Atrial and Ventricular Enlargement:
- Both dilation & hypertrophy usually result in chronic pressure and volume overload on the heart muscle
- Pathological hypertrophy & dilation are often accompanied by fibrosis (scarring); can lead to arrhythmias and heart failure.
Right Atrial Abnormality (RAA):
- Overload of RA (dilation/ hypertrophy) may increase P-wave voltage
- Normal P-wave < 2.5 mm amplitude and < 0.12 seconds in width
- Tall, narrow P-waves: characteristic of RAA and can be best seen in II, III, aVF
Causes of RAA:
- Pulmonary disease: asthma, PE, emphysema, bronchitis
- Congenital heart disease: Pulmonary valve stenosis, atrial septal defect, Ebstein's anomaly, malformation of tricuspid valve, tetralogy of Fallot
Left Atrial Abnormality (LAA):
- Normally, the LA depolarizes after the RA
- LA enlargement is associated with prolongation of of total duration of the atrial depolarization (>0.12 sec)
- Can have a distinctive hump or notched appearance
- P-mitrale: Rheumatic heart disease
Left Atrial Abnormality:
- Lead V1 can sometimes show a distinctive biphasic P-wave (small, initial positive deflection followed by a prominent, wide negative deflection)
- Seen in valvular heart disease (AS, AR, MR, MS), HTN, dilated/hypertrophic cardiomyopathy, CAD
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Atrial and Ventricular Enlargement:
- Both dilation & hypertrophy usually result in chronic pressure and volume overload on the heart muscle
- Pathological hypertrophy & dilation are often accompanied by fibrosis (scarring); can lead to arrhythmias and heart failure.
Right Ventricular Hypertrophy:
- Right chest leads show tall R-waves
- R-wave > S-wave in V1 is suggestive; not diagnostic of RVH
- Can see right-axis deviation and T-wave inversions in the right & mid-precordial leads
- RV hypertrophy can lead to variations in repolarization
General Principles:
- Positive deflection: wave of depolarization towards positive pole of that lead
- Negative deflection: wave of depolarization towards negative pole of that lead
- Biphasic deflection: wave of depolarization is perpendicular to a lead
Normal Sinus P-wave:
- Atrial depolarization that marks spontaneous depolarization of pacemakers cells in the right atrium
- Should be negative P-wave in aVR and upright in lead II
- Can communicate 'sinus rhythm with 1:1 AV conduction'
ECG Leads:
- Body act as a conductor of electricity; the recording electrodes in the arms, legs, and chest wall show the differences in voltage (potential) among electrodes
- Different views of the same event leads to different ECG patterns
ECG Limb Leads:
- 6 Limb leads (extremity leads) and 6 chest (precordial)
- 3 bipolar limb leads: I, II, III
- 3 augmented unipolar: aVR, aVL, and aVF
- 6 precordial leads: V1-V6
Conduction System:
- SA node (pacemaker cells) have specialized conduction tissue
- SA node is located in the RA near the opening of the SVC
- Stimulation occurs from right atrium to left atrium
- Simultaneous atrial contractions allows for blood filling into LV and RV
Conduction:
- AV Junction: Located at the base of the inter-atrial septum and extends into the inter-ventricular septum; the proximal portion is the AV node and distal portion is bundle of His
- Left & Right Bundle branches depolarize the myocardium via Purkinje fibers
1) Hypertensive Encephalopathy
- Cerebral edema is induced by markedly elevated blood pressures
- Dysregulation of auto-regulatory capabilities of the brain
- Characterized by headache, irritability, and altered mental status
- Treatment of choice: Nitroprusside/Labetalol
2) Reversible Posterior Leukoencephalopathy Syndrome (PRES)
- MRI may reveal white matter edema in the parito-occipital regions