How do metastatic #ovariancancer tumors change during #chemotherapy to survive, eventually killing the patient? See our longitudinal #scRNAseq analysis, now out @ScienceAdvances, with accessible data & tools.
science.org/doi/10.1126/sc…
A 🧵 below (1/9) We collected a unique set of paired, metastatic tumor specimens from 11 high-grade serous patients treated in @TyksVsshp (by @mijohy & colleagues) before and after neo-adjuvant chemotherapy, and analysed dissociated tumors with scRNA-seq. (2/9)