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Vincent Rajkumar Profile picture
@VincentRK
Jun 2 • 6 tweets • 5 min read Twitter logo Read on Twitter
mSMART guidelines for management of CAR-T associated cytokine release syndrome, neurotoxicity, cytopenias has just been posted. #myeloma #MedTwitter

@YiLinMDPhD @myelomaMD @MorieGertz @MayoMyeloma

msmart.org
CAR-T associated CRS #ASCO23 Image
CAR-T associated neurotoxicity #ASCO23 Image
CAR-T associated late neurotoxicity #ASCO23 Image
Post CAR-T cytopenias Image
Thanks to @YiLinMDPhD for spearheading our CAR-T and immunotherapy program @MayoClinic @MayoCancerCare and leading the development of these guidelines.

@Rfonsi1 @MorieGertz @myelomaMD

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More from @VincentRK

Vincent Rajkumar Profile picture
Apr 2
Thanks to the Inflation Reduction Act, 2 big changes coming up for Medicare Part D beneficiaries. #MedTwitter

1) Starting 2024, once you pay ~$3250 out of pocket, you won’t have any more copays. The 5% copay you currently pay will go away. This is HUGE.
#MedTwitter
2) Starting 2025, your annual copay max will be capped at $2000 for Medicare Part D.

Once you spend that much out of pocket, you won’t have any more copays for Part D prescription drugs.
Patients with cancer spend huge amounts in copays currently. The drug Revlimid I prescribe costs $17,000 for 21 day supply.

5% of $17,000 every month is a massive amount of money for most.
Read 5 tweets
Vincent Rajkumar Profile picture
Mar 25
Three concerns I heard from patients at a recent meeting.

#MedTwitter
1/
First, as many complex treatments move from hospital to outpatient setting, patients are being saddled with high bills for parking, food, & lodging.

This is on top of all the usual copays. It widens disparities. Those who can’t afford to pay, don’t get the care they need.
2/
Second, prior authorization is wearing down patients already weary from the illness they have.

Patients have to fight and spend hours with insurance companies to get the tests and treatments their own physicians prescribed for them.

3/
Read 4 tweets
Vincent Rajkumar Profile picture
Mar 17
Breaking: @SanofiUS will cut list price of best selling Lantus insulin by 78%.

Yes! This follows similar announcements by @LillyPad and @novonordiskus
#insulin4all

I hoped this will happen and it has. This will help millions in America. @ZacharyBrennan endpts.com/threes-company…
List price reduction for Lantus starts Jan 2024.

Lillypad announced that it is launching a Lantus equivalent biosimilar at 78% discount to Lantus starting April 1, 2023. And it’s also interchangeable with Lantus.
Sanofi has already a Lantus authorized generic at 70% discount to Lantus launched last year. Let the price drops due to competition begin! It’s good for patients.

Read Sanofi press release: @sanofi sanofi.com/en/media-room/…
Read 7 tweets
Vincent Rajkumar Profile picture
Mar 14
As I had hoped, it has happened. Following @LillyPad decision to cut insulin prices, @novonordiskus follows suit.

Advocacy works. Public pressure works. @Loftus reports. wsj.com/articles/insul…
Insulin manufacturers voluntarily slashing list prices of insulin is monumental— a result of advocacy by patients, advocates like @NSmithholt12 & leaders like @SenSanders

@novonordiskus will cut list price of NovoLog by 75% and Levemir by 65%. Starts January 2024.
Next up, I hope @SanofiUS will follow suit. They make the best seller Lantus.

We also need policy changes at federal level to make this relief enduring and to make sure manufacturers don’t hike prices again. To help all other prescription drugs.
Read 6 tweets
Vincent Rajkumar Profile picture
Mar 11
Pay or Die.
Premieres today @sxsw

@PayorDieFilm
The high cost of Insulin in America. #Insulin4all
@scottaruderman @SarahKSilverman @NSmithholt12
The story behind @PayorDieFilm

payordiefilm.com/directors-stat…
The film is powerful.
Read 6 tweets
Vincent Rajkumar Profile picture
Mar 9
Paradigm Changes in Myeloma.
#MedTwitter

1. End organ damage is no longer needed to diagnose myeloma.
@TheLancetOncol linkinghub.elsevier.com/retrieve/pii/S…
2/ Smoldering myeloma (SMM) is no longer considered an intermediate biological state between MGUS and myeloma.

It’s heterogenous. 2/3 of patients with SMM have MGUS. 1/3 have myeloma. @BloodCancerJnl @SagarLonialMD @mvmateos @myelomaMD nature.com/articles/s4140…
3/ Screening for myeloma should be considered in ultra high risk groups. @Nature nature.com/articles/d4158…
Read 11 tweets

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