3. If I cared to own the future, as leader, I would simply not infect all my children with a virus that has sequence similarity with HIV-1 gp120, dog rabies virus and snake neurotoxins. Not to mention all the SARS-CoV-2 proteins not included in this study. jbc.org/article/S0021-…
4. All this was known since at least September 2020. Some references:
5. I summarize because the great problem in society is that knowledge isn't translated into forms that can be understood by average policymakers and the public. Knowledge is siloed.
@ArditiMd 6. Mutations in one or more SARS-CoV-2 proteins that make Omicron more severe for children can occur at any moment. Here S:K97E in Taiwan in BA.2.3, just as Taiwan gave up on #ZeroCovid policy in April 2022.
1. To add to @RealCheckMarker’s humor: I too am honored to see @TheVertlartnic grace my sarcastic scicomm tweet with a pithy headline. It is a shoutout to the epidemiologists, WHO and leaders who eradicated SARS-CoV-1 in 2003. No small feat as we now know.
2. This is funny because the middle is a screenshot from a locked account, shared here to explain the context of my original post. Otherwise it hangs a bit in the void.
SARS-CoV-1 and -2 are nearly the same (SARS) virus. We could have saved years by admitting it from the start.
3. It is not new. I’ve been cracking this joke since January 2020. If you see its long beard, you may think, “probably the lockdowns”.
1. I discussed climate-AI interactions since 2017, so I appreciate @_david_ho_ being honest. (1) AI will significantly increase energy use and greenhouse gas emissions. (2) We will need capable AI to replace and help all the people with SARS-CoV associated neurocognitive decline.
2. Heads up to variant chasers, here interesting abstracts on SARS-CoV-2 mutation N:R203M, which increases viral load, and on Alzheimer’s disease. Good editorial work if that’s a conscious placement. Good luck everyone, reach out if you want solutions. 👍 ncbi.nlm.nih.gov/pmc/articles/P…
2. It's a joke👆and interesting science. @nephologue cautions that coarse-grid climate models are no reliable tools for feedbacks. They may overestimate the role of both aerosols and policy interventions. Greenhouse gases, not aerosols, as the key drivers.
2. Our friends in Hollywood work hard to model the real world for us through popular culture. Winning by attrition describes sarbecovirus and human monkeypox virus (hMPXV) policy quite well, whether you think of either virus as pandemic or newly ‘endemic.’
3. These very human dynamics are fascinating to systems thinkers. Two viruses - the poxvirus in its evolutionary infancy, not yet efficiently airborne, the coronavirus evolving fast already - are starting to downregulate the exuberant expression of humanity on this lovely planet.
Shell execs can smirk and say “we keep civilization running”, and they would be right. Yet running civilization into climate hell is a low-creativity low-value add use of your time and talent, wouldn’t you say?
2. The system can currently only keep up appearances by going ever deeper into denial. That’s good for pathologically shortsighted people without conscience and bad for almost all humanity long term.
1. To address disinformation, do the truth-sandwich. Analysis of 81 million health records shows SARS-CoV-2 infection increases epilepsy and seizure. It's not the vaccine—which helped PREVENT this. 👇 Recall the video footage from Wuhan 2020? #diedsuddenlyn.neurology.org/content/100/8/…
Red queen theory refers to evolution and system dynamics, illustrated by @ricard_sole. Unglycosylated variants in Wuhan like Orf8:N78Q (would have) caused cytokine storm and seizure.
Orf8:N78 glycosylation blocks interaction with IL-17RA.