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NCI Division of Cancer Biology Profile picture
NCI Division of Cancer Biology
@NCICancerBio
Official Twitter account of the NCI Division of Cancer Biology, funding basic cancer biology research. Privacy policy: https://t.co/47s9FxzVVe
Aug 10, 2021 • 6 tweets • 7 min read
Basic research by Dr. Brian Druker @OHSUKnight in the 1990s contributed to the development of #imatinib (Gleevec), a landmark drug that has improved the outcomes of patients with #chronicmyelogenousleukemia. cancer.gov/research/progr… #NothingWillStopUs Photo of Dr. Brian Druker He discovered that a compound called STI-571 (a.k.a #imatinib) specifically inhibits growth and tumor formation by #leukemia cells expressing BCR-ABL (a fusion oncoprotein that drives #chronicmyelogenousleukemia) in an @theNCI funded @NatureMedicine study. nature.com/articles/nm059…