Lea Alhilali, MD Profile picture
Dec 7, 2022 18 tweets 9 min read Read on X
1/Have disagreements between radiologists on the degree of cervical canal stenosis become a pain in the neck?!
Here’s a #tweetorial on cervical stenosis grading that’s easy, reproducible & evidence based
#medtwitter #spine #neurosurgery #radres #neurorad #meded #FOAMed #FOAMrad Image
2/In the lumbar spine, it is all about the degree of canal narrowing & room for nerve roots. In the cervical spine, we have another factor to think about—the cord. Cord integrity is key. No matter the degree of stenosis, if the cord isn’t happy, the patient won’t be either Image
3/Cord flattening, even w/o canal stenosis, can cause myelopathy. No one is quite sure why. Some say it’s b/c mass effect on static imaging may be much worse in dynamic positions, some say it’s repetitive microtrauma, & some say micro-ischemia from compression of perforators Image
4/Let’s start w/canal stenosis. Measurements have been proposed (<10mm), but this is cumbersome & introduces reader variability. Think functionally. Cord swims in CSF, like a fish in water. Like a fish, it needs room to swim. How much room is in the fish bowl determines stenosis Image
5/Mild stenosis is when your fish bowl decorations take up 1 side of the bowl. Not great, but fish can still swim. Moderate means your decorations take up both sides—swimming is really affected. Severe means you went all out w/decorations & there isn’t any more room for the fish Image
6/The sides of the fish bowl are the ventral & dorsal CSF. So mild canal stenosis is when either the ventral or dorsal CSF is effaced, but the other side of the fish bowl is still empty. Not ideal, but the fish can still swim Image
7/For moderate canal stenosis, both sides of the fish bowl have been filled. So both the ventral and dorsal CSF have been effaced. Now the room to swim has been notably limited Image
8/Finally, in severe canal stenosis, the bowl is completely filled and no CSF is seen. There is no room for the fish in this scenario. Similarly, there is no room for the cord and it is compressed. Not only is there no swimming, the fish has been crushed. Image
9/This classification is to all other classifications like a goldfish is to all other pets—super easy & simple. It’s also evidence based. It's the Muhle classification. It has excellent reproducibility. It hasn’t been correlated w/pain, but it's been correlated w/SSEP & outcomes Image
10/But canal stenosis isn’t enough. Cord flattening can cause myelopathy regardless of degree canal stenosis. It’s like being punched in the face—no matter how far away the hit comes from, it still hurts. Cord flattening is like being punched—it hurts even in mild stenosis Image
11/Think of the canal like a parking space. Even if no one encroaches on your space, if someone opens their door & dings your car, your car is still damaged and you are still mad. Your parking space may still be wide open, but you still have a nick in your door. Image
12/Cord flattening has 3 degrees. Either it’s not there, there, or so bad it causes cord damage. Think of it like a fight. Cord deformity w/o signal is like someone pushing you to start a fight---you can still walk away. Cord deformity w/signal is a punch to the face—it’s on! Image
13/Here are examples:

Cord deformity w/o signal (Grade 2, someone pushing and trying to start something)

Deformity w/cord signal (Grade 3, fight has already started & the cord already has a black eye!) Image
14/Remember, this is independent of the degree of canal stenosis. You can have cord deformity and signal even in lesser degrees of canal stenosis. Remember--cord flattening can cause cord damage regardless of the degree of canal stenosis. Image
15/This is the Kang system, and it was created to bring the idea of cord flattening into the rating of cervical spine stenosis, since flattening/deformity contribute to myelopathy regardless of stenosis. Image
16/Why don’t we just use the Kang & forget Muhle? Well, the problem w/Kang is that if there’s no cord signal, many degrees of canal stenosis are equal. Here, both mild stenosis w/flattening & severe stenosis w/flattening are equal in Kang, but clearly one is much more at risk Image
17/So we use both. For every level, we rate the degree of canal stenosis according to Muhle & the degree of cord flattening according to Kang. Remember—there is no perfect classification system. Sometimes you need combine. Image
18/So remember both canal and cord matter in the cervical region! Degree of stenosis is important, but even w/o it, cord flattening can have you swimming w/the fishes. So hopefully, you will take to these rating systems like a fish to water! Image

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More from @teachplaygrub

Aug 19
1/Do questions about brainstem anatomy cause you to suddenly get a case of locked in syndrome?!

Do you try to localize the lesion or just wait for the MR?

Wait no more!

Here’s a thread about the brainstem Rule of Four to help you localize brainstem lesions! Image
2/The hallmark of a brainstem lesion/syndrome is:

(1) Ipsilateral cranial nerve deficit

(2) Contralateral body deficit (be it weakness, sensory loss, or ataxia) Image
3/You can remember this because often your head has certain feelings that opposite the feelings in your heart/body.

Similarly, the cranial nerve deficit can be the opposite of the body deficit

This split between head and body is key for recognizing brainstem syndromes Image
Read 12 tweets
Aug 16
1/Is your understanding of medial temporal anatomy, well, temporary?

If only there was a way to make hippocampal anatomy memorable!

Here is a thread of the basics of hippocampal anatomy that will hopefully stay in your hippocampus! Image
2/Its name “hippocampus” comes from its shape on gross anatomy.

Early anatomists thought it looked like an upside down seahorse—w/its curved tail resembling the tail of a seahorse.

Hippocampus literally means seahorse. Image
3/In cross section, it has a spiral appearance, leading to its other name, Cornu Ammonis, translated Ammon’s Horn.

Ammon was an Egyptian god w/spiraling rams horns.

The hippocampal subfields are abbreviated CA-1, CA-2, etc, w/CA standing for “Cornu Ammonis” Image
Read 17 tweets
Aug 9
1/Tired of stressing if a brain tumor is progressing?

Wish you had some insurance about calling tumor recurrence?

Here’s the cheat sheet you NEED for the best signs of tumor progression! Image
2/Just when treatment thinks it’s got tumor trapped at cliff, tumor is able to get away

Think how you would get away if you were chased to a cliff’s edge.

These are same signs of tumor progression! Image
3/Here's how both you and the tumor can escape:

1. Jump off into the water:
Tumor heads to the water—the ventricular surface

Subependmyal enhancement is very specific for tumor progression (93% sensitivity), but it isn’t commonly seen (38% sensitive). Image
Read 8 tweets
Aug 7
1/Tired of always speculating about MR spectroscopy?

If you've ever looked at an MR spectroscopy & thought: "I have no idea what I’m looking at!"--then this cheat sheet is for you!

Here's a thread on the 4 basic rules you need to understand the spectrum of basic spectroscopy! Image
2/First you need to know the peaks.

There are 3 main peaks: Choline, Creatine, NAA

Remember the order bc a spectrum looks like mountain peaks & it is cold in the mountains.

And CHOld CREATures NAp or hibernate in the mountains Image
3/First peak is Choline

It's a marker of membrane turnover

You can remember this because membranes coat or “CHOat” the cell Image
Read 11 tweets
Aug 2
1/Wish that your knowledge of autoimmune encephalitis was automatic?

Do you feel in limbo when it comes to the causes of limbic encephalitis?

Do you know the patterns of autoimmune encephalitis?

Here’s a thread with some hints to help you figure it all out! Image
2/Two pearls:
(1) Most common pattern is limbic encephalitis
(2) Small cell can cause any autoimmune pattern.

You can also remember the causes by the demographic:
🔸Young man: testicular
🔸Older: Small cell
🔸Woman with psychiatric symptoms: breast Image
3/Limbic encephalitis is the most common pattern

But it has many, many different causes

Remember--limbic involvement is shaped like a question mark!

So for limbic encephalitis, the cause remains a question bc the differential is so broad

Must question & clinically correlate! Image
Read 7 tweets
Jul 23
1/To call it or not to call it? That is the question!

Do you feel a bit wacky & wobbly when it comes to calling normal pressure hydrocephalus on imaging?

You don’t want to overcall it, but you don’t want to miss it either!

Let me help you out w/a thread about imaging in NPH! Image
2/First, you must understand the pathophysiology of “idiopathic” or iNPH.

It was first described in 1965—but, of the original six in the 1965 cohort, 4 were found to have underlying causes for hydrocephalus.

This begs the question—when do you stop looking & call it idiopathic? Image
3/Thus, some don’t believe true idiopathic NPH exists.

After all, it’s a syndrome defined essentially only by response to a treatment w/o ever a placebo-controlled trial.

However, most believe iNPH does exist--but underlying etiology is controversial. Several theories exist Image
Read 19 tweets

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