This study in twins found that how effectively an individual awakens in the hours following sleep is associated with sleep quantity/quality the night before, physical activity the day prior, a breakfast rich in carbohydrate, and a lower blood glucose response following breakfast.
- Nights when an individual slept longer than their own typical sleep amount (rather than a standardised sleep amount), were associated with a superior (i.e., higher) degree of next-morning alertness.
- More than just sleep duration, however, sleeping later into the morning than is typical for a given individual (which in part, can give rise to longer sleep duration), predicted higher levels of alertness that following morning.
- Beyond sleep, the second main feature predicting day-to-day changes in morning alertness was the intensity of physical activity the day prior.
In particular, when the extent of an individual’s physical activity was comparatively greater the day prior, individuals experienced higher levels of alertness the next morning.
- The final factor predicting fluctuations in morning alertness was the unique macronutrient composition of food that the individual consumed for their breakfast, not on the day prior, or even the night prior, but the morning of.
Compared to a reference breakfast meal consisting of a standardised (moderate) amount of fat, carbohydrates, and protein (approximately 40/50/10% of energy, respectively)...
...when individuals consumed a higher amount of carbohydrates (77CHO/16FAT/7PRO% of energy breakfast), they experienced higher levels of ensuing alertness.
In contrast, the “High Protein” breakfast predicted a diminished, rather than enhanced, level of alertness following sleep, relative to the reference meal.
- Lastly, the consumption of a pure glucose liquid bolus (oral glucose tolerance test, OGTT) was associated with a marked reduction in alertness levels−the largest drop relative to all the other standardised breakfast meals.
Importantly, this study demonstrates that how effectively an individual awakens in the hours following sleep is not associated with their genetics, but with modifiable factors.
Therefore these factors represent lifestyle-realistic opportunities, or interventional levers, that may aid how an individual (and collectively, a society) awake each day, and sustain that waking alertness.
How people wake up is associated with previous night’s sleep together with physical activity and food intake (open access)

doi.org/10.1038/s41467…

#nutrition #diet

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Nick Krontiris

Nick Krontiris Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @nick_krontiris

Nov 22
This systematic review and meta-analysis suggests that CoQ10 supplementation is likely to improve lipid profiles in adults, with the optimal dose being 400-500mg/day. Image
- CoQ10 supplementation is likely to decrease total cholesterol, LDL-c, and TG and increase HDL-c levels in the adult population.
- Dose–response analysis revealed an inverse J-shaped nonlinear pattern between CoQ10 supplementation and TC, in which the optimal dose was 400 to 500 mg/day.
Read 4 tweets
Nov 22
Using genome-wide association studies (GWAS) of large-scale whole-body MRI data, this one found substantial genetic correlations between body composition measures and a range of cardiometabolic diseases, with the strongest correlation between liver fat and type 2 diabetes. ImageImageImage
Note that where you see MV in the pic above, it's muscle volume, MF is muscle fat infiltration and AFR is Abdmonal Fat ratio.

I think this legend here is more useful, so there you go, for easier comparison/lookup: ImageImage
- "Our findings that a substantial portion of the genetic determinants of these measures are related to the immune system fit with a large body of literature... Image
Read 9 tweets
Nov 22
Here, the consumption of caffeinated coffee was inversely associated with the risk of type 2 diabetes among US nurses with a history of gestational diabetes, with higher intakes being associated with a more favorable glucose metabolic profile among the type 2 diabetes-free women.
A few other notable findings:
- "This current study presents complementary findings on the inverse associations of coffee, particularly caffeinated coffee, with T2D progression for high-risk individuals with a history of GDM...
Read 9 tweets
Nov 21
In this one, healthy postmenopausal women with a family history of type 2 diabetes did not exhibit altered substrate metabolism or oxidation during submaximal exercise nor in the immediate period after exercise.
Therefore, this data suggests that the metabolic defects previously observed in family history of type 2 diabetes "might be limited to contexts where the action of insulin is preponderant...
"...and that exercise metabolism is spared in a healthy population of FDR (first-degree relatives)...
Read 5 tweets
Nov 21
This systematic review found that the majority of the literature suggests that individuals with both mood- and anxiety-related disorders and sleep disorders are likely to have lower heart rate variability during sleep.
- "This suggests that sleep-related ANS dysfunction may be a common but independent factor to both sets of disorders, and may be an underlying reason for the frequent co-occurrence of these conditions...
"...especially given that in healthy individuals, both poor sleep and lower sleep-related HRV are predictors of more severe psychological symptoms"
Read 4 tweets
Nov 21
This one found N-terminal pro-B natriuretic peptide (NT-ProBNP) to independently associated with all-cause mortality and mortality from cardiovascular causes, irrespectively of blood glucose levels, sex, age and body mass index in US adults aged 45–79 years.
- NT-ProBNP levels were associated with all-cause and cardiovascular mortality after a median follow-up of 13 years in people without a previous history of heart failure.
- The association remained consistent after adjustment for known cardiovascular risk factors and socio-behavioral factors.
Read 7 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

:(