"The study’s most significantly differentially expressed gene was NEAT1, which encodes a lncRNA in genomic proximity to MALAT1" > ncbi.nlm.nih.gov/pmc/articles/P…
MALAT1 and NEAT1 are dysregulated in COVID >
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Since we see a rise in lymphomas/aggressive lymphomas also after COVID💉,
what LncRNAs will be found dysregulated by the 💉 spike protein? >
2 interesting papers on blood signatures for
Sporadic CJD.
Researchers found 38 different DNA methylation sites related to sCJD.
9 of these sites were replicated in a further study, with sites in or close to genes: FKBP5, AIM2, UHRF1, KCNAB2 successfully replicated, specific to sCJD.
These were specific to sCJD vs other prion disease, or AD and found only in the blood, not brains of sCJD patients, suggesting a possible blood biomarker.
> tinyurl.com/bdnn7ysr
"Top 10 gene ontologies enriched in genes overlapping DMPs as identified using MetaCore (p value threshold = 0.1)." -Fig. 2
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"Loss of DNA methylation at 2 sites on the AIM2 promoter correlates with disease severity.
AIM2 is a key component of the inflammasome pathway...drives IL-1β"
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