NextMed.Health - pricey $$$$ in person but streaming live free of charge! Join now:
Direct link to streaming and agenda:
3/ Image
4/ Future applications of AI ImageImageImageImage
5/ AI limitations Image
6/ AI: We don't wanna create chemical weapons, and we don't wanna perpetuate problems of the current medical system -> Do no harm & pay down tech debt ImageImageImageImage
7/ On Web3 in healthcare ImageImage
8/ ChatGPT is just a tip of the iceberg. We need a highly decentralized approach. Image
9/ From web 1 to web 3 ImageImageImage
10/ On decenralized science. Massive transformation is happening in the science space. ImageImage
11/ How o we take AI to decentralized data? Aggregation, mining, reward, interact. True anonymity, not just pseudoanonymity. ImageImageImageImage
12/ Pseudoanonymity -> privacy tech.
Utility vs. privacy.
Tradeoff as you go to the right.

Federated Learning & Split Learning ImageImageImageImage
13/ Every hospital can create local AI, but those are imprecise. (What works on children may not work on elderly. What works on smokers may not work on nonsmokers) -> creating collective intelligence ImageImageImage
14/ ImageImageImage
15/ HealthUX.

Friction in EHR (e.g. patient matching - recognizing correct patient when multiple have the same name)

Decentralized science and AI ImageImageImageImage
16/ More on decentralized society w/ web 3 - see the QR code ImageImage
17/ Surgeon and XR enthusiast @ZGJR is now on stage at @NextMedHealth. Join livestream here: ImageImage
18/ Augmented Relity (AR) - Mixed reality (MR) - Virtual reality (VR)


Multi-user experience from different geographical locations ImageImageImageImage
19/ Learn how to diagnose etc. from extended reality. Multiuser training.

Sensory integration including haptics

Cost has been decreasing ImageImageImageImage
20/ Platform: must be multi-player, scalable, AI powered, cost-effective

Haptics glove helps you feel what you're touching to make it more real. ImageImageImageImage
21/ VR: can smell (e.g. while learning to make pizza).

Strong potential: PTSD and smelling powder

Manipulate data real time in 3D

Improving flow and experience in a surgery ImageImageImageImage
22/ Bringing anatomically correct images to EMR Image
23/ Blue pill or red pill? ;) Image
24/ Q (@daniel_kraft): Who can be a surgeon w/ the new technology?🤔

A (@ZGJR): Technology can bring education to anywhere anytime in a cost effective way to anywhere in the world... Image
25/ 🎶Highway to hell ➡️ Highway to heal. @acdc music w/ lyrics rewritten for medical field🩺🎸💡 ImageImage
26/ Chris Wigley on genomics

Sequenced kiddo Jessica (4yo) and both parents to get an effective treatment. ImageImageImageImage
27/ Population health study. Clinical reasons to be using whole genome studies: many patients not diagnosed through other means ImageImageImageImage
28/ Massive proof of concept study for genomics in healthcare

Numerous partners ImageImage
29/ Whole genome sequencing. Green: piloting, trying to bring into clinic. Scicence -> pilots -> innovation -> clinical care Image
30/ Productivity challenges. Appmnts can be reduced. Finding right therapeutics for cancer patients.

Like acquarium: study but don't take it out.

Only valuable when joined w/ other modalities.

Scanning & digitizing data from cancer patients -> the largest dataset of its kind ImageImageImage
31/ Kiddo w/ inconclusive tests. Genom determined that his tumor was benign. Image
32/ They have the lead scientists to lead the discoveries ImageImage
33/ Lifelong relationship w/ the genome: how can that accelerate the right treatment?


Teenager: mental health

Later: neurodegenerative diseases Image
34/ Genomics England to transform lives on scales and demonstrate the concept Image
35/ Andrew Hessel on Synthetic Biology: Rewriting Life.

= intersection of life science, computation and automation ImageImage
36/ DNA sequencing cost is outpacing Moore's Law ImageImageImageImage
27/ Identify which dog has been pooping on your lawn 😂💩🐕‍🦺 Image
28/ Numerous applications: anything that touches life, including degradable plastics.... ImageImage
29/ Positive feedback loop.

AI tools to design proteins.

Labs are becoming automated. ImageImageImageImage
40/ Protein engineering.

Can grow cells on chips and train it to play pong.

Will be able to engineer vectors and viruses.

Kill cancer cell... -> treat cancel in an individualized way

Cancer vaccines for patients. ImageImageImageImage
41/ We'll need bigger investment in biosecurity.


Can we stop aging, or even become immortal? Image
42/ intersection w/ #space (cc @OACspace) Image
43/ Will our bedrooms look like this in 20-30 yrs? Image
44/ On new frontiers in women's health. Female animals and humans were not included in clinical trieals until quite recently. It's also a funding problem. ImageImageImageImage
45/ #Ovaries age 2.5x faster than the rest of the body -> puts #women in distinct disadvantage. Ovarian health is very important for overall women health. Image
46/ 1000 eggs are lost month, 1 of which may or may not get fertilized.

Line between puberty and menopause: if we can change theat -> can change how women age -> @OvivaTx

Hormonal changes associated w/ #menopause speed up cellular aging by 6% ImageImageImageImage
47/ Women w/ later menopause tend to live longer. Image
48/ Eternal fertility in naked mole rats Image
49/ #AMH

Regulates how often and how many eggs released to maturation pathway

-> can regulate the pace at which we deplete the ovarian reserves? Image
50/ Possible fertility and IFV help.

Can double # (ovulated?) eggs w/o reducing quality

Validating - lots of info we don't know. Humans aren't rodents. ImageImageImageImage
51/ Goals: Learn more about women's (ovarian) health. Raise awareness. Uncover unanswered questions. Train docs better.

Ultimately: give women choice!

Learn more on @OvivaTx website. Image
52/ Mariya Filipova on Systemic Health: healthy patient outcomes communities

Do you think about dentist when we mention overall health? Oral health is overall health! Related to many other health aspects.

Untreated oral health issues -> higher risk of dementia & cognit. decline ImageImageImageImage
53/ Neither painkillers nor antibiotics treat the underlying issue.

🦷Also equity issue: more likely to have

Dental care is outpacing the growth of healthcare costs ImageImageImageImage
54/ Access to florinated water

Toothbrushes: electric prototype from 1937 similar to today's toothbrushes

Patient experiences and outcomes haven't changed much ImageImageImageImage
55/ Providing funding to companies that improve link dental care and link it to overall health.

@vVardisofficial: Peptide that regenerates enamel.

Future: instead of drilling & filling may be able to ("rebuild"?) ImageImageImageImage
56/ Accelerator w/o giving up equity Image
57/ 🦷innovative companies examples:

Saliva-based diagnostics to screen for dental cancer early

Future: Connecting medical & dental teams. Coordinated & integrated treatment plan. Image
58/ COmpany w/ enamel regenerating product weren't initially able to get reimbursement b/c there was no code. Recently passed new CDT code. Need collaboration b/w investors, companies and regulators. Their accelerator is accepting applicatoins! ImageImageImageImage
59/ Session 4: Transforming tech & patient voice into empathy, impact & access.

@lucienengelen: "From What's New, to How To" Image
60/ Don't fix the hole, reach out to the main tap! ImageImageImageImage
61/ By 2035 we'll have a problem in healthcare Image
62/ Do we add digital? Or digital first?

It's about user interface, yourself.

If possible, do it yourself, at home, digitally. ImageImage
63/ Possible new Moore's Law: doubling intelligence in the universe ImageImageImageImage
64/ World's first autonomous robot Image
65/ "How are you doing?" - "Great! Slept well & have a great EKG!" ImageImageImageImage
66/ ImageImageImage
67/ Consumer is awakening. The consumer is your patient.

Why aren't we utilizing supermarkets? -> Healthcare meets retail. ImageImageImageImage
68/ Maybe we'll have new tech @ retail places ImageImageImageImage
69/ Healthcare is next! ImageImageImage
70/ Non-healthcare players in healthcare ImageImageImageImage
71/ Every citizen wil have own data. Better diagnostic and treatment. ImageImageImageImage
72/ Healthcare: delocalized, democratized, digital ImageImageImage
73/ Joyce de Ruiter: Patients Included: Agility & Resilience in Times of Change ImageImageImageImage
74/ Wow - thank you Joyce de Ruiter for sharing on your rare disease experience with Usher syndrom related to loss of both vision and hearing ImageImageImageImage
75/ A brief conversation can make a huge difference to a patient.

Always choose words of empowerment.

Wow, Joyce de Ruiter - such an overachiever and an inspirer despite of your diagnosis! ImageImageImageImage
76/ PDOH: "Political determinants of health"

Alister Martin: "At the intersection of healthcare, policy & civic engagement" ImageImage
77/ DYI: Voter registration is legal in healthcare settings (as a proof of residency in Massachusets)

"Why aren't you registered to vote?" - "Noone has ever asked me" ImageImageImageImage
78/ Low voter turnout & low life expectancy are correlated ImageImageImageImage
79/ Vote to have perspectives included in politics and when important decisions are being made ImageImageImageImage
80/ Doctor's questions: Do you smoke? Do you drink? Are you registered to vote?

Posters and discharge papers helping patients to vote.

Patient registered to vote -> got home, and also helped her family to register to vote. ImageImageImageImage
81/ They helped 80k patients to register to vote, w/ turnout 85% (higher than general population of 66.8%) Most pronounced on low propensity voters. ImageImageImage
82/ Voting = SDOH!

They helped w/ HHS & VA

Upcoming 2024 registration -> opportunity to get patients involved in voting! cc @poppy_northcutt ImageImage
83/ Physicians voted 9% lower than general population Image
84/ Healthcare workers can help created democracy and increase # registered voters and voter turnout. More info: Image
85/ Magical interlude w/ a Robert Strong - commedian & magician


Power of Story w/ Dave Zaboski ImageImageImage
86/ @Deloitte folks on stage: Bori Kheyn-Kyeyfets & Simon Gisby on "Platforms & The Reassembly of Care"

Sick care -> health care -> wellness (well care) ImageImage
87/ Ecosystem focused on us: my healthcare meets

Covid times: we turned healthcare workers into gig workers who can work from another locations!

Platforms will take us from fragmentation to reassembly ImageImageImageImage
88/ We'll need a "platform mindset": navigating patients - members - consumers

Fee for service -> value based care

Health systems, med tech, pharma: point solutioning companies are not driving this transformation

$40B flowing VCs -> different diseases => to merge & aggregate ImageImageImage
89/ How do you balance personalization?

Retina: unique identifier. Who owns "Clear"? Are we willing to give up data w/o knowing who owns the data to save a few min and not to take off our shoes at the airport? ImageImage
90/ Andrea Kates on Finding Your Next ImageImageImageImage
91/ There is no try. Only do. ☯️

Take concrete steps towards game changing actions. ImageImageImageImage
92/ Get to the next concrete steps! ImageImage
93/ Jemie Metzl: The promise and peril of human genome editing.

Author of Hacking Darwin: Genetic Engineering & the Future of Humanity.

Member, WHO expert advisory committee on Human Genome Edicting ImageImageImage
94/ Jamie Metzl predicted that gene editing would happen soon and that it would happen in China ImageImageImageImage
95/ Estimating 13 new genes therapies to be approved this year (2023)

Photo from 3rd international summit on gene editing w/ Victoria Gray - see the attached quote!

These technologies: unlimited potential to "do good" ImageImageImageImage
96/ Promises:
- Heritable diseases
- Times when we'll be able to treat everything
- Even at or before pre-implanted embryo
- Therapy vs. enhancement: part of the same continuum.
- Expecting discussions: what's ok?
- Living in space? Athletics? ImageImage
97/ Real dangers, fears, origins of covid and book tips ImageImageImageImage
98/ Interconnected ecosystems.

We each have a role.

Let's do what we're doing as ethically as possible. ImageImageImageImage
99/ Med scrubs for attendees! Also encouraging to install app for tomorrow. ImageImage
100/ Closing keynote from day 1: by legend Leroy Hood Md PhD: "The transition from genomics to phenomics in precision population health"

Why health?

Health started w/ the Greeks.

Using data-driven systems

Blood = window into wellness & disease: Molecules concentration changes ImageImageImage
101/ 1M person project over 10 yrs

1. Arivale (body) company he co-started

2. Partnering w/ Posit (brain)

3. Gut microbiome

Nearly 30 studies on wellness ImageImageImage
103/ For most chronic diagnoses (cancer or diabetes): we have subtypes, then we can define nature of the subtype trajectory.

Health: welness - transition - disease ImageImageImage
104/ Partners Image
105/ Will generate at least 1000x more data than initially

Recommendations how to optimize;



Whole genome analysis ImageImageImageImage
106/ 2 knowledge graphs:
1. Google (50B nodes such as genes, proteins, gene diseases)
2. Spoke: Smaller (27M) but more details

Creating a digital twin for type 2 diabetes

Context for hyperscale AI

Mechanistic / causal ImageImageImage
107/ How to persuade HCP, payer, politician, patient to buy into this?

Solution: prediction & prevention is going to save $Ts

Medical schools skeptical in trying new things.

Innovative healthcare 20module 1yr course for hs students

Upcoming book & documentary on wellness ImageImageImageImage

• • •

Missing some Tweet in this thread? You can try to force a refresh

Keep Current with Martina Truche 🚀 🩺

Martina Truche 🚀 🩺 Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!


Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!


0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy


3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!