COVID-19: post infection implications in different age groups, mechanism, diagnosis, effective prevention, treatment, and recommendations

Again, Interesting review article, but now with an in-depth and detailed point analysis, worth your time and this 🧵👇

“This review offers a comprehensive understanding of the persistent effects of COVID-19 on individuals of varying ages, along with insights into diagnosis, treatment, vaccination, and future preventative measures against the spread of SARSCoV-2”

Highlights
• COVID-19 induces long-term effects in individuals of both genders of various ages.
• Artificial intelligence-based COVID-19 diagnostic tools are efficient.
• Pharmacological and non-pharmacological treatments reduced the long-term impacts of
COVID-19.
• All vaccines significantly reduced the persistent effects of COVID-19.
• No vaccine provides lifetime protection against COVID-19.
• Protective measures greatly limit SARS-CoV-2 transmission 1/n Sarscov2 introduction 2/n

❗️Excellent new CardioVascular Autonomic dysfunction(CVAD) overview:
For one: "As well as global circulatory disturbances, CVAD in post-COVID-19 syndrome(LongCovid) can manifest as microvascular and endothelial dysfunction, with local symptoms such as headache, brain fog, chest pain, dyspnoea and peripheral circulatory symptoms, including skin discolouration, oedema, Raynaud-like phenomena, and heat and cold intolerance"
➡️ Your N. Vagus at work!😰
nature.com/articles/s4156…
➡️ "CVAD arises from a malfunction of the autonomic control of the circulation, and can involve failure or inadequate or excessive activation of the sympathetic and parasympathetic components of the autonomic nervous system" 2/n

SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)

Lets revisit this excellent study, with a breakdown today on how the different pathways 🧵

➡️“This reservoir could modulate host immune responses or release viral proteins into the circulation”

illustrating the possible huge impact from different angles on your immune system, while SarsCoV2 defend a prolonged occupancy of your body! 1/n 2/n

SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)

Lets dig into 1 of the 8 mechanisms that could cause LongCovid in this excellent study illustrating the importance of possible vagus involvement:

“SARS-CoV-2 reservoir may alter vagus nerve signaling”

🧵1/n
“A SARS-CoV-2 reservoir could also contribute to nonspecific PASC symptoms including fatigue, trouble concentrating, muscle and joint pain, sleep dysfunction, anxiety, depression, loss of appetite and autonomic dysfunction. These symptoms overlap with the sickness response (called ‘sickness behavior’ in animal models) that reflects the subjective and behavioral component of innate immunity and is largely mediated by signaling of the vagus nerve” 2/n

Why so little attention in #Belgium(=new red zone) for our well performing neighbor, Germany(Green zone)? They certainly seem to have their act together, surely they could be instrumental to learn from! #Thread #covid19 1/n
@alexanderdecroo @JanJambon @eliodirupo Testen:
FREE testing everywhere, with results in 15 minutes , to be stopped Oct 11, to further push unvaccinated to get their shot.
Mandatory tests in schools(2-3x/w) and all employers have to provide them for the employees at work. 2/n