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Tucker Goodrich Profile picture
@TuckerGoodrich
May 17 • 3 tweets • 2 min read Twitter logo Read on Twitter
1/2 So much for LDL.

"In our study, apoB48-containing intestinal particles occupied significantly larger area of human carotid atherosclerotic plaques, compared to hepatic apoB100."

@FatEmperor @realDaveFeldman @LDLSkeptic

#LDLBS #lcl6 Image
2/2 "First Quantification of Intestinal-apoB48 and Hepatic-apoB100 Particles in Human Atherosclerotic Plaque"

doi.org/10.1016/j.cca.…
Whoops, link to wrong place, here's the right one:

ahajournals.org/doi/abs/10.116…

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More from @TuckerGoodrich

Tucker Goodrich Profile picture
May 16
1/ A cardiologist will tell you:

A low-fat diet is healthy.

Lp(a) is a marker for CVD risk.

Lp(a) is genetic.
2/ "Thirty-seven healthy women were fed two diets. Both diets contained a reduced amount of total and saturated fat. In addition, one diet was low in vegetables and the other was high in vegetables, berries, and fruit. The dietary intake of total fat was...
3/ "...70 g per day at baseline and decreased to 56 g (low-fat, low-vegetable diet) and to 59 g (low-fat, high-vegetable diet). The saturated fat intake decreased from 28 g to 20 g and to 19 g, and the amount of polyunsaturated fat intake increased...
Read 6 tweets
Tucker Goodrich Profile picture
Apr 18
1/ A few thoughts on ApoB.

It's something we're programmed for, genetically.

It's a fundamental component of digestion and energy distribution. (@realDaveFeldman)

So if it causes CVD, then CVD is a genetic disease.

#lcl6 h/t @jimolsen717
2/ If CVD is genetic, then we should see the current rate of CVD (~50% of deaths) in all human populations.

We don't.

This is demonstrated repeatedly, best here:



Where various genetic populations have near-zero CVD in their natural environment.
3/ We only see CVD in populations consuming higher amounts of linoleic acid, and, best, low levels of animal fats.

doi.org/10.3389/fnut.2… Image
Read 13 tweets
Tucker Goodrich Profile picture
Feb 23
Does Ted Ryce Know the Truth About Seed Oils?

He asked folks to retweet this thread, so I'm going to, with some commentary.

tldr: No, he doesn't. Keep reading, Ted.
No, Ted, it's been going on for much longer than that. Paul Chek hardly started it.

"Before we jump in, I want you to know that this debate has been going on for over 20 years."

Here's a paper from 1961, proposing that seed oils (linoleic acid) are essential for atherosclerosis causation.

ncbi.nlm.nih.gov/pmc/articles/P…

That's 62 years ago.

Score: Ted = -1
Read 28 tweets
Tucker Goodrich Profile picture
Feb 22
#duh 1/ Dieticians are corrupt.

"@eatright and its foundation... received food industry fundings via sponsorships, which are in effect quid pro quos. In a 2015 email, an Academy employee defined a sponsorship as “When a company pays a fee to the Academy/Foundation in return...
2/ "...for Academy/Foundation defined specific rights and benefits.”

"The email reveals the Academy in 2015 was in a sponsorship deal with Abbott and was discussing how the Academy could use its dietitians’ influence in pediatricians’ offices to push Pediasure...
3/ "...one of the pharmaceutical giant’s infant nutritional products. Abbott at the time had in place a two year, $300,000 sponsorship deal.
Read 14 tweets
Tucker Goodrich Profile picture
Dec 26, 2022
1/15 Remember TMAO? #Vegan claim it comes from meat, and is bad for you, promoting heart disease.

"TMAO: A Toxic Substance Formed When You Eat Meat Can Make You … Dead Meat"
forksoverknives.com/wellness/tmao-…

Written by an MD!
2. Problem was, the most cardioprotective diet includes lots of fish, and fish are the best source for TMAO:

"Fish consumption yields a greater increase in urinary TMAO compared to red meat."

"The Relationship between Fish Intake and Urinary [TMAO]"
doi.org/10.1002/mnfr.2…
3. While a vegan diet does indeed decrease TMAO:

"Evaluation of an 8-Week #Vegan Diet on Plasma [TMAO] and Postchallenge Glucose in Adults with Dysglycemia or Obesity"

https:doi.org/10.1093/jn/nxa…
Read 15 tweets
Tucker Goodrich Profile picture
Nov 26, 2022
1/ "Conventional soybean oil (CSO)... predominantly contains linoleic acid (LA; C18:2), a n-6 PUFA. Recently, a modified soybean oil (MSO) enriched in oleic acid (C18:1), a n-9 MUFA, has been developed, because of its improved chemical stability to oxidation."

#lcl6
2/ "The CSO diet decreased plasma lipid levels and the cholesterol content of VLDL and LDL by approximately 18% (p < 0.05), likely from increased hepatic levels of PUFA, which favorably regulated genes involved in cholesterol metabolism...."

@FatEmperor @realDaveFeldman
3/ "The MSO diet, but not the CSO diet, suppressed atherosclerotic plaque size compared to the Western control diet (Control Western diet: 6.5 ± 0.9%; CSO diet: 6.4 ± 0.7%; MSO diet: 4.0 ± 0.5%) (p < 0.05), independent of plasma lipid level changes."

@LDLskeptic2
Read 4 tweets

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