Pankti Mehta Profile picture
Apr 21, 2023 10 tweets 5 min read Read on X
😣Patient: "All my joints are painful & swollen!"😣

👩‍⚕️But when you examine the patient, you don't find any joint swelling

How to approach this scenario? 🤷

#MedTwitter #RheumTwitter #MedEd 🧵🧵🧵

(1/10) Image
Now there are two possibilities

1️⃣ There was a joint swelling which is no longer there

OR

2️⃣ There was no joint swelling to begin with

(2/10)
Let's start with the first one– there was indeed joint swelling which is no longer there

That means we are dealing with

☝️ An episodic inflammatory disease
✌️ Drug modified disease

(3/10)
☝️Episodic inflammatory diseases

💭 Of

🔹#Gout
🔹CPPD
🔹Palindromic #rheumatoid arthritis
🔹Autoinflammatory syndromes
🔹Spondyloarthritis (especially reactive)

(4/10)
✌️ Drug-modified disease

Any inflammatory arthritis can be modified by the use of

🔹Steorids 👿
🔹DMARDs💊
🔹Complementary & alternative drugs 👿👿👿! (Very important)

So take that history well and check all records !

(5/10)
Now, let's move to scenario no.
2️⃣ There was no joint swelling to begin with

This raises 2 questions

☝️are we dealing with #arthritis?
✌️or is it something else?

(6/10)
☝️ So, what kinds of arthritis may not have joint swelling?

Simple- The ones that are non inflammatory!

💭 of

Osteoarthritis

(7/10)
✌️is it even arthritis or something else?

Confirm if the pain is restricted to the joints or not?

Regional/diffuse pain could be related to

🔹Fibromyalgia
🔹Hypermobility disorders
🔹Myalgia
🔹Bone pains
🔹Osteomalacia
🔹Neurologic pain
🔹Soft tissue rheumatism

(8/10)
Also, some diseases may only have polyarthralgia

🔹Lupus
🔹Sjogren
🔹Post Viral syndromes
🔹Hypothyroidism

(9/10)
In summary,

✅Joint pain without ❎swelling

💭 of
🔹Episodic #arthritis
🔹Drug modified arthritis
🔹Non inflammatory arthritis
🔹Regional/widespread #pain syndromes
🔹Systemic diseases with polyarthralgia!

(10/10)

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More from @PanktiMehta24

Jul 10
How to approach a patient with #angioedema? 🧐 🧵

#MedTwitter

(1/7) Image
♦️There are two broad mechanisms of angioedema

1️⃣ Histamine mediated or #allergy 🤧
2️⃣ Bradykinin mediated 🥵

The management depends on the underlying mechanism !

Also before anything, secure the AIRWAY if needed 🫁

(2/7)
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✏️What are the possible etiologies ?
🔹Allergic 🤧
🔹Drugs 💊
🔹Hereditary 🧬
🔹Acquired
- lymphoproliferative disease➡️ excess C1
-autoimmune diseases ➡️ antibodies against C1inh

(3/7)
Read 7 tweets
Jul 4
Facial rashes that look like lupus but are not ! 🧵🦋

1. Rosacea 🥵
🔹Look for telangiectasia
🔹Involvement of the nasolabial folds 🔹Flushing with spicy foods, heat, & sun exposure

#MedTwitter #RheumTwitter
Image
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2. Seborrheic dermatitis

🔹Yellowish scales
🔹 Involvement of the nasolabial folds, eyebrows & scalp Image
3. Dermatomyositis

🔹Involvement of the nasolabial folds
🔹Other rashes like heliotrope, gottron's etc
🔹Systemic features Image
Read 5 tweets
Jun 15, 2023
🫁How to interpret pulmonary function tests ??🫁

I'm not a pulmonologist but have to deal with a fair share ILDs,
here's a simple approach useful in the clinic especially for non pulmonary specialists

(1/7)

#MedTwitter #RheumTwitter #MedEd Image
1️⃣Is the test valid?

You need to check for three things

🌬️ Effort
✅The time volume curve forms a plateau in 1-2 seconds
✅ sustained expiration for 6 seconds!

(2/7) Image
➰Flow loops

✅ for artefacts/abnormalities 📷⤵️

(3/7) Image
Read 8 tweets
Jun 13, 2023
🔹Relapsing Polychondritis🔹

Important takeaways from an excellent presentation by @Lupusreference @eular_org #EULAR2023

#MedTwitter #RheumTwitter
🔹Rare disease
🔹Middle aged adults
🔹No♀️ predominance

👂👂👂👂
It's typically characterized by:
🥵Red/swollen
👂Spares the lobule
🤕Painful
⏳lasts >48 hrs
❌ ear discharge (infection)
❌ necrosis/purpura (CAPS)

📷⤵️Prone to erroneous diagnosis!! ImageImage
Once 👂chondritis is confirmed, rule out mimics! Image
Read 11 tweets
Jun 6, 2023
Doctor: Where is the pain?

Patient: Pain pain everywhere!

❔How do we approach a patient with multiple joint pains❔

(1/12)
#polyarthritis #MedTwitter #MedEd #RheumTwitter Image
1️⃣ Is it polyarthritis?

First, you want to make sure it's polyarthritis - multiple (>4 joints) pain WITH SWELLING

& NOT 🚫

🔹Polyarthralgia⏩ pain WITHOUT swelling
🔹Widespread pain
🔹Myalgia
🔹Bone pain
🔹Neuropathic pain

Let's deal with polyarthritis ⏬

(2/12)
2️⃣ Is it acute or chronic??

Acute<6 weeks

🔹 Infections- gonococcal, infective endocarditis, rheumatic fever, lyme disease, viral

🔹Elderly RA, ANCA vasculitis, paraneoplastic

(3/12)

#MedTwitter
Read 12 tweets
Jun 5, 2023
It's #WorldEnvironmentDay2023 & I thought why not discuss the influence of air pollution🏭 on various rheumatic diseases

The association of 🏭 is obvious with lung diseases, malignancies & skin problems

But, we have to understand that the effects are deeper than that😦
Particulate matter (PM10) is inhaled & affects the upper bronchi ⏩ local inflammation

Fine & ultrafine PM reach the alveoli & circulation ⏩ systemic effects

Levels of inflammatory markers ∝ exposure to 🏭

pubmed.ncbi.nlm.nih.gov/19687019/

pubmed.ncbi.nlm.nih.gov/33470401/ ImageImage
Does it increase the risk of disease development?

Yes!

In a study from Italy, exposure to PM 10 increased the risk of RA & other immune mediated diseases

pubmed.ncbi.nlm.nih.gov/35292563/aa Image
Read 6 tweets

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