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Landmark Trials Profile picture
Landmark Trials
@LandmarkTrials
Collecting practice-changing clinical trials in Internal Medicine + subspecialties to promote EBM knowledge among medical learners - https://t.co/7oxB3t6Geg
Oct 29, 2022 • 7 tweets • 5 min read
Landmark trial thread🧵

This series of tweets will be about key trials studying SGLT-2 inhibitors in heart failure. While initially studied for DM, these meds were shown to improve CV outcomes in CHF patients, regardless of DM status.

#MedEd #EBM #CardioTwitter #clinicaltrials Image 1) DAPA-HF trial:
Among patients with a reduced EF, the risk of worsening heart failure or death from CV causes was lower among those who received dapagliflozin vs placebo.

Link: nejm.org/doi/full/10.10… ImageImage