Discover and read the best of Twitter Threads about #IDtwitter
Most recents (24)
A #dermtwitter #tweetorial on the skin manifestations of:
SYPHILIS!
#MedEd #FOAMEd #medtwitter #syphilis @VisualDx
pc: en.wikipedia.org/wiki/Treponema…
1/
SYPHILIS!
#MedEd #FOAMEd #medtwitter #syphilis @VisualDx
pc: en.wikipedia.org/wiki/Treponema…
1/
Let's go back to the basics. Syphilis is from an infection by the bacterium Treponema pallidum. Usually spread by sexual means, syphilis has three main stages of disease.
Primary infection usually presents as a papule that turns into a painless ulcer called a chancre.
2/
Primary infection usually presents as a papule that turns into a painless ulcer called a chancre.
2/
Time from inoculation to chancre usually is 10-90 days (21 days is most typical).
There is a rare variant where the patient can get many smaller ulcerations, which is called Follman balanitis.
3/
There is a rare variant where the patient can get many smaller ulcerations, which is called Follman balanitis.
3/
A 31-YO♂️, #sexually active with 2♂️partners in the previous month: 8 days before redness of the R eye, an itchy perianal rash & rectal pain; scattered, tender, shallow ulcers & pustules on chest (A), abdomen (B), back (C) & perianal (D)
1/9
nej.md/44ILgLy
#proctology
1/9
nej.md/44ILgLy
#proctology
PCR from the perianal vesicel:➕for nonvariola orthopoxvirus DNA.
Species-specific PCR: ➕for #mpox virus, clade II.
The patient reported a new rash with numerous ulcer on his chest, abdomen, and back
MPOX (formerly known as #monkeypox)
2/9
#MolBiol #virology
Species-specific PCR: ➕for #mpox virus, clade II.
The patient reported a new rash with numerous ulcer on his chest, abdomen, and back
MPOX (formerly known as #monkeypox)
2/9
#MolBiol #virology
During the next 2 days, the patient took tecovirimat & reported redness & discomfort of the right eye and become painful
He had learned that mpox had been diagnosed in one of his #sexual partners from the previous month.
Likely MPOX CONJUNTIVITIS
3/9
#ophthalmology #IDtwitter
He had learned that mpox had been diagnosed in one of his #sexual partners from the previous month.
Likely MPOX CONJUNTIVITIS
3/9
#ophthalmology #IDtwitter
We were consulted for a 2nd opinion.
30F. D1. Deep dog bite L cheek while tending fields. Multiple others bitten. Dog was killed the same day by villagers. #NeuroTwitter #MedTwitter #IDtwitter #NeuroRad #Neurology
30F. D1. Deep dog bite L cheek while tending fields. Multiple others bitten. Dog was killed the same day by villagers. #NeuroTwitter #MedTwitter #IDtwitter #NeuroRad #Neurology
D2. Visited PHC.
Prescribed PVRV (Abhayrab) D2, D5, D8, D13. NO RIG given.
Prescribed PVRV (Abhayrab) D2, D5, D8, D13. NO RIG given.
D16. Fever, uncontrolled vomiting.
D20: admitted. Rx as sepsis.
D22 discharged. No hydro/aerophobia.
D23. Drowsy/unresponsive/taking orally food/water. Readmitted.
NB: Aerophobia is seen in ~50%, Hydrophobia in 10-15%
D20: admitted. Rx as sepsis.
D22 discharged. No hydro/aerophobia.
D23. Drowsy/unresponsive/taking orally food/water. Readmitted.
NB: Aerophobia is seen in ~50%, Hydrophobia in 10-15%
1/ One of the privileges and duties of becoming a full professor is to write letters of evaluation for junior faculty in the promotions process at outside institutions. I give these a lot of thought and have completed 6-8 per year in the past three years.
2/ Usually, I receive an e-mail inquiry from an outside departmental administrator. When I agree to the evaluation, I am sent a promotion package prepared by the faculty member as well as a letter/document with promotions criteria by the host institution.
3/ I am increasingly troubled by requests for comparative evaluations:
Here's an example from one request letter (redactions to maintain anonymity):
• Estimate their (Dr. X's) standing in the field and compare them with other faculty of roughly the same cohort.
Here's an example from one request letter (redactions to maintain anonymity):
• Estimate their (Dr. X's) standing in the field and compare them with other faculty of roughly the same cohort.
I am going to write part of my (unfinished) story about the K to R transition as a woman in medicine and physician scientist in a multi-disciplinary research space in a tumultuous time. I am oversharing to encourage others in a similar 🚤#medtwitter #IDTwitter #AIMedEd. /1 of 20
I study #drug #allergy. It was the inferior antibiotic choices we made for people with vague antibiotic allergies during my residency @MGHMedicine @mghmedres that initially gave me the idea. Too often the allergy lists were impeding clinical care. /2 of 20
I hypothesized that drug allergies were a problem -- that penicillin allergies alone were linked to important antibiotic stewardship and public health outcomes. I set off to prove this, and address the burden of unclear drug allergies across populations. /3 of 20
An 85-YO in rural Mississippi: months of tender, erythematous plaques & edema on bilateral hands extending to the elbows & on feet extending below the knees with significant pain
🔬skin granulomatous inflammation & numerous AFB
Mycobacterial🧫:➖
1/19
#IDtwitter #dermatology
🔬skin granulomatous inflammation & numerous AFB
Mycobacterial🧫:➖
1/19
#IDtwitter #dermatology
A repeat skin extensive granulomatous inflammation (A), with Ziehl-Neelsen stain clusters of acid-fast bacilli throughout the dermis (B).
Kinyoun stain >9 AFB/high-power field (C & D).
2/19
DOI: doi.org/10.1128/jcm.00…
#dermpath #microbiology
Kinyoun stain >9 AFB/high-power field (C & D).
2/19
DOI: doi.org/10.1128/jcm.00…
#dermpath #microbiology
Molecular identification: 100% identity to multiple Mycobacterium leprae
BORDERLINE LEPROMATOUS LEPROSY WITH REVERSAL REACTION
3/19
#MedTwitter #MolBiol
BORDERLINE LEPROMATOUS LEPROSY WITH REVERSAL REACTION
3/19
#MedTwitter #MolBiol
Another gem from IDWeek 2022
Increased incidence of colorectal cancer in Veteran Health Administration hospital patients with pyogenic liver abscess
#IDTwitter
Increased incidence of colorectal cancer in Veteran Health Administration hospital patients with pyogenic liver abscess
#IDTwitter
The rationale and the lit review
Methodology:
Just got done presenting at the 31st Annual Clinical Update in Geriatric Medicine, put on by @AHNtoday and @UPMC. Awesome attendees, as usual!
Was asked to talk about "Controversies in Antimicrobial Therapy"
Figured would share here.
#IDTwitter #MedTwitter
🧵
1/
Was asked to talk about "Controversies in Antimicrobial Therapy"
Figured would share here.
#IDTwitter #MedTwitter
🧵
1/
With a Geriatric audience, had to take the opportunity to focus first on the urine.
But also get into SSTI, Bactrim for Group A strep, if you need IV antibiotics for Lyme, dental prophylaxis for prosthetic joints, and duration of therapy.
First up - does +UA/UCx=UTI?
2/
But also get into SSTI, Bactrim for Group A strep, if you need IV antibiotics for Lyme, dental prophylaxis for prosthetic joints, and duration of therapy.
First up - does +UA/UCx=UTI?
2/
Emphatic NO on that one.
Need SYMPTOMS to diagnose a UTI.
I tell patients they need to tell us, we can't tell them.
Positive UCx without symptoms = asymptomatic bacteriuria.
3/
Need SYMPTOMS to diagnose a UTI.
I tell patients they need to tell us, we can't tell them.
Positive UCx without symptoms = asymptomatic bacteriuria.
3/
An otherwise healthy 8 yr girl presents with a 2wk h/o asympt skin eruption. A wk before the onset, she had experienced mild fever, sore throat, & coryza for which she received symp Tx without any significant sequelae.
Guess what folks..!
#MedTwitter #idtwitter #MedEd #FOAMed
Guess what folks..!
#MedTwitter #idtwitter #MedEd #FOAMed
-A h/o similar complaints was also elicited in some of her school friends
-The lesions were not associated with any atopic diathesis, preceding inflammatory dermatoses, drug intake, or suggestive systemic finding.
-The lesions were not associated with any atopic diathesis, preceding inflammatory dermatoses, drug intake, or suggestive systemic finding.
-O/E, multiple discrete hypopigmented macules & patches of varying sizes (0.5-1.5 cm) without any surface change were seen to be distributed symmetrically involving the dorsal & ventral aspects of bilateral lower limbs
#Paxlovid effect on reducing #COVID19 hospitalizations in vaccinated population finally revealed to the public by FDA. #IDTwitter
0.9% (3/317) paxlovid vs. 2.2% (7/314) placebo
fda.gov/media/166197/d…
0.9% (3/317) paxlovid vs. 2.2% (7/314) placebo
fda.gov/media/166197/d…
The relative risk reduction (RRR) of #covid19-related hospitalization was 57.5% (95%CI, -63% to 89%) with #Paxlovid in vaccinated high risk population.
Will point out that the the Hazard Ratio is also 58% for $1 of #metformin.
Will point out that the the Hazard Ratio is also 58% for $1 of #metformin.
Some very interesting dev in the Tx regimens for #TB especially the common rifampicin susceptible TB
@MoHFW_INDIA @DHFWKA @ICMRDELHI @StopTB @UNICEF @paimadhu
#MedTwitter #idtwitter
The imp points 👇
@MoHFW_INDIA @DHFWKA @ICMRDELHI @StopTB @UNICEF @paimadhu
#MedTwitter #idtwitter
The imp points 👇
There were 4strategy groups with diff initial regimens; noninferiority was assessed in the 2 strategy groups with complete enrollment, which had initial regimens of high-dose RIF–linezolid & bedaquiline–linezolid (each with INH, PZA,& ETH).
-The primary outcome was a composite of death, ongoing treatment, or active disease at week 96.
➡️AMINOGLYCOSIDES
Breakpoints for gentamicin, tobramycin, and amikacin are based on population distributions of various species, PK/PD target attainment analyses with an end point of net bacterial stasis and limited clinical data.
Breakpoints for gentamicin, tobramycin, and amikacin are based on population distributions of various species, PK/PD target attainment analyses with an end point of net bacterial stasis and limited clinical data.
Clinical outcomes data for aminoglycosides as MONOtherapy for systemic infections are limited and have resulted in worse treatment outcomes (for infections outside of the urinary tract) compared with other therapies.
A 44-YO♂️, stayed in a rural cottage of France 2 weeks previously: cramping upper abdominal pain with watery diarrhea.
He had passed what he thought were worms in his feces
Eosinophilia
1/6
doi.org/10.1093/cid/ci…
#GITwitter #IDtwitter #microbiology
He had passed what he thought were worms in his feces
Eosinophilia
1/6
doi.org/10.1093/cid/ci…
#GITwitter #IDtwitter #microbiology
The specimens: identified as the larvae of the drone fly, Eristalis tenax
These larvae are 2.5–3 cm in length; the posterior tube gives them the name of “rat-tailed maggots”
INTESTINAL MYASIS CAUSED BY ERISTALIS TENAX LARVA
2/6
doi.org/10.1093/cid/ci…
#parasites #GIPath #Doctor
These larvae are 2.5–3 cm in length; the posterior tube gives them the name of “rat-tailed maggots”
INTESTINAL MYASIS CAUSED BY ERISTALIS TENAX LARVA
2/6
doi.org/10.1093/cid/ci…
#parasites #GIPath #Doctor
Myiasis caused by E. tenax:
✔️rare but have been
✔️reported from various countries including Europe
✔️most often intestinal myiasis, but cases of infestation of the nasal cavity, urinary tract, and vagina have been described.
3/6
#Doctor #MedStudentTwitter
✔️rare but have been
✔️reported from various countries including Europe
✔️most often intestinal myiasis, but cases of infestation of the nasal cavity, urinary tract, and vagina have been described.
3/6
#Doctor #MedStudentTwitter
3 años ♀️, padre con lesiones cutáneas similares: lesiones cutáneas polimorfas localizadas en los glúteos, con elementos papulares, vesiculares y pustulosos umbilicados
1/13
🖊️M Roguera y col. @hgermanstrias @aepediatria
DOI: 10.1016/j.anpedi.2022.09.006
#pediatria #infecciosas
1/13
🖊️M Roguera y col. @hgermanstrias @aepediatria
DOI: 10.1016/j.anpedi.2022.09.006
#pediatria #infecciosas
@hgermanstrias @aepediatria Se confirmó en el padre la infección por virus de la viruela del mono (MPXV).
PCR de líquido vesicular de las lesiones:➕para MPXV.
VIRUELA DEL MONO (Mpox)
2/13
#MolBiol #virology #virología
PCR de líquido vesicular de las lesiones:➕para MPXV.
VIRUELA DEL MONO (Mpox)
2/13
#MolBiol #virology #virología
@hgermanstrias @aepediatria Se realizó aislamiento de contacto y secreciones respiratorias (aérea y gotas) en el domicilio hasta la curación completa de las lesiones cutáneas (a los 10 días de evolución).
No hubo complicaciones ni nuevas lesiones en el seguimiento.
3/12
#IDtwitter #microbiología
No hubo complicaciones ni nuevas lesiones en el seguimiento.
3/12
#IDtwitter #microbiología
A 26-YO♂️ no #sexual contacts other than with his male partner: 6-day of fever, malaise, a swollen parotid gland, & ulcerative lesion on the ipsilateral lower lip.
Mild lymphopenia
⬆️GGT & CRP
1/6
doi.org/10.1016/S0140-…
#IDtwitter #dermatology #EarNoseThroat
Mild lymphopenia
⬆️GGT & CRP
1/6
doi.org/10.1016/S0140-…
#IDtwitter #dermatology #EarNoseThroat
PCRs on the throat & ulcer swabs:➕for human #monkeypox (hMPX)
Genomic sequencing: clade IIb variant clustering within the current international mpox virus outbreak
PAROTIDITIS CAUSED BY hMPX virus
2/6
#sexually #maxillofacial #microbiology
Genomic sequencing: clade IIb variant clustering within the current international mpox virus outbreak
PAROTIDITIS CAUSED BY hMPX virus
2/6
#sexually #maxillofacial #microbiology
7 days after initial presentation, his clinical condition had improved together with a decrease in the parotid swelling and the size of the ulcer.
3/6
#MedTwitter #Doctor #MedStudentTwitter
3/6
#MedTwitter #Doctor #MedStudentTwitter
A 58-YO♂️, DM, fever & L lower quadrant abdominal pain 2 months prior: acute R-sided back pain, & 3/6 diastolic murmur at R upper sternal border.
CT: a R renal infarction & splenic embolism
MR: multiple infarctions
1/7
doi.org/10.1016/j.idcr…
#Cardiology #medicine #cardiologia
CT: a R renal infarction & splenic embolism
MR: multiple infarctions
1/7
doi.org/10.1016/j.idcr…
#Cardiology #medicine #cardiologia
Transesophageal echocardiography: a vegetation and severe aortic regurgitation.
Blood 🧫: Cardiobacterium hominis
CARDIOBACTERIUM HOMINIS ENDOCARDITIS ASSOCIATED WITH CEREBRAL, RENAL, AND SPLENIC INFARCTIONS
2/7
#IDtwitter #microbiology
Blood 🧫: Cardiobacterium hominis
CARDIOBACTERIUM HOMINIS ENDOCARDITIS ASSOCIATED WITH CEREBRAL, RENAL, AND SPLENIC INFARCTIONS
2/7
#IDtwitter #microbiology
The patient received antibiotic therapy and surgical aortic valve replacement, and he was doing well without major complications.
3/7
#infecciosas #MedTwitter #Doctor
3/7
#infecciosas #MedTwitter #Doctor
A 71-YO therapy for multiple mieloma, voriconazole for Aspergillus fumigatus sinusitis, prophylaxis with TMP-SMX: febrile neutropenia, nodular lesion on abdominal wall
CT: pulmonary nodule unchanged in last a month
🔬biopsy of pulmonary nodule?
1/8
#Pathologists #haematology
CT: pulmonary nodule unchanged in last a month
🔬biopsy of pulmonary nodule?
1/8
#Pathologists #haematology
🔬: Histiocytic process with granular basophilic cytoplasm and Michaelis-Gutmann bodies (arrows), positive for calcium with von Kossa special stain (arrowhead); findings pathognomonic for malakoplakia.
PULMONARY MALAKOPLAQUIA
2/8
doi.org/10.1093/cid/ci…
#pathTwitter
PULMONARY MALAKOPLAQUIA
2/8
doi.org/10.1093/cid/ci…
#pathTwitter
🧫of the pulmonary nodule:➖
🧫biopsy of the abdominal wall lesion: Rhodococcus equi resistant to TMP-SMX, but susceptible to rifampicin, vancomycin, azithromycin, ciprofloxacin, & imipenem.
RHODOCOCCUS EQUI SUBCUTANEOUS ABSCESS
3/8
doi.org/10.1093/cid/ci…
#microbiology
🧫biopsy of the abdominal wall lesion: Rhodococcus equi resistant to TMP-SMX, but susceptible to rifampicin, vancomycin, azithromycin, ciprofloxacin, & imipenem.
RHODOCOCCUS EQUI SUBCUTANEOUS ABSCESS
3/8
doi.org/10.1093/cid/ci…
#microbiology
A 57-YO Mexican♀️, works on a farm has several pets, including dogs, at home: epigastric fullness, and a 15-pound weight loss.
CT: complex cystic left liver mass.
1/5
doi.org/10.1093/cid/ci…
#gastroenterology #radiology #medicine
CT: complex cystic left liver mass.
1/5
doi.org/10.1093/cid/ci…
#gastroenterology #radiology #medicine
Resection: Cyst wall (red➡️), daughter cysts (*) normal liver tissue (yellow⬅️)
🔬acellular laminated wall (*), inner germinal layer (black⬅️), & protoscoleces surrounded by a broad capsule (green⬅️). Refractile hooklets (blue⬅️) & calcareous bodies (red⬅️)
2/5
#GIPath #IDtwitter
🔬acellular laminated wall (*), inner germinal layer (black⬅️), & protoscoleces surrounded by a broad capsule (green⬅️). Refractile hooklets (blue⬅️) & calcareous bodies (red⬅️)
2/5
#GIPath #IDtwitter
ECHINOCOCCAL CYST
The patient underwent total excision of the cyst followed by albendazole therapy for 4 weeks.
3/5
doi.org/10.1093/cid/ci…
#microbiology #GITwitter #MedStudentTwitter
The patient underwent total excision of the cyst followed by albendazole therapy for 4 weeks.
3/5
doi.org/10.1093/cid/ci…
#microbiology #GITwitter #MedStudentTwitter
A 50-YO ♀️ bitten by her pet rat: fever, myalgia, sore throat, headaches a nonpruritic rash on extremities including palms & soles, arthralgias, knees arthritis.
A punctate wound with central necrosis on L palm, & her R thumb.
1/9
#rheumatology #internalmedicine #dermatology
A punctate wound with central necrosis on L palm, & her R thumb.
1/9
#rheumatology #internalmedicine #dermatology
Leukocytosis with neutrophilia
ESR & PCR:⬆️
Purulent R knee synovial fluid:
✔️46 000 cells/mL (88% neutrophils).
✔️Gram stain: scant pleomorphic gram-negative bacilli in chains with lateral bulbar swellings
2/9
doi.org/10.1093/cid/ci…
#microbiology #rheumatologist
ESR & PCR:⬆️
Purulent R knee synovial fluid:
✔️46 000 cells/mL (88% neutrophils).
✔️Gram stain: scant pleomorphic gram-negative bacilli in chains with lateral bulbar swellings
2/9
doi.org/10.1093/cid/ci…
#microbiology #rheumatologist
Synovial fluid 🧫culture: Streptobacillus moniliformis identified by biochemical testing & confirmed by MALDI-TOF.
RAT BITE FEVER (RBF) WITH SEPTIC ARTHRITIS DUE STREPTOBACILLUS MONILIFORMIS
3/9
#bacteriology #IDtwitter #microbiología
RAT BITE FEVER (RBF) WITH SEPTIC ARTHRITIS DUE STREPTOBACILLUS MONILIFORMIS
3/9
#bacteriology #IDtwitter #microbiología
A 17-YO♀️, unprotected #sexual intercourse with multiple male partners: a 1-month history of pruritic genital lesions, multiple smooth, grayish-white papules & plaques were noted on the vulva & upper inner thighs.
1/5
DOI: 10.1056/NEJMicm2207538
#gynecology #womenshealth
1/5
DOI: 10.1056/NEJMicm2207538
#gynecology #womenshealth
A Treponema pallidum particle agglutination assay:➕
Rapid plasma reagin titer: ➕1:16.
CONDYLOMA LATA OF SECONDARY SYPHILIS
2/5
#microbiology #gynecologist #primarycare
Rapid plasma reagin titer: ➕1:16.
CONDYLOMA LATA OF SECONDARY SYPHILIS
2/5
#microbiology #gynecologist #primarycare
✔️Testing for other sexually transmitted infections, including HIV infection: ➖
✔️Counseling on the importance of condom use
✔️IM penicillin G benzathine
At the 1-month follow-up visit, the lesions had resolved, and the RPR was 1:8.
3/5
#dermtwitter #IDtwitter #MedTwitter
✔️Counseling on the importance of condom use
✔️IM penicillin G benzathine
At the 1-month follow-up visit, the lesions had resolved, and the RPR was 1:8.
3/5
#dermtwitter #IDtwitter #MedTwitter
A 29-YO♂️, 6 months before, HIV + & non–drug-resistant pulmonary tuberculosis, antiretroviral & 4-drug antituberculous therapy initiated but soon reduced to rifampin & isoniazid only: abdominal pain on the L side
CT: ?
1/5
DOI: 10.1056/NEJMicm2206174
#radiologist #GITwitter
CT: ?
1/5
DOI: 10.1056/NEJMicm2206174
#radiologist #GITwitter
CT: an enlarged spleen with numerous hypodense lesions (A).
CD4 cell count: 119/mm3
VIH viral load: 1778 copies/mm3
A splenectomy was performed to evaluate for cancer:
numerous necrotic nodules with purulent discharge (B).
2/5
#microbiology #gastroenterology #IDtwitter
CD4 cell count: 119/mm3
VIH viral load: 1778 copies/mm3
A splenectomy was performed to evaluate for cancer:
numerous necrotic nodules with purulent discharge (B).
2/5
#microbiology #gastroenterology #IDtwitter
🔬granulomatous inflammation with caseous necrosis (C) and acid-fast bacilli (D, arrowheads).
A tissue🧫: ➖
PCR: ➕for Mycobacterium tuberculosis
SPLENIC TUBERCULOSIS
3/5
#bacteriology #MedTwitter #GIPath
A tissue🧫: ➖
PCR: ➕for Mycobacterium tuberculosis
SPLENIC TUBERCULOSIS
3/5
#bacteriology #MedTwitter #GIPath
A 17-YO: a 3-week of dizziness, headache, & weakness of the R leg
MR: ring-enhancing lesions in the frontal lobe & basal ganglia on the L side (A; T1-W) as well as surrounding edema & midline shift (B; T2-W)
1/6
DOI: 10.1056/NEJMicm2202196
#neurology #radiology #IDTwitter
MR: ring-enhancing lesions in the frontal lobe & basal ganglia on the L side (A; T1-W) as well as surrounding edema & midline shift (B; T2-W)
1/6
DOI: 10.1056/NEJMicm2202196
#neurology #radiology #IDTwitter
IgG ab for Echinococcus multilocularis & E. granulosus: ➖
Surgical excision🔬: necrotic tissue, granulomatous inflammation, echinococcal laminated membrane (C, arrow) & an intact cyst (D, arrow)
RT-PCR: ➕for E. multilocularis
2/6
#parasitology #Pathologists #pathology
Surgical excision🔬: necrotic tissue, granulomatous inflammation, echinococcal laminated membrane (C, arrow) & an intact cyst (D, arrow)
RT-PCR: ➕for E. multilocularis
2/6
#parasitology #Pathologists #pathology
CT imaging of the chest and abdomen did not show any other sites of disease.
CEREBRAL ALVEOLAR ECHINOCOCCOSIS
3/6
DOI: 10.1056/NEJMicm2202196
#microbiology #MedTwitter #Doctor
CEREBRAL ALVEOLAR ECHINOCOCCOSIS
3/6
DOI: 10.1056/NEJMicm2202196
#microbiology #MedTwitter #Doctor
A 14-yo ♂️ lived on a farm: a 1-month history of episodic headaches, vomiting, & papilledema
MR: a multiloculated cyst of the brain (A) with a hypointense rim and small projections in T2 phase (B, arrow)
1/5
DOI: 10.1056/NEJMicm2208104
#neurology #radiology #pediatric
MR: a multiloculated cyst of the brain (A) with a hypointense rim and small projections in T2 phase (B, arrow)
1/5
DOI: 10.1056/NEJMicm2208104
#neurology #radiology #pediatric
Findings suggestive of CYSTIC ECHINOCOCCOSIS.
CT of the body: no other sites of disease.
A craniotomy was performed, during which saline irrigation was used to separate the cyst wall from the brain to avoid rupture.
2/5
DOI: 10.1056/NEJMicm2208104
#IDtwitter #parasitology
CT of the body: no other sites of disease.
A craniotomy was performed, during which saline irrigation was used to separate the cyst wall from the brain to avoid rupture.
2/5
DOI: 10.1056/NEJMicm2208104
#IDtwitter #parasitology
🔬: an echinococcal laminated membrane lined by a germinal layer with daughter cysts (Panel D, arrows) and protoscolices (inset, arrows) with hooklets (arrowhead).
PRIMARY CEREBRAL CYSTIC ECHINOCOCCOSIS FROM ECHINOCOCCUS GRANULOSUS
3/5
#microbiology #Pathologists #pathology
PRIMARY CEREBRAL CYSTIC ECHINOCOCCOSIS FROM ECHINOCOCCUS GRANULOSUS
3/5
#microbiology #Pathologists #pathology
A 50-YO♂️of North India, visited bat caves & a bird sanctuary in Thailand: multiple plaques & nodules on his face, neck, arms & trunk with hoarseness, fever, weight loss for months
Laryngoscopy: nodules over the tonsils & posterior pharyngeal wall
1/4
#medicine #dermatology
Laryngoscopy: nodules over the tonsils & posterior pharyngeal wall
1/4
#medicine #dermatology
Skin & laryngeal 🔬: histiocytes with intracellular & extracellular PAS+ yeast cells
Skin biopsy🧫: tuberculate macroconidia confirmed as H. capsulatum var. capsulatum
Ab against Histoplasma by ID:➕
DISSEMINATED HISTOPLASMOSIS
2/4
doi.org/10.3109/136937…
#mycology #IDtwitter
Skin biopsy🧫: tuberculate macroconidia confirmed as H. capsulatum var. capsulatum
Ab against Histoplasma by ID:➕
DISSEMINATED HISTOPLASMOSIS
2/4
doi.org/10.3109/136937…
#mycology #IDtwitter
Disseminated histoplasmosis involving skin & larynx in an apparently immunocompetent individual
The infection appeared to be imported from Thailand.
The patient responded very well to intravenous amphotericin B followed by itraconazole.
3/4
#microbiology #MedTwitter #Doctor
The infection appeared to be imported from Thailand.
The patient responded very well to intravenous amphotericin B followed by itraconazole.
3/4
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