Isabella Cooper Profile picture
PhD researcher in Ketogenic Science and Hyperinsulinemia. AMRSB. Biochemistry/Physiology/Pathology/Ageing.
The Real Dr. Steven Horvitz Profile picture Paul Melzer Profile picture Kim Profile picture Whathefunk Profile picture 5 subscribed
Sep 23, 2022 9 tweets 1 min read
Keto-flu is a misnomer.

The symptoms one experiences when removing carbohydrates from one’s diet is actually the body experiencing chronic carbohydrate overdose addiction withdrawal symptoms.

Aka carb dependency withdrawal Carbohydrate withdrawal symptoms is not implying the symptoms are only because of addiction.
Dec 3, 2021 10 tweets 2 min read
Why did so many German doctors join the Nazi Party early?

“During the Weimar Republic in the mid-twentieth century, more than half of all German physicians became early joiners of the Nazi Party, surpassing the party enrollments of all other professions”

sciencedirect.com/science/articl… “From early on, the German Medical Society played the most instrumental role in the Nazi medical program, beginning with the marginalization of Jewish physicians, proceeding to coerced “experimentation,” “euthanization,” and sterilization, and culminating in genocide via…
Sep 6, 2021 7 tweets 3 min read
Patients with T2DM, CVD, conditions of hyperinsulinaemia, have lower: bone remodelling and osteocalcin levels, and increased rates of fragility fractures.

T2DM “hyperinsulinaemia-osteofragilitas” bone phenotype presents with normal to increased BMD mdpi.com/2227-9059/9/9/… Hyperinsulinaemia and IR positively associate with increased BMD and fragility fractures

Hyperinsulinaemia enforces glucose fuelling, decreasing NAD+-dependent antioxidant activity:

➡️⬆️ ROS & mt fission,
➡️⬇️ OxPhos ATP production capacity, needed for osteoblasto/cytogenesis.
Aug 15, 2021 4 tweets 1 min read
cancerres.aacrjournals.org/content/49/14/…

Can you believe, this was published in 1989.

Mice were given a ketosis inducing high fat diet (using MCT oil as 80% of calories), this reduced tumour mass whilst maintaining body weight, reducing cachexia, which is the most dangerous phase of cancer. The problem in dietary interventions in mice studies, is a lack of clarity in an accurate description of the diet and its subsequent metabolic/endocrine effects. Many research papers, when calling an intervention a high fat diet, they actually mean high carb with high fat...
Jun 26, 2021 8 tweets 2 min read
Trends in Prevalence of Diabetes Among US Adults, 1999-2018

Cross-sectional study
n=28,143 participants from NHANES

Estimated age-standardized prevalence of diabetes increased significantly, from 9.8% in 1999-2000 to 14.3% in 2017-2018 jamanetwork.com/journals/jama/… This is data where diabetes is overt. There are stages of T2 diabetes:

stage 1: hyperinsulinemia with normal glucose levels,

stage 2: hyperinsulinaemia with mildly elevated glucose levels (aka pre-diabetes),

stage 3: hyperinsulinemia with hyperglycaemia (full blown T2DM),…
Jun 12, 2021 39 tweets 11 min read
Risk of exposure to babies being fed by mothers vaccinated with SARS-CoV-2 experimental vaccine-mRNA

There can be no assurances of safety, with so many unknowns

hartgroup.org/risk-to-babies… It is being claimed that:

1.Human breast milk does not contain SARS-CoV-2 vaccine-mRNA; and

2.That if there were any vaccine-mRNA in breast milk, it would not survive the nursing infant’s digestive tract.

facebook.com/10001433352474…
May 2, 2021 26 tweets 5 min read
Why spike protein containing or mRNA transcription to self-produce the spike protein (S-protein) is likely to increase blood clotting and inflammation, especially in at-risk individuals:
The SARS-CoV2 (SARS2) spike protein is biologically active.

ahajournals.org/doi/full/10.11… The injected S protein (or program via mRNA to induce self-production of the S protein) alone damages vascular endothelial cells (ECs) in vitro and in vivo, manifested by impaired mitochondrial function, decreased ACE2 expression and eNOS activity, and increased glycolysis.
Jan 31, 2021 22 tweets 6 min read
The world’s most powerful tools against respiratory infections is good health, individual health and population health. Both metabolic and mental.

dx.doi.org/10.1136/openhr…

#hyperinsulinaemia
#covid
#vitD
#metabolichealth
#immunity openheart.bmj.com/content/7/2/e0… “heightened fears that the coronavirus is quickly finding ways to elude the world’s most powerful tools (vaccines) to contain it.”

latimes.com/science/story/…
Jan 30, 2021 14 tweets 2 min read
An uncomfortable topic:

The health system factor, in contributing to COVID-19 mortality rate in the first quarter of 2020. However, the positive is also to be seen in this study (Anesi et al., 2021) in the application of a system that enabled rapid…

doi.org/10.7326/M20-53… ..frequent real-time iterative updates in sharing of knowledge btn health carers to recognise ineffective and/or dangerous interventions and where health carers see positive effective measures, in-order to adjust standard operating procedures (SOPs) to improve patient outcomes...
Jan 29, 2021 4 tweets 1 min read
Retrospective analysis:
COVID-19 patients,
n = 91 (aged 74 +/- 13),
2 or more co-morbidities = 54.9%

Given/or not, 400,000 IU vitD
Outcome: transfer to ICU and/or death

The greater the comorbidity burden, the greater effect high-dose vitD treatment mdpi.com/2072-6643/13/1… 39.6% were treated with vitamin D, based on physician decision.

Results showed significant predictive power of four variables, to response to high-dose vitD:

<50 nmol/L, 25(OH)D
current cigarette smoking
elevated D-dimer
presence of comorbid diseases
Jan 24, 2021 18 tweets 3 min read
Viruses always evolve to be more contagious if they can, while at the same time they evolve to being less virulent/pathogenic, especially respiratory viruses. In their evolution, each virus strives to grab “market share” for its progeny. The best way to achieve this is to get host cells in the human body to generate as many copies of itself as possible, while at the same time not make that person so ill that they meet fewer people,