DDX:
Must differentiate from infection (as calcific tendinitis is treated with time and NSAIDs)
▶️For infection, expect a more spherical or convex retropharyngeal collection, more enhancement, and presence of head and neck infection
▶️Calcifications at the C1-C2 junction are pathognomonic for calcific longus colli tendonitis 🧠
Companion cases:
▶️Radiograph showing prevertebral swelling and amorphous calcs on C1-C2 junction
▶️Appearance on CT in a different patient showing the amorphous calcs and edema
Companion case 3 (DJD fake out!!):
▶️CT shows COARSE calcifications at C1-C2 junction with mild pharyngeal edema (from prior radiation in this case)
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Answer (probable): Wallerian degeneration of the pontocerebellar fibers
🔷I only have 1 time point w/o follow up nor images of the pontine infarct. This patient also had cirrhosis. It is possible that the tracts have degenerated due to hepatic encephalopathy or other process
🔷Regardless of the cause in this case, it is important to be aware of these fiber tracts and their appearance when degenerated. Additionally, many other diagnoses can look similar and involve the bilateral middle cerebellar peduncles w/ differential in 🧵
What is the most likely diagnosis in this 75 y/o M w/ history of Alzheimer’s disease on lecanemab (last infusion ~1 week prior) presenting w/ headache and confusion? 🧠
1️⃣Big issues and certain cranial nerves see on routine MR
2️⃣Thin slice high res axial and coronal T2 sequences (FIESTA, CISS, SPACE, etc.) useful for cisternal segments
3️⃣T1C- and T1C+ w/ fat sat best for extracranial segments
4️⃣CT often complementary
🔷OLFACTORY NERVE (CN 1)
📺 Imaging:
▶️Not well seen on routine brain MRI
▶️Seen well on coronal T2 MR
▶️Include medial temporal lobes in assessment
▶️Nasal vault and cribriform plate seen well on coronal CT of sinuses or orbits