VIRAL PERSISTENCE
IT IS THE MAIN CAUSE OF MYOCARDITIS IN #LONGCOVID
In 85.7%(12/14) of Endomyocardial Biopsies
persistence of up to 18 months of SARS CoV2 was detected
It was identified in Cardiomyocytes,Endothelium,Macrophages
Also Anticardiac Antibodies
onlinelibrary.wiley.com/doi/10.1002/cl…
None of the 14 cases had severe respiratory failure or evidence of cardiac injury during Acute COVID
In all of them Myocarditis only manifested itself after the acute phase of COVID
In #LongCOVID #PACS
This was diagnosed 2 to 18 months later
and confirmed by Endomyocardial Biopsy
In 2of the cases
47year-o. women
Myocarditis symptoms appeared only after vaccination
this means
who were carriers of a latent infection
Authors point out:
This suggests a triggering (resolving) role of the vaccine
when administered after an infection
that can remain asymptomatic
SARS CoV2 infection has been shown to
even in its mild/asymptomatic forms
It is a powerful latent Virus Reactivator
For their part
Vaccines
by imitating an infection xSARS Co2
it can also Reactivate and Potentiate/Enhancement pre-existing latent infections
These cases are further evidence of the existence
of carriers of
ASYMPTOMATIC OR LATENT PERSISTENT INFECTION

In another study
SARS CoV2 was detected in 25% of children who had not manifested symptoms related to COVID and who had a negative nasopharyn. PCR

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More from @Aguirre1Gustavo

Dec 27
PERSISTENCIA VIRAL
ES PRINCIPAL CAUSA DE MIOCARDITIS EN #LONGCOVID
En el 85,7% (12/14)
de las Biopsias Endomiocárdicas se detectó persistencia de hasta 18 meses del SARS CoV2
Se identificó en Cardiomiocitos, Endotelio, Macrófagos
Además Antic.Anticardiacos
onlinelibrary.wiley.com/doi/10.1002/cl…
Ninguno de los 14casos tubo insuficiencia respiratoria grave ni evidencia de lesión cardíaca durante el COVID Agudo
En todos, la Miocarditis recién se manifestó después de la fase aguda de COVID
Esta fue diagnosticada 2 a 18meses después
y confirmada por la Biopsia Endomiocárdica
En 2de los casos
mujeres de 47años
los síntomas de Miocarditis aparecieron solo después de la vacunación
es decir
eran portadoras de una infección latente
Autores señalan:
Esto sugiere un papel desencadenante de la vacuna
cuando se administra después de una infección asintomática
Read 4 tweets
Dec 16
PAXLOVID versus TRUVADA
FOR CHRONIC COVID #LONGCOVID #PACS
For costs and side effects
and as months of treatment are required
Win Truvada
containing
Emtricitabine FTC+
Tenofovir Disoproxil FumarateTDF
One could start with Paxlovid and continue with Truvada
PROTOCOLS FOR CHRONIC COVID #LONGCOVID

I. INTENSIVE PHASE AGAINST VIRAL LOAD
It includes:
1.FTC/TDF (Truvada). The alternative is to start Paxlovid for 10-25 days and then continue with FTC/TDF
2. IVM or Liposomal Artemisinin or Artesunate
3. ECGC or Nitazoxanide or Ozone 10pass
The objective of the INTENSIVE PHASE in CHRONIC COVID #LONGCOVID
is to minimize the Viral Load
Lasts 1-2months
Then follows the Maintenance Phase
whose objective is to avoid the Relapse/Reactivation of the infection
The number of drugs is reduced
Lasts 3 to 8months
depending
case
Read 5 tweets
Nov 21
ASYMPTOMATIC OR LATENT PERSISTENT INFECTION IN CHILDREN.

SARS COV-2 WAS DETECTED IN BIOPSIES OF TONSILS OR ADENOIDS
IN 25% OF ASYMPTOMATIC CHILDREN
None had experienced signs or symptoms

Authors point out:
lymphoid tissue may be a Reservoir of SARS-CoV-2
doi.org/10.1016/j.bjor…
It had already been identified that the Biofilm or Dental Plaque harbors SARS CoV-2
To this is added the Tonsils and Adenoids in children
Therefore, it is confirmed that the oral cavity is a potential reservoir for the virus
There are Asymptomatic Carriers
In #LongCOVID
For Viral Persistence,
for having Drug-Resistance
we indicate 3 or more medications or supplements with effects against Viral Load
In addition
any infectious focus at the oral level must be eliminated by the Dentist
and mouthwash is indicated
Read 5 tweets
Nov 15
AUTOPSY IN A CHILDREN WITH MULTISYSTEM INFLAMMATORY SYNDROME (MIS-C)
SHOWS VIRAL PERSISTENCE IN MULTIPLE ORGANS
Authors point out
persistence of SARS-COV-2 is a feature in all autopsies of MIS-C patients reported to date, suggesting a role in pathogenesis
doi.org/10.1016/j.prp.…
A symptom of Hypoperfusion,Hypercoagulability and Microclots (HHM) are the
MUSCLE SPASM,
TWICHING or
FASCICULATIONS
That in children, adolescents and adults of low weight,
can be diagnosed as
INVOLUNTARY MOVEMENTS of neurological origin
but the problem is in the blood circulation
It is confirmed that the cause of #LongCOVID is Viral Persistence
Apply at home, free of charge, the HHM Test questionnaire
With the result the Treatment will be established.
There is a correlation between the level of the Viral Load and that of Microclots researchgate.net/publication/36…
Read 4 tweets
Nov 7
IN HOSPITAL IN LONDON, UK, THEY DEMONSTRATE THAT THE LONG COVID (OR CHRONIC COVID) IS DUE TO VIRAL PERSISTENCE
And by means of sequencing of the complete genome (WGS) they identify mutations that cause Drug-Resistance
Report 4 cases with #LongCOVID treated
doi.org/10.1093/cid/ci… Image
Case2 corresponds to a patient with #LongCOVID who spent 411days with viral persistence confirmed by PCR Through WGS:Whole Genome Sequencing it is shown that the virus mutates within the patient's body and Drug-Resistance develops
TheWGS guided Antiviral and Monoclonal Ab therapy
We have been very clear since April 2020 that Viral Persistence is the main cause of #LongCOVID
In our 1st Report we mentioned the tendency to Viral Persistence in part of the cases
The Rebound that is observed Paxlovid
we observed it in April2020 with IVM researchgate.net/publication/34…
Read 9 tweets
Nov 7
EN HOSPITAL EN LONDRES, UK, DEMUESTRAN QUE EL LONG COVID O COVID PERSISTENTE ES DEBIDA A PERSISTENCIA VIRAL
Y mediante secuenciación del genoma completo (WGS) identifican mutaciones que ocasionan Drogo-Resistencia.
Reportan 4 casos con #LongCOVID tratados
doi.org/10.1093/cid/ci… Image
El Caso 2 corresponde a un paciente con #LongCOVID que estuvo 411 días con Persistencia viral confirmada mediante PCR. Mediante la WGS se demuestró que el virus muta dentro del organismo y se desarrolla Drogo-Resistencia.
La WGS guio la terapia con Ac Monoclonales y Antivirales
Tenemos claro desde Abril2020 que la Persistencia Viral es la principal causa de LongCOVID
En nuestro 1er Reporte mencionamos la tendencia a la Persistencia Viral en parte de los casos
El Rebote que se observa con Paxlovid
lo observamos en Abril2020 conIVM
researchgate.net/publication/34…
Read 9 tweets

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