Alfonso Martinez Arias Profile picture
Born and bred in Madrid, brewed in Chicago and Cambridge. Curious about how cells build embryos #NotIntheGenes #InNumbersWeTrust
Jul 2, 2023 24 tweets 5 min read
There seems to be some scrambling of my thread#2 so, I am repeating it here for clarity 1/n Thread#2
The ms , a #preprint, is a piece of cellular tinkering. The structures are remarkable and reflect not only the cell types of the conglomerate YS/EPI but also their organization. it shows that the TB is dispensable for the bilayered organization.biorxiv.org/content/10.110…
Jul 2, 2023 35 tweets 7 min read
Thread#2
The ms , a #preprint, is a piece of cellular tinkering. The structures are remarkable and reflect not only the cell types of the conglomerate YS/EPI but also their organization. it shows that the TB is dispensable for the bilayered organization.biorxiv.org/content/10.110… IMO, this is, probably, the best model of the four that contain two elements. The cells proliferate and organize themselves properly. It contains insights into the signalling inputs and provides insights into the role of the #Primitive Endoderm on the patterning of the EPI.
Jun 21, 2023 10 tweets 2 min read
Something strange is happening in certain realms of biology. Let me tell you a story A scientist (let’s call them scientist nr 1) and a journalist make the announcement, in the form of an exclusive, of an important discovery that triggers a wave of headlines around the world.
Jun 19, 2023 14 tweets 5 min read
Many of the arguments shorturl.at/kDNX5 are correct but @guardian should be careful not to exaggerate statements of scientists & misinform the public. #Thread In particular it is questionable whether scientific data that are not publicly available and thus not verifiable should be communicated in newspaper and used to make moral and ethical judgements.
Dec 30, 2022 8 tweets 3 min read
It is difficult to understand why @Nature publishes papers like this nature.com/articles/s4158… whose title promises much but which in the end is, simply, a data set with little insight & a number of misleading statements. Perhaps the most valuable figures, which are not discussed in sufficient detail, are 2d and 4b where there we can see some spatial expression. Rather than genes that are the same, it would have been good to see differences.
Mar 17, 2020 16 tweets 6 min read
#BSDBGenSoc2020 final part The results show that gastruloids are organized and that this organization corresponds to that of the embryo; see go.nature.com/3d0lB6b for details.
Mar 17, 2020 25 tweets 13 min read
#BSDBGenSoc2020 These days we all have other things in our minds, it is difficult to concentrate and many of my thoughts R w/ family anf friends in #Spain) but discussing our work, is an important part of our being and it is going to be important in the weeks and months to come. While many, all, of us rather do al this in person, we are going to have to adjust in the weeks to come. #BSDBGenSoc2020 is a good way to explore how we are going to do it so, THANKS @_BSDB_ and @the_Node for organizing and running this.