It's wild and bad that Biontech tried to get public mentions of #CTAP, a @WHO housed initiative to pool intellectual property, scrapped as "vaccine misinformation".

This is not the pharma's first bizarre anti-generics campaign. A quick bit of history.🧵1/
My 'favourite' absurd anti-generics lobbying story is the time PhRMA commissioned a novel about why generic medicines were bad.

It never was published because even the paid ghostwriters wouldn't take it as far as PhRMA wanted.

I wrote abt it here ⬇️2/

The authors re-wrote a less terrible version, and PhRMA freaked out that it might be published / tried to get a court order to recall all copies.

The attention to detail is extreme, including getting CNN to get Larry King to recall a cover blurb. 3/
huffpost.com/entry/phrma-co…
During the early years of the HIV epidemic, it wasn't just censoring tweets about WHO initiatives. WHO officials themselves had very real reasons to believe that their lives were at risk. 4/

theguardian.com/world/2001/aug…
If you ever apply for a job with WHO, there's an odd checkbox where you confirm that not only do you not have tobacco COIs, but you don't even smoke yourself.

That may seem a little extra, until you read abt the scale of the campaign against FCTC. 5/
reuters.com/investigates/s…
Lobbying is (unfortunately) good value for money. Pharma spent a half billion in the last 2 years lobbying Congress. Key aims were blocking drug pricing reform and the #TRIPSWaiver.

But it's small change when you understand the money to be made here. 6/
opensecrets.org/industries/lob… Image
Close pharma ally Orrin Hatch kept busy using his power in Congress to threaten folks trying to expand generic access to medicines.

This included, among other things, threats to the Global Fund abt generics use / IP issues: 7/
ip-watch.org/2013/02/12/let…

statnews.com/2018/01/02/sen…
Another Hatch-related episode: the Senate Finance committee threatened Colombia over a potential compulsory license on a cancer medicine.

Among other things, funding for the *checks notes* peace process was threatened. 8/

theintercept.com/2016/05/14/lea…
South Africa has been working to reform their patent laws (fixthepatentlaws.org). PhRMA underwrote a campaign to astroturf opposition and delay (or block) much-needed reforms. Here were some of their aims ⬇️ 9/

mg.co.za/article/2014-0…

keionline.org/22398 Image
What I think folks have a hard time understanding is the attention to detail. The above were all major generics initiatives, so you understand the opposition.

But there's a remarkable (horrifying) attention to detail in that even small fish in this space (hi!) feel pressure.
I was fresh out of school, w/a little baby abstract in a minor conference when I was contacted by a press officer & informed a pharma company was angry at (publicly available) drug prices that were part of my study, & I was at risk of a libel lawsuit if I didn't change them. 10/
Pharma (this time IFPMA, pharma's int'l counterpart) paid more money to a consultancy to write a piece about why my research is bad than I have ever been paid to *actually do* my research.

This is a matter of public record.
ohe.org/publications/2… 11/ Image

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More from @mellabarb

Jan 12
Jan 2023 #Paxlovid costing update:🧵

9 months later, no real news.
❌generic supply is still not widely available
❌Pfizer is refusing to expand licensing
🥴no trial data on how it works in key populations

Updated cost-based estimated generic price: $15
scholar.harvard.edu/melissabarber/…
Here's the top-line summary, using current prices of API traded in global markets.

#Paxlovid is $530 in the US. It has been reported that in China right now, desperate people have been paying as much as $7,000 to get it for their loved ones. 2/
reuters.com/business/healt… Image
Cost-based estimated generic prices use the price of active pharmaceutical ingredient (API) traded in global markets, and a cost estimation algorithm we developed in earlier research (see gh.bmj.com/content/3/1/e0…)

Costs come down exponentially when there is competition, but.. 3/ Image
Read 14 tweets
Oct 14, 2022
I saw videos I posted retweeted out of context, so I want to be clear abt a few things.

What has happened this week is pharma's failure to show up & be transparent abt contracts and pricing has fanned the flames of of distrust about vax effectiveness.

That's a problem.🧵1/5
I encourage folks to read the linked tweet (above) on the transmission q.

I really wish MEPs had the opportunity to pose questions to someone who had been involved in the R&D side of things rather than the business side of things so their questions could have been answered. 2/5
BUT I want to correct the record bc some news has reported on the committee meeting as if it were entirely abt that, when in fact most MEPs were focused on concerns abt democratic process: public money shd be accounted for in transparent contracts. 3/5
Read 5 tweets
Oct 11, 2022
To sum up today's @Europarl_EN hearing w/@Pfizer on #COVID19 vaccines:

1) member states are furious by the lack of transparency & #SMSgate
2) @AlbertBourla miscalculated that this was something he could skip.
3) The committee is ready to recommend consequences

Summary in 🧵1/
I don't usually do full 🧵 detailing hearings (apologies in advance), but what happened yesterday was pretty extraordinary and I think will be important in setting the course for ongoing future pandemic planning.

You can watch the full hearing here: multimedia.europarl.europa.eu/en/webstreamin… 2/
***First: Where is @AlbertBourla?***

.@SincicMEP sums up the general mood in the room:

"I must say that it is a disgrace that @AlbertBourla is not with us today and an even greater disgrace that he doesn't have any real intention of showing up."
3/
Read 41 tweets
Aug 4, 2022
Pharma is really good at creating narratives with half-truths (or just outright lies) that narrow the policy space to their desired outcome.

So good that even @jacobin- a rare US socialist magazine-has accidentally repeated a few of their greatest hits. A (gentle) correction 🧵1
Let's unpack this:

"The sheer complexity of insulin production makes it financially unviable for generic companies. Thus, instead of generic insulin, we speak of biosimilar insulin — a biosimilar is a biologic drug that is extremely similar but not identical to the original." 2
First, generic insulin markets are 100% financially viable. I hate to be that academic that says "I have a paper on that" but
gh.bmj.com/content/3/5/e0…

We assume a 10% profit margin (which is more than average) & estimate costs at ~$3/vial for NPH + $5 for glargine. V. viable! 3
Read 12 tweets
Jun 1, 2022
Are you a pharma company who just put up a 🏳️‍🌈logo but have not yet announced meaningful efforts to improve the lives of LGBTQ+ people?

To help you really celebrate this #PrideMonth #Pride2022 right here's a🧵of some actionable ideas you can implement this month. (1/11)
Sky high prices for insulin mean that people are rationing and dying because they cannot afford it.
-jamanetwork.com/journals/jamai…
-t1international.com/access-survey/

LGBTQ+ ppl are disproportionately affected bc discrimination-> poverty + job discrimination
williamsinstitute.law.ucla.edu/publications/l… (2/11) Image
1 in 4 teens are forced to leave home after coming out.

Many ppl under 26 are on their parents' health insurance, making coming out even scarier than it already is bc it might mean that you need to find new insurance fast- not easy & $ in the USA (3/11)

lesley.edu/article/the-co…
Read 12 tweets

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