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Nick Krontiris

@nick_krontiris

Dec 30

This one suggests that intermittent fasting with higher-quality, nutrient-dense meals that are evenly spaced throughout the day and provide 20-40g of protein may be superior to a heart-healthy caloric restriction diet in terms of body composition outcomes.

- The IF approach used is a modified IF regimen, which allows consumption of 20% to 25% of energy needs on scheduled fasting days (36-60hrs/wk).

For the rest 5 or 6 days of the week, a meal plan with a macronutrient distribution targeting 35% protein, 35% carbohydrate, and 30% fat was delivered.

Read 12 tweets

Nick Krontiris

@nick_krontiris

Dec 30

Although the findings of this one suggest health benefits of substituting sedentary behavior with higher levels of physical activity during a weight-loss maintenance effort, it also found that the effect of these activity substitutions on weight change is likely marginal at best.

- This prospective study included 1152 adults from the NoHoW trial who had achieved a successful weight loss of ≥5% during the 12 months prior to baseline and had BMI ≥25 kg/m2 before losing weight.

- Substitution of baseline sedentary behavior with moderate-to-vigorous physical activity was associated with a decrease in body fat percentage during the first 6 months of the trial but was not associated with 6-, 12-, or 18-month change in body weight.

Read 7 tweets

Nick Krontiris

@nick_krontiris

Dec 29

This one found adherence to multiple healthy lifestyle factors to be associated with improved circulating metabolites from different pathways, with fatty acids mediating the association between all 5 lifestyle factors and the risk of CVD in individuals with diabetes.

- This study aimed to provide a comprehensive assessment of the associations of multiple lifestyle factors (waist circumference, smoking status, alcohol intake, physical activity, and diet) with nuclear magnetic resonance (NMR) metabolomics among individuals with diabetes.

- Adherence to healthy lifestyle factors, including non central obesity, non-current smoking, moderate alcohol intake, physically active, and healthy diet, was associated with 44 plasma metabolites across multiple metabolic pathways.

Read 18 tweets

Nick Krontiris

@nick_krontiris

Dec 29

This systematic review and meta-analysis comes to the conclusion that n-3 PUFA supplementation is likely to lead to very small increases in muscle strength, but it is not likely to confer an impact in muscle mass and function in healthy adults (young and older).

- "Our results are in contrast with the meta-analysis published by Huang et al, who found minor increases in muscle mass and function in the elderly after n-3 PUFA supplementation...

Ref:
doi.org/10.3390/nu1212…

"...The fact that they included measurements of muscle mass based on DXA, bioelectrical impedance analysis, and computed tomography, while we only considered gold-standard measurements... may help to explain the discrepancy between our findings...

Read 7 tweets

Nick Krontiris

@nick_krontiris

Dec 29

In this one, increased accumulation of visceral adipose tissue was found to be associated with lower paraspinal muscle tissue density, an indicator of fatty infiltration and a known risk factor for falls in US adults with a mean age of ~45 years.

- After adjustment for covariates, both men and women with the greatest accumulation of VAT over six years had lower paraspinal density at the follow-up.

- Even though the distributions of VAT and muscle density were different between men and women, the same inverse association was observed in men and in both pre- and post- menopausal women.

Read 4 tweets

Nick Krontiris

@nick_krontiris

Dec 29

Here, 6 months of active commuting or vigorous intensity leisure-time exercise was associated with long-term maintenance of improvements in VO2peak and body composition, whereas moderate intensity leisure-time exercise was not.

Stay tuned, because this gets interesting near the end!

- Individuals with overweight/obesity, who completed a 6-month exercise intervention (active commuting by bike, moderate, or vigorous intensity leisure-time exercise), were after one year invited to participate in a follow-up visit.

Read 14 tweets

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