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Janiesaysyay Profile picture
@janiesaysyay
May 31, 2023 • 10 tweets • 6 min read • Read on X
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MALAT1 & NEAT1

Long Non Coding RNAs, Lymphoma and COVID

Interesting paper on new potential biomarkers for aggressive lymphomas, LncRNAs.

It highlights the LncRNAs involved in lymphoma.

There are some similar LncRNAs dysregulated by COVID. > https://onlinelibrary.wiley...
> https://onlinelibrary.wiley...Image
> https://onlinelibrary.wiley...Image
MALAT1 and NEAT1 in Lymphoma > https://onlinelibrary.wiley...ImageImage
MALAT1 & NEAT1 in COVID

"The study’s most significantly differentially expressed gene was NEAT1, which encodes a lncRNA in genomic proximity to MALAT1" >
ncbi.nlm.nih.gov/pmc/articles/P…
MALAT1 and NEAT1 are dysregulated in COVID > Image
> Image
Since we see a rise in lymphomas/aggressive lymphomas also after COVID💉,
what LncRNAs will be found dysregulated by the 💉 spike protein? >

#LncRNA #miRNA #NonCodingRNA #MALAT1 #NEAT1 #Lymphoma #DiffuseLargeBcellLymphoma #BurkittsLymphoma #MantleCellLymphoma #cancer
#WhiteLines #HighAnxiety #LymPHAdeN0Pathy
nzherald.co.nz/sport/kiwi-woo…

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More from @janiesaysyay

Janiesaysyay Profile picture
Feb 24
🫁 Take My Breath Away 🫁

The SARS2 Spike Protein S1 Subunit,
Fibrosis & Risk of Lung Cancer 🧵

New research showing the S1 subunit of the SARS2 spike protein, when administered to 🐁
can cause severe tissue damage in the 🫁 > Image
Vascular permeability, compromised tight junctions, oxidative stress, lipid oxidation, and 📈 cytokines:
IL-6, IL-10, IL-1β, IL-17, TNF-α, IFN-γ, chemo MIG.

AND

"prominently augmented the expression of p-p65/P65 and attenuated IκBα expression in the NF-κB signaling pathway." > Image
(note the Spike RBD + LPS aggravated Acute Lung Injury)

This might also explain the sepsis seen in some C0VID
(🦠or💉) patients, like Shawn Kuhn. >
Image
Image
Read 20 tweets
Janiesaysyay Profile picture
Jan 29
Sweet n Low Caroline

Not content to push a myth about her scumbag father Jack who pimped his intern out for BJ's in the WH pool while he watched, and took her virginity on his marital bed, or her uncle Ted who drove drunk into Chappaquiddick, then nursed his hangover as > Image
Mary Jo Kopechne suffocated in his car, or her cousin David who OD'd on coke alone in a hotel room, or her cousin Joseph who drove recklessly, paralyzing 18 yr old Pamela Burkely; or her cousin Michael who beat and st@bbed his 15 yr old neighbor Martha Moxley to 💀 >
or her cousin Michael who brutally r@ped a woman he'd just met while drunken Uncle Teddy swaggered around pantless and singing; or her cousin Michael who repeatedly r@ped his 14 year old nanny then 💀 after drunkenly skiing into a tree, or her cousin Patrick who drove drunk >
Read 8 tweets
Janiesaysyay Profile picture
Jan 21
➰ Torn ➰

The C0VID 💉 uses lipid nanoparticles as a
protective shell for delivery of the mRN🅰️ into the cell.

👨‍🔬👩‍🔬 used precise cryo-TEM imaging to understand
how LNPs can cause irreversible damage to cell
membranes as they cross them. > Image
After introduction to the cell membrane, the LNPs
cluster around it, and because of adhesive attractions
between them, the LNPs can become attached,
wrapped and enwreathed by the cell membrane.

This allows translocation of the LNPs across the membrane & delivery of the mRN🅰️. > Image
This process achieves the delivery of the payload but, ultimately at the expense of the membrane.

During the process, tears can occur which are permanent and, in time, can destroy the cell membrane completely.

The initial adhesion happens quickly, < 20 seconds.
> Image
Image
Read 18 tweets
Janiesaysyay Profile picture
Dec 4, 2024
🪨 Turn to Stone 🪨

A journey of discovery.

2 years ago Richard Hirschman bravely put his images on social media and it started me thinking about mechanisms which could cause such tough rubbery clots. >

🧵🧵s
keep showing replies
Where they in the bodies of unvaxxed with C0VID,
or 💉 or both?

Unclear.

What became clear is, that there are mechanisms for persistent clots in the bodies of both.
#MicroClots #TeamClots #TinyBubbles #LetItAllHangOut #DiamondsOnTheSoleOfHerShoes>
Both the 🦠 and the 💉 produce the spike protein bi0weapon in the cells.

The spike can form #MicroClots
#ICanDoBadAllByMyself

The vaxxed seem to have more elements for forming the tough rubbery #CalamariClots >
Read 5 tweets
Janiesaysyay Profile picture
Oct 26, 2024
💪 Muscles 💪

Scientists found an unusual metabolic disruption in
the skeletal muscles of prion infected 🐭 & 👨

This may be a new predictive marker for prion disease. > https://tinyurl.com/358pk6hk
They also found genetic changes in the spleens and blood, with muscle showing the most consistent changes.

Alteration of the Glutamate Ammonia Ligase Gene (GLUL) led to reduced glutamate levels in skeletal muscles. > Image
The observed changes were unique to prion diseases. > Image
Read 9 tweets
Janiesaysyay Profile picture
Oct 23, 2024
🌊 WIPEOUT 🌊

What happens when a lab created chimeric 🦠 with gene inserts of HIV, is used as a template for a gene therapy, which also includes an HIV fragment as a stabilizing agent? > Image
🧵 keep showing replies >
"Their bifidobacteria dropped from like a million to zero"

Dr. Hazan found that the SARS2 spike protein (🦠&💉) had the ability to ##WIPEOUT the good gut bacteria.

This bacteria is the guardian of our immune system. >
Read 7 tweets

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