Dagmar Iber Profile picture
President of the ETH University Assembly & Professor for Computational Biology: data-driven modeling & simulation of emerging phenomena in development & disease
Mar 4, 2022 10 tweets 8 min read
How precise are noisy #morphogen gradients in #tissue #patterning?

It turns out that the positional information they convey to #cells in the #neuraltube is much more accurate than previously estimated!

Our new #devbio paper is out in @NatureComms: rdcu.be/cH8Fx Image A methodological subtlety has previously led to overestimated positional errors of the morphogen gradients in the mouse neural tube. We reanalysed the noisy gradients and found that the positional information they can convey to cells is actually orders of magnitude more precise. Image