Lea Alhilali, MD Profile picture
Dec 7, 2022 18 tweets 9 min read Read on X
1/Have disagreements between radiologists on the degree of cervical canal stenosis become a pain in the neck?!
Here’s a #tweetorial on cervical stenosis grading that’s easy, reproducible & evidence based
#medtwitter #spine #neurosurgery #radres #neurorad #meded #FOAMed #FOAMrad Image
2/In the lumbar spine, it is all about the degree of canal narrowing & room for nerve roots. In the cervical spine, we have another factor to think about—the cord. Cord integrity is key. No matter the degree of stenosis, if the cord isn’t happy, the patient won’t be either Image
3/Cord flattening, even w/o canal stenosis, can cause myelopathy. No one is quite sure why. Some say it’s b/c mass effect on static imaging may be much worse in dynamic positions, some say it’s repetitive microtrauma, & some say micro-ischemia from compression of perforators Image
4/Let’s start w/canal stenosis. Measurements have been proposed (<10mm), but this is cumbersome & introduces reader variability. Think functionally. Cord swims in CSF, like a fish in water. Like a fish, it needs room to swim. How much room is in the fish bowl determines stenosis Image
5/Mild stenosis is when your fish bowl decorations take up 1 side of the bowl. Not great, but fish can still swim. Moderate means your decorations take up both sides—swimming is really affected. Severe means you went all out w/decorations & there isn’t any more room for the fish Image
6/The sides of the fish bowl are the ventral & dorsal CSF. So mild canal stenosis is when either the ventral or dorsal CSF is effaced, but the other side of the fish bowl is still empty. Not ideal, but the fish can still swim Image
7/For moderate canal stenosis, both sides of the fish bowl have been filled. So both the ventral and dorsal CSF have been effaced. Now the room to swim has been notably limited Image
8/Finally, in severe canal stenosis, the bowl is completely filled and no CSF is seen. There is no room for the fish in this scenario. Similarly, there is no room for the cord and it is compressed. Not only is there no swimming, the fish has been crushed. Image
9/This classification is to all other classifications like a goldfish is to all other pets—super easy & simple. It’s also evidence based. It's the Muhle classification. It has excellent reproducibility. It hasn’t been correlated w/pain, but it's been correlated w/SSEP & outcomes Image
10/But canal stenosis isn’t enough. Cord flattening can cause myelopathy regardless of degree canal stenosis. It’s like being punched in the face—no matter how far away the hit comes from, it still hurts. Cord flattening is like being punched—it hurts even in mild stenosis Image
11/Think of the canal like a parking space. Even if no one encroaches on your space, if someone opens their door & dings your car, your car is still damaged and you are still mad. Your parking space may still be wide open, but you still have a nick in your door. Image
12/Cord flattening has 3 degrees. Either it’s not there, there, or so bad it causes cord damage. Think of it like a fight. Cord deformity w/o signal is like someone pushing you to start a fight---you can still walk away. Cord deformity w/signal is a punch to the face—it’s on! Image
13/Here are examples:

Cord deformity w/o signal (Grade 2, someone pushing and trying to start something)

Deformity w/cord signal (Grade 3, fight has already started & the cord already has a black eye!) Image
14/Remember, this is independent of the degree of canal stenosis. You can have cord deformity and signal even in lesser degrees of canal stenosis. Remember--cord flattening can cause cord damage regardless of the degree of canal stenosis. Image
15/This is the Kang system, and it was created to bring the idea of cord flattening into the rating of cervical spine stenosis, since flattening/deformity contribute to myelopathy regardless of stenosis. Image
16/Why don’t we just use the Kang & forget Muhle? Well, the problem w/Kang is that if there’s no cord signal, many degrees of canal stenosis are equal. Here, both mild stenosis w/flattening & severe stenosis w/flattening are equal in Kang, but clearly one is much more at risk Image
17/So we use both. For every level, we rate the degree of canal stenosis according to Muhle & the degree of cord flattening according to Kang. Remember—there is no perfect classification system. Sometimes you need combine. Image
18/So remember both canal and cord matter in the cervical region! Degree of stenosis is important, but even w/o it, cord flattening can have you swimming w/the fishes. So hopefully, you will take to these rating systems like a fish to water! Image

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Apr 25
1/Have some confusion about tumor perfusion?

Do you go into a coma looking at scans for glioma?

Never fear!

Read on for this month's @theAJNR SCANtastic for what you need to know on the latest in brain tumor imaging!

ajnr.org/content/45/4/4…
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@TheAJNR 2/Since the prehistoric days of medicine (1979!), we knew that some brain tumor patients treated w/radiation (XRT) initially declined, but then get better.

Today, we see this on imaging, where it looks worse early, but then gets better.

Now we call this pseudoprogression. Image
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XRT induces a lot of inflammatory changes—from initiating the complement cascade to opening the blood brain barrier (BBB)

It’s these inflammatory changes that make the imaging look worse. Image
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Apr 19
1/Having trouble remembering how to differentiate dementias on imaging?

Is looking at dementia PET scans one of your PET peeves?

Here’s a thread to show you how to remember the imaging findings in dementia & never forget! Image
2/The most common functional imaging used in dementia is FDG PET. And the most common dementia is Alzheimer’s disease (AD).

On PET, AD demonstrates a typical Nike swoosh pattern—with decreased metabolism in the parietal & temporal regions Image
3/The swoosh rapidly tapers anteriorly—& so does hypometabolism in AD in the temporal lobe. It usually spares the anterior temporal poles.

So in AD look for a rapidly tapering Nike swoosh, w/hypometabolism in the parietal/temporal regions—sparing the anterior temporal pole Image
Read 16 tweets
Apr 18
1/”That’s a ninja turtle looking at me!” I exclaimed.

My fellow rolled his eyes, “Why do I feel I’m going to see this on X or twitter soon…”

He was right!

A thread about one of my favorite imaging findings & pathology behind it ! Image
2/Now the ninja turtle isn’t an actual sign—yet!

But I am hoping to make it go viral as one.

To understand what this ninja turtle is, you first have to know the anatomy in this region.

I have always thought the medulla looks like a 3 leaf clover in this region. Image
3/ The most medial bump of the clover is the medullary pyramid (motor fibers).

Next to it is the inferior olivary nucleus (ION), & finally, the last largest leaf is the inferior cerebellar peduncle.

Now you can see that the ninja turtle eyes correspond to the ION. Image
Read 11 tweets
Apr 17
1/CSF leaks are controversial!

Some say they're overdiagnosed, others underdiagnosed

How can YOU make sure you aren’t under or overdiagnosing?

Are you BERN-ing to know when to suspect CSF leak?

Here’s a 🧵about the CSF leak Bern score so you don’t get BERN-ed by CSF leaks Image
2/In CSF leaks, everyone knows about brain sagging.

But this can happen w/other diseases, ie Chiari 1.

Other findings can be seen on brain MRI in CSF leaks.

But what are these findings & are some findings more suggestive than others?

Do⬆️findings = ⬆️suspicion? Image
3/The Bern group looked at 9 quantitative & 7 qualitative signs seen on brain MRI in CSF leaks to see which are most important.

Depending on type & # of findings, they developed a score to indicate what level of suspicion you should have for a leak. Image
Read 15 tweets
Apr 15
1/Is remembering cerebellar anatomy making you dizzy?

Need help telling your flocculus from your nodule?

How much cerebellar anatomy do YOU know?

Here’s some help w/an anatomy thread on the 9 lobules of the vermis! Image
2/Coming from anterior, the first lobule is the lingula

It sticks out from the front of the vermis & is connected to the superior cerebellar peduncle (SCP)

I remember this bc of its very appropriate name—lingula—it looks like a tongue sticking out of the vermis to lick the SCP Image
3/Moving clockwise, next is the central lobule

I remember this bc it's positioned exactly how a central lobule should be positioned, in the driver’s seat!

It's where the front driver position would be if the vermis was a car—up front, looking out a windshield over the lingula Image
Read 12 tweets
Apr 12
1/Time is brain! But what time is it?

If you don’t know the time of stroke onset, are you able to deduce it from imaging?

Here’s a thread to help you date a stroke on MRI! Image
2/In ~25% of acute stroke patients, the time of last known well is well, not known.

Then it’s important to use the stroke’s MR imaging features to help date its timing.

Is it hyperacute? Acute? Subacute? Or are the “stroke” symptoms from a seizure from their chronic infarct? Image
3/Strokes evolve, or grow old, the same way people evolve or grow old.

Appearance of stroke on imaging mirrors the life stages of a person—you just have to change days for a stroke into years for a person.

So 15 day old stroke has features of a 15 year old person, etc. Image
Read 22 tweets

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