Atrial and Ventricular Enlargement:
- Both dilation & hypertrophy usually result in chronic pressure and volume overload on the heart muscle
- Pathological hypertrophy & dilation are often accompanied by fibrosis (scarring); can lead to arrhythmias and heart failure.
Right Ventricular Hypertrophy:
- Right chest leads show tall R-waves
- R-wave > S-wave in V1 is suggestive; not diagnostic of RVH
- Can see right-axis deviation and T-wave inversions in the right & mid-precordial leads
- RV hypertrophy can lead to variations in repolarization
Right Ventricular Hypertrophy:
- Factors: congenital heart diseases (pulmonary stenosis, ASD, tetralogy of Fallot, Eisenmenger's syndrome), lung disease (severe pulmonary hypertension)
- Can happen in patients with complete/incomplete RBBB pattern with RA deviation
Left Ventricular Hypertrophy (LVH):
- Normally, LV has a larger mass and is electrically dominant compared to RV
- 2 most important causes: systemic HTN & Aortic stenosis
- 3 major clinical conditions w/ LV overload: Aortic & Mitral Regurgitation, Dilated Cardiomyopathy
LVH Criteria:
- S-wave in V1 & R-wave in V5/V6 ≥ 35-mm (high voltages can be common in athletic or thin, young adults)
- Cornell voltage: S-wave in V3 + R-wave in aVL > 28-mm in men and > 20-mm in women
- R-wave > 11-13 mm in aVL
LVH:
- Strain pattern: ST-T wave changes with distinctively asymmetric appearance with slight ST-segment depression followed by broadly inverted T-wave
- Can see signs of left atrial abnormality (broad P-waves in extremity leads or wide biphasic P-waves)
Biventricular Hypertrophy:
- Present in some cases of severe dilated cardiomyopathy or rheumatic valvular disease
- Should get an ECHO to determine the presence of cardiac chamber enlargement
General Principles:
- Positive deflection: wave of depolarization towards positive pole of that lead
- Negative deflection: wave of depolarization towards negative pole of that lead
- Biphasic deflection: wave of depolarization is perpendicular to a lead
Normal Sinus P-wave:
- Atrial depolarization that marks spontaneous depolarization of pacemakers cells in the right atrium
- Should be negative P-wave in aVR and upright in lead II
- Can communicate 'sinus rhythm with 1:1 AV conduction'
ECG Leads:
- Body act as a conductor of electricity; the recording electrodes in the arms, legs, and chest wall show the differences in voltage (potential) among electrodes
- Different views of the same event leads to different ECG patterns
ECG Limb Leads:
- 6 Limb leads (extremity leads) and 6 chest (precordial)
- 3 bipolar limb leads: I, II, III
- 3 augmented unipolar: aVR, aVL, and aVF
- 6 precordial leads: V1-V6
Conduction System:
- SA node (pacemaker cells) have specialized conduction tissue
- SA node is located in the RA near the opening of the SVC
- Stimulation occurs from right atrium to left atrium
- Simultaneous atrial contractions allows for blood filling into LV and RV
Conduction:
- AV Junction: Located at the base of the inter-atrial septum and extends into the inter-ventricular septum; the proximal portion is the AV node and distal portion is bundle of His
- Left & Right Bundle branches depolarize the myocardium via Purkinje fibers
1) Hypertensive Encephalopathy
- Cerebral edema is induced by markedly elevated blood pressures
- Dysregulation of auto-regulatory capabilities of the brain
- Characterized by headache, irritability, and altered mental status
- Treatment of choice: Nitroprusside/Labetalol
2) Reversible Posterior Leukoencephalopathy Syndrome (PRES)
- MRI may reveal white matter edema in the parito-occipital regions