UNMET NEED #2 – in the face of our current opioid crisis, there is a clear and immediate need for a non-opioid, non-addictive, alternative for pain (besides just NSAIDs or acetaminophen).
I know many are working on this.
👉Thoughts on how close we are?
9/
Labs sent. RUQ US done.
Pain now bearable.
I was NPO, felt parched, and a bit lightheaded.
I asked for some IVF which seemed to irritate the nurse.
No indication for IVFs I was told.
Reluctantly - LR started.
Damn pendulum - some IVFs are OK!
10/
At this point, I am convinced I have an obstructed bile duct.
To my amazement, RUQ US was NEGATIVE.
✅CBD 4 mm.
✅No stones.
✅No GB wall thickening.
✅No fluid.
✅Pan labs all normal.
Of course - this only reinforced the impression that I was a drug seeker.
11/
ED doc to his credit, even ordered a CT scan and acknowledged that it was odd that I had severe pain.
Not sure how genuine, but the first pseudo-acknowledgment that my pain was real.
A Multicenter Evaluation of Blood Purification with Seraph 100 Microbind Affinity Blood Filter for the Treatment of Severe COVID-19: A Preliminary Report
I was prepping for a panel discussion with medical students on death and dying. Had to get some thoughts together based on my experience as a military intensivist so I thought I would share.
I’ve experienced my share of death. Of course the typical “taking terminal patients through the dying process” kind of stuff that every internist and intensivist deals with…
I just saw this thread by @MarkHoofnagle and feel compelled to respond to clarify some things.
Disclaimers: I am not an ID expert. I am a Medical Intensivist in the Military. These are not the official views of the DoD. Just my personal opinions. No financial COIs.
I have participated only as a site-AI but I have participated in investigator meetings since the inception of this trial so I have *some* inside knowledge.
2/
First off, this trial was conceived and protocol approved before our very first US case back in February. It is funded by NIAID. Not Gilead. Remdesivir was chosen because of its potential. Not financially motivated.