Lea Alhilali, MD Profile picture
Nov 26, 2022 13 tweets 7 min read Read on X
1/Tonsillar or peritonsillar abscess? That is the question! When you look at a neck CT, do you know which one to say?
A #tweetorial on #tonsillitis complications
#medtwitter #radtwitter #neurorad #radres #meded #FOAMed #FOAMrad #HNrad #medstudenttwitter #RSNA2022
2/First some anatomy. Palatine tonsils (or faucial to the cool kids) sit in the oropharynx between the two palatine arches: the palatoglossus arch in front and the palatopharyngeus arch in back. These are easily visible on physical exam.
3/These archs are actually just mucosa draped over the palatoglossus and palatopharygeus musculature, like kids drape sheets over themselves to dress up for Halloween.
4/The palatine tonsils sit nestled in between these two arches in a space called the tonsillar fossa. The pillars are like the bed and blankets--and the tonsils are tucked in between
5/Tonsils are made up triangular folds w/crevices in between, called crypts. This anatomy increases tonsillar surface area to expose it to as many of the oropharyngeal antigens as possible. Just below the surface are many lymph node germinal centers to examine the antigens
6/The lymphatic channels from these germinal centers are valveless (in adults—I don’t do kids 😉). This allows for immediate transport of antigens. This makes sense, as you want to be aware of any bad antigen entering your oropharynx as soon as possible
7/Tonsillitis occurs when there is an infection of the tonsils, usually strep pneumo. Inflammatory debris is made in the crypts and excreted out, creating the white patches seen on physical exam
8/On CT, this inflammatory change causes enlargement of the tonsils and hyper-enhancement of the crypts. This results in the classic tiger-stripe appearance of tonsillitis.
9/An abscess occurs when one of these crypts gets obstructed and its inflammatory exudate turns into pus under pressure.
10/But the pus doesn’t stay in the tonsil. It’s under pressure, like a volcano. If it’s plugged, the lava will find a way out b/c of the pressure. Lava will flow out any cracks/pores in the rock. In the tonsil, pores are the valveless lymphatics that allow the pus to flow out
11/Trying to keep the pus in the tonsil is like trying to keep water in a bathtub when the drain is open. It will always pour out. Similarly, in adults, the pus never stays in the tonsil—it pours out the valveless lymphatics into the tonsillar fossa/peritonsillar space.
12/Once the pus is in the tonsillar fossa, it becomes a peritonsillar abscess. It does not have to go through the superior constrictor musculature to be considered a peritonsillar abscess
13/So, in adults, the answer to the question “Tonsillar or peritonsillar abscess?” is the same answer my kid knows to give when asked, “Which parent do you love the most?” The answer: both!

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More from @teachplaygrub

Aug 19
1/Do questions about brainstem anatomy cause you to suddenly get a case of locked in syndrome?!

Do you try to localize the lesion or just wait for the MR?

Wait no more!

Here’s a thread about the brainstem Rule of Four to help you localize brainstem lesions! Image
2/The hallmark of a brainstem lesion/syndrome is:

(1) Ipsilateral cranial nerve deficit

(2) Contralateral body deficit (be it weakness, sensory loss, or ataxia) Image
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Similarly, the cranial nerve deficit can be the opposite of the body deficit

This split between head and body is key for recognizing brainstem syndromes Image
Read 12 tweets
Aug 16
1/Is your understanding of medial temporal anatomy, well, temporary?

If only there was a way to make hippocampal anatomy memorable!

Here is a thread of the basics of hippocampal anatomy that will hopefully stay in your hippocampus! Image
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Early anatomists thought it looked like an upside down seahorse—w/its curved tail resembling the tail of a seahorse.

Hippocampus literally means seahorse. Image
3/In cross section, it has a spiral appearance, leading to its other name, Cornu Ammonis, translated Ammon’s Horn.

Ammon was an Egyptian god w/spiraling rams horns.

The hippocampal subfields are abbreviated CA-1, CA-2, etc, w/CA standing for “Cornu Ammonis” Image
Read 17 tweets
Aug 9
1/Tired of stressing if a brain tumor is progressing?

Wish you had some insurance about calling tumor recurrence?

Here’s the cheat sheet you NEED for the best signs of tumor progression! Image
2/Just when treatment thinks it’s got tumor trapped at cliff, tumor is able to get away

Think how you would get away if you were chased to a cliff’s edge.

These are same signs of tumor progression! Image
3/Here's how both you and the tumor can escape:

1. Jump off into the water:
Tumor heads to the water—the ventricular surface

Subependmyal enhancement is very specific for tumor progression (93% sensitivity), but it isn’t commonly seen (38% sensitive). Image
Read 8 tweets
Aug 7
1/Tired of always speculating about MR spectroscopy?

If you've ever looked at an MR spectroscopy & thought: "I have no idea what I’m looking at!"--then this cheat sheet is for you!

Here's a thread on the 4 basic rules you need to understand the spectrum of basic spectroscopy! Image
2/First you need to know the peaks.

There are 3 main peaks: Choline, Creatine, NAA

Remember the order bc a spectrum looks like mountain peaks & it is cold in the mountains.

And CHOld CREATures NAp or hibernate in the mountains Image
3/First peak is Choline

It's a marker of membrane turnover

You can remember this because membranes coat or “CHOat” the cell Image
Read 11 tweets
Aug 2
1/Wish that your knowledge of autoimmune encephalitis was automatic?

Do you feel in limbo when it comes to the causes of limbic encephalitis?

Do you know the patterns of autoimmune encephalitis?

Here’s a thread with some hints to help you figure it all out! Image
2/Two pearls:
(1) Most common pattern is limbic encephalitis
(2) Small cell can cause any autoimmune pattern.

You can also remember the causes by the demographic:
🔸Young man: testicular
🔸Older: Small cell
🔸Woman with psychiatric symptoms: breast Image
3/Limbic encephalitis is the most common pattern

But it has many, many different causes

Remember--limbic involvement is shaped like a question mark!

So for limbic encephalitis, the cause remains a question bc the differential is so broad

Must question & clinically correlate! Image
Read 7 tweets
Jul 23
1/To call it or not to call it? That is the question!

Do you feel a bit wacky & wobbly when it comes to calling normal pressure hydrocephalus on imaging?

You don’t want to overcall it, but you don’t want to miss it either!

Let me help you out w/a thread about imaging in NPH! Image
2/First, you must understand the pathophysiology of “idiopathic” or iNPH.

It was first described in 1965—but, of the original six in the 1965 cohort, 4 were found to have underlying causes for hydrocephalus.

This begs the question—when do you stop looking & call it idiopathic? Image
3/Thus, some don’t believe true idiopathic NPH exists.

After all, it’s a syndrome defined essentially only by response to a treatment w/o ever a placebo-controlled trial.

However, most believe iNPH does exist--but underlying etiology is controversial. Several theories exist Image
Read 19 tweets

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