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Al-Ola A Abdallah MD (USMIRC) Profile picture
Al-Ola A Abdallah MD (USMIRC)
@Abdallah81MD
Associate Professor,Plasma Cell disorder program Director, Division of HMCT/University of Kansas Medical Center, no COI, #USMIRC Founder, #mmsm @KUMedCenter
Feb 1 • 4 tweets • 1 min read
1/Treatment of Myeloma:
- Transplant Eligible: (HR/SR)Dara/RVd
- Ineligible SR (DRd preferred)
Ineligible HR (VRd)
- Maintenance SR: lenalidomide
- Maintenance HR: VR (less evidence)
- 1st Relapse (HR/SR)Dara based therapy
- post triple RRMM: CAR-T then BCMA TCE then GPRC5D
#mmsm #myeloma #MedTwitter #MedEd #USMIRC @USMIRCNEWS @OncoAlert 2/Although 1q is considered as a High risk I still treat it as standard risk till I see more studies to show the impact of treatment on the outcomes!
- Regarding EMD (soft tissue) they are considered HR and treated within that group #mmsm #myeloma #MedTwitter #MedEd #USMIRC @USMIRCNEWS @OncoAlert
Jun 24, 2023 • 6 tweets • 5 min read
Hematology and Medical Oncology conference/ Kansas: Updates from ASCO 2023 #mmsm #myeloma #MedTwitter #MedEd #USMIRC Relapse myeloma still a challenge! 3 classes (IMiDs, PI and CD38 MoA) played a role to improve survival & we are looking to see BCMA Directed therapy added





BCMA CAR-T based on 2 RCT showed improved PFS compared to SOC and that is enough for me to change SOC to either Ide-Cel/Cilta-Cel #mmsm #myeloma #MedTwitter #MedEd #USMIRC





Jun 17, 2023 • 7 tweets • 11 min read
Flame Cells: These are plasma cells with vermillion-staining glycogen-rich overstuffed fibrils. Although these cytoplasmic features are suggestive of neoplastic plasma cells, can also be found in reactive cells. imagebank.hematology.org/image/3230/fla… #mmsm #myeloma #MedTwitter #USMIRC #MedEd ImageImage Mott cell is a plasma cell characterized by an accumulation of multiple Russell bodies, globular cytoplasmic inclusions composed of immunoglobulin imagebank.hematology.org/image/61837/mo… #mmsm #myeloma #MedTwitter #MedEd #USMIRC ImageImage