Acute Pericarditis:
- Inflammation of the pericardium
- May be caused by number of factors: viral/bacterial infection, metastatic tumors, collagen vascular diseases, MI, cardiac surgery, and uremia
ECG Changes w/ Acute Pericarditis:
- Early phase is characterized by ST segment elevation, due to inflammation of the epicardium, which accompanies inflammation of the overlying pericardium
- Can have generalized ST-T changes in both anterior and inferior leads
ECG Changes w/ Acute Pericarditis:
- Also affects the repolarization of the atria (PR segment)
- Leads to atrial current of injury with elevation in PR segment in aVR and depression of PR segment in other extremity / left-sided chest leads
- Can have T-wave inversions
Pericardial Effusion:
- Abnormal accumulation of fluid in the pericardial sac, can be due to pericarditis
- Other causes: myxedema (hypothyroidism), or rupture of heart (VSD)
- Can lead to cardiac tamponade: drop in SBP leading to PEA activity
Pericardial Effusion ECG:
- Can see low QRS voltages (<5-mm in the 6 extremity leads or < 10-mm in the chest leads V1-V6)
- Low voltage: Obesity (fat around heart), emphysema (air insulates heart), anasarca (generalized edema), pleural effusions
- Electrical alternans
Chronic Constrictive Pericarditis:
- Some conditions cause pericardial inflammation and can lead to fibrosis and calcification of the pericardial sac (cardiac surgery, trauma, infections, TB, viral infections, connective tissue diseases, sarcoid, uremia, and asbestosis)
Chronic Constrictive Pericarditis:
- Can present with HF, elevated neck veins/ascites. Can be mistaken for liver cirrhosis.
- Treatment: Pericardiectomy ('surgical stripping' of the pericardium to decrease intra-cardiac pressures.
** Not to use for clinical care, just educational material**
Thanks to these websites/journals for amazing graphics!
Pre-Rounding Tips 3d: How to think about Troponin? (
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Pro-Tip: If you can print out a pre-rounding sheet with the labs auto-populated, that is always helpful.
One of the most common consults from the Emergency Room to Cardiology is 'elevated troponin.'
Yes, elevated troponin can be scary, but here is the framework that I use to analyze / consider troponin.
1. Patient Presentation? 2. Patient's risk factors and prior cardiac history? 3. What is the troponin trend? 4. What does the ECG look like? 5. What are some non-cardiac reasons troponin may be elevated?
1. Patient Presentation?
In Cardiology, the clinical presentation is the most important part of the story when determining the significance of an elevated troponin! In many situations, clinical decisions (whether to pursue a LHC) may be made in the absence of having a troponin available.
Key Questions: 1. If the patient presents with chest pain, how does he/she describe it?
- Some common worrisome symptoms associated with angina. Elevated troponin in the setting of these symptoms should always be taken seriously.
a) Chest pressure, constant, sub-sternal.
b) Radiation of pain to the neck or jaw
c) Diaphoresis
d) Numbness to the left arm
e) New onset dyspnea
f) Worse with exertion, better with rest
2. What makes the pain better?
- If the patient got improvement with nitroglycerin more likely to be consistent with cardiac chest pain.
- If patient's pain improves with muscle relaxers, IV toradol, IV PPI, IV Ativan, less likely to be a cardiac etiology.
3. Has the patient had this type of pain before?
- If similar recent presentation with a negative work-up, this might be reassuring. However, you don't want to have anchor bias and should keep an open perspective.
When I was an intern, pre-rounding was one of the most stressful parts of the day. I would take too long and be inefficient. Part 1.
Now as a PGY7 (long-time, right?), here is 3 parts of my system that I use for new patients.
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1) Why is the patient here / chief concern?
- This seems like the most basic question that is often overlooked. What made the patient decide to leave his/her house to come to the hospital?
- When reading the overnight H&P, the abundance of clinical documentation can create confusion.
- Simplicity is key. What is the chief concern? Is it chest pain? Is it dyspnea on exertion? Knowing this information will help frame your thoughts.
2) What are the relevant past medical problems?
- Most patients will have chronic medical problems that will contribute to the current presentation.
- It is easy to get lost in the weeds of this presentation. In Cardiology, I typically focus on (but not limited to) coronary artery disease, atrial fibrillation, hypertension, hyperlipidemia, diabetes mellitus, history of CVA. Again, this is not all inclusive but it is a start.
- Although patients may present to the hospital with a new diagnosis, it is more likely that the presentation may be an exacerbation of a previous problem.