opioid Use Disorder Transferred to a Specialty "Second Chance" #Methadone Program 1/5 doi.org/10.1177/117822…
BACKGROUND: Many patients in #methadone treatment have difficulty achieving or maintaining drug abstinence, and many clinics have policies that lead to discharging these patients. We designed a pilot "Second Chance" (SC) program for patients... 2/5
scheduled to be discharged from other local #methadone clinics to be transferred to our clinic.AIM: Determine whether SC patients' retention and opioid use is related to physical or mental health conditions, non-opioid substance use, or tre... 3/5
Evaluating new simplified assays for #harmreduction from methanol poisoning using chromotropic acid kits: An analytical study on Indian and Iranian alcoholic beverages 1/5 doi.org/10.3389/fpubh.…
BACKGROUND: Ingestion of methanol can result in severe irreversible morbidity, and death. Simple and easy methods to detect methanol and other hazardous additives prior to consumption can prevent fatalities. This form of #harmreduction is a... 2/5
nalogous to the widely practiced "pill testing" of recreational drugs in various countries. We aimed to evaluate the performance of two qualitative and quantitative kits to simultaneously identify the presence of methanol and formaldehyde i... 3/5
Implementation of a Leave-behind Naloxone Program in San Francisco: A One-year Experience 1/5 doi.org/10.5811/westje…
INTRODUCTION: In response to the ongoing opioid #overdose crisis, US officials urged the expansion of access to naloxone for opioid overdose reversal. Since then, emergency medical services' (EMS) dispensing of naloxone kits has become an em... 2/5
erging #harmreduction strategy.METHODS: We created a naloxone training and low-barrier distribution program in San Francisco: Project FRIEND (First Responder Increased Education and Naloxone Distribution). The team assembled an advisory com... 3/5