Nirmal Pandey MD DM Neurologist Profile picture
May 7, 2023 11 tweets 47 min read Read on X
We were consulted for a 2nd opinion.
30F. D1. Deep dog bite L cheek while tending fields. Multiple others bitten. Dog was killed the same day by villagers. #NeuroTwitter #MedTwitter #IDtwitter #NeuroRad #Neurology Image
D2. Visited PHC.
Prescribed PVRV (Abhayrab) D2, D5, D8, D13. NO RIG given. Image
D16. Fever, uncontrolled vomiting.
D20: admitted. Rx as sepsis.
D22 discharged. No hydro/aerophobia.
D23. Drowsy/unresponsive/taking orally food/water. Readmitted.
NB: Aerophobia is seen in ~50%, Hydrophobia in 10-15% Image
D23. CEMR done👇 DWI/ADC/GRE/T1+C unremarkable. Became dull, mouth frothing. Ventilated. Virus migrate retrogradely @ up to 250 mm/d through axoplasm > DRG of cord > diencephalon, hippocampus, brainstem. T2/Flair 👇 ImageImage
D24: CSF
~60,000 die per yr, probably more, as many cases go unreported. RIG is usually not prescribed as often it should be. Once you see a rabies patient you will never miss on the RIG. Image
When I was doing my residency, at LKO railway station I was bitten in my ankle by a huge sewer rat. I washed it thoroughly. I taxied back to the hospital & got both RIG & ARV knowing fully well that rats are not carriers. THAT should be the PANIC when deeply bitten by Dogs.

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More from @nirmalregency

May 12
Blink & miss.
57♀. T2DM. Referred for evaluation of possible partial right 3rd cranial nerve palsy of 2 days.
Can we pick up the culprit?
MR brain☞ DWI/ADC👇.
T2/T1 in 🧵
(1/13) Image
MR brain T2/T1 👇
(2/13) Image
What do we see?
(3/13)
Read 15 tweets
Mar 31
45♀. 45Kg.
1Y. Gradually↑: Unable to get up from ground. B/L hand tremors.
LE weaker > UE.
Lost a few kilos.
Darkening of skin, ↑ from her previous color👇
?clubbing.
Flushing of palms.
DTRs ↓
#neurotwitter #NeuroX #MedTwitter #MedX #Neurology #FOAMmed
A 🧵 Image
She had come w/ some investigations done over past 6M.
HIV/HCV/HBsAg -ve.
CBC/LFT/KFT N (multiple).
TSH 7.4 (Ref: 1-5).
ANA -ve.
NCS: 👇 Image
CXR: 🆗
She also had an USG abdomen done 👇
Abdominal lymph node CT guided biopsy: non-specific, TB GeneXpert -ve. (We are TB predominant in our part).
Ascitic fluid was transudative. Image
Read 13 tweets
Feb 18
15 ♀
Very peculiar.
Late December. She was taking ↑ than usual time to come out of bathroom. Knocked. No response. Door broken. Unconscious, drooling, naked. This scenario is not so uncommon for us clinicians of North India.
#neurotwitter #NeuroX #MedTwitter #MedX #FOAMed
🧵 Image
Taken to a nearby hospital. ↑ restless & agitation.
“I cannot see” repeating like a parrot.
Came to us in this state ☞ 8 hours.
Restrained. Sedated.
CEMR brain < 24 hrs from onset.
Faint b/l occipital cortical DWI brightness w/ no definite restriction. No enhancement. DWI👇 Image
Faint T2 (not shown) & Flair b/l occipital gyral swelling👇
No Gad enhancement (not shown). Image
Read 16 tweets
Sep 24, 2023
Interesting #Neurology #Pediatrics cases. 🧵
When uncommon cases come, they come in pairs.
Case 1: 8♂. AFI X 5D. Scrub typhus +ve.
AKI. RRT X 3 sessions.
Developed seizures on D8.
MR 👇 #neurotwitter #NeuroX #MedTwitter #MedX #neuroradiology #MRI Image
Case 1: There was no Gad enhancement or restricted diffusion.
Possibilities?
Case 2: 2♀. AFI X 6D. AMS.
MR brain on arrival NORMAL (not shown).
AKI. RRT X 3 sessions.
Developed seizures on D12. MR (D12) 👇 Image
Read 12 tweets
Apr 2, 2023
Learning through mistakes.
(1/11) 38F. 90kg. No PMH. Fever x 3-4D ☞ body pains.
D6: frequent seizures. Multiple ASMs.
D7: CT head + CSF WNL.
D11: MR brain WNL (not shown).
D13: Repeat CSF WNL.
D16: Repeat MR Brain👇 faint b/l medial temporal hyperintensities.
Acyclovir ✅
(2/11) D19: shifted here.
Seizures ++, mostly over face w/ partial preserved consciousness.
Intubated. 4 ASMs ☞ Ketamine bolus ☞ infusion.
D19: IVIG + IV MPS also started.
Repeat CSF: routine normal. CSF BioFire -ve, including HSV. Acyclovir stopped.
(3/11) CSF autoimmune encephalitis panel -ve👇Serum paraneoplastic antibody panel -ve 👇
Read 16 tweets

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