Daniel Gewolb, MD Profile picture
Jun 8, 2023 9 tweets 6 min read Read on X
What is the most likely diagnosis in this 30 y/o w/ history of discitis/osteomyelitis presenting w/ fevers, chills, and neck pain? 🧠
#ent #Neurosurgery #Neurology #medtwitter #MedEd @The_ASSR #NeuroTwitter ImageImageImageImage
Answer: Longus Colli Calcific Tendinitis

▶️Etiology: inflammatory reaction in response to deposition of calcium hydroxyapatite crystals (just like in the rotator cuff)

▶️This case is a bit tricky as the history is somewhat misleading (though it often is in radiology)
Imaging:

▶️Sagittal STIR shows marked retropharyngeal/prevertebral edema (yellow arrow) and focal hypointensity from the hydroxyapatite crystals (green arrow)

▶️Axial T2 again shows the marked edema ImageImage
▶️T2* is key in this case showing the markedly hypointense amorphous calcs at the longus colli tendons

▶️Pre and post con T1 shows the edema w/ reactive enhancement (yellow arrows) and the focal hypointense calcs (green arrows) ImageImage
General imaging features:
▶️Amorphous calcifications at C1-C2 junction near the insertion of the longus colli muscles is pathognomonic

▶️ Be careful not to mix up calcification at the C1-C2 junction w/ the more common COARSE calcs in DJD!
Imaging cont:

▶️Calcs on MR can be trickier, look for MARKED FOCAL HYPOINTENSITY on T2*/GRE at the C1-C2 JUNCTION

▶️Expect prevertebral and/or retropharyngeal edema

▶️Reactive soft tissue enhancement on T1C+
DDX:
Must differentiate from infection (as calcific tendinitis is treated with time and NSAIDs)

▶️For infection, expect a more spherical or convex retropharyngeal collection, more enhancement, and presence of head and neck infection
▶️Calcifications at the C1-C2 junction are pathognomonic for calcific longus colli tendonitis 🧠

Companion cases:
▶️Radiograph showing prevertebral swelling and amorphous calcs on C1-C2 junction
▶️Appearance on CT in a different patient showing the amorphous calcs and edema ImageImageImage
Companion case 3 (DJD fake out!!):

▶️CT shows COARSE calcifications at C1-C2 junction with mild pharyngeal edema (from prior radiation in this case) ImageImage

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More from @daniel_gewolb

May 8
Distinguishing between pathologic & compression fractures can be difficult

Here are some tips to help in 🧵

#Neurosurgery #MedEd #medicine #neurology #radres #futureradres


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🔷Some findings more suggestive of pathologic fracture:

1️⃣Other spinal mets Image
2️⃣Epidural mass, especially when encasing the cord

3️⃣Focal paraspinal mass (beware, sometimes hematoma in compression fracture can mimic paraspinal mass)
Read 8 tweets
Mar 23
Neuroimaging checklist for the patient with Temporal Lobe Epilepsy (TLE) 🧠 ✅

Credit to the excellent talk on the @TheASNR fellowship curriculum given by @EMiddlebrooksMD for inspiration on this topic

#MedEd #medicine #radres #Neurology #Neurosurgery #futureradres


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1.Encephalomalacia (usually from old infarct, trauma, etc.)
2.Mesial Temporal Sclerosis
3.Sphenoid encephaloceles
4.Prominent arachnoid pits (may be encephalocele precursors)
5.Temporal lobe epilepsy with Amygdala enlargement
6.Focal Cortical Dysplasia
7.Polymicrogyria
8.Gray matter heterotopia
9.Tumors
10.HSV encephalitis
11.Autoimmune encephalitis
12.Hypothalamic hamartoma
13.Other infections (NCC, TB, etc.)
14.Incomplete hippocampal inversion (uncertain significance)
15.Others, please add 🙏
Read 20 tweets
Feb 2
What is the most likely diagnosis in this 70 y/o w/ history of pontine infarct ~8 months ago now presenting with worsening ataxia and dysmetria?

#MedEd #radres #Neurology #neurosurgery #futureradres #Radiology


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Answer (probable): Wallerian degeneration of the pontocerebellar fibers

🔷I only have 1 time point w/o follow up nor images of the pontine infarct. This patient also had cirrhosis. It is possible that the tracts have degenerated due to hepatic encephalopathy or other process
🔷Regardless of the cause in this case, it is important to be aware of these fiber tracts and their appearance when degenerated. Additionally, many other diagnoses can look similar and involve the bilateral middle cerebellar peduncles w/ differential in 🧵
Read 14 tweets
Jan 12
What is the most likely diagnosis in this 75 y/o M w/ history of Alzheimer’s disease on lecanemab (last infusion ~1 week prior) presenting w/ headache and confusion? 🧠

More images in 🧵

#MedEd #Neurology #medicine #radres #Neurosurgery #futureradres @a_charidimou


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More images 👇

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Answer: Amyloid-related imaging abnormalities (ARIA)

🔷ARIA is a term used to describe a spectrum of imaging findings in patients receiving anti-amyloid beta immunotherapies for Alzheimer’s disease

💡 Tips and learning points for this complex topic are welcome as always 🙏
Read 15 tweets
Jan 7
Imaging Quick Tips & Tricks for Cranial Neuropathies 🧠

A neuroimaging 🧵 on check areas and pathology

#neurology #meded #medicine #neurosurgery #ent #radres #futureradres @AlbanyMedRadRes @PennRadiology


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💡 General imaging tips:

1️⃣Big issues and certain cranial nerves see on routine MR
2️⃣Thin slice high res axial and coronal T2 sequences (FIESTA, CISS, SPACE, etc.) useful for cisternal segments
3️⃣T1C- and T1C+ w/ fat sat best for extracranial segments
4️⃣CT often complementary
🔷OLFACTORY NERVE (CN 1)

📺 Imaging:
▶️Not well seen on routine brain MRI
▶️Seen well on coronal T2 MR
▶️Include medial temporal lobes in assessment
▶️Nasal vault and cribriform plate seen well on coronal CT of sinuses or orbits
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Read 36 tweets
Dec 23, 2023
What is the most likely diagnosis in this 25 y/o M presenting with right facial paralysis and pulsatile tinnitus?

More images in 🧵

#ENT #MedEd #Neurology #Neurosurgery #radres #futureradres @ASHNRSociety


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More images 👇


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Answer: Temporal Bone facial nerve venous malformation (Hemangioma)

🔷These are benign congenital venous malformations
Read 13 tweets

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