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Nils Birkholz Profile picture
Nils Birkholz
@NilsBirkholz
Molecular microbiologist investigating bacterial defence systems and mobile genetic elements. Postdoc in the Fineran Lab @Otago. 🇳🇿
Mar 15, 2022 • 12 tweets • 7 min read
Very pleased to share our ✨New Paper✨ about an epigenetic conflict between a restriction–modification system and a methylation-dependent nuclease.

Want to know how that pans out? Continue reading here 🧵👇🏻 or head over to @NAR_Open for the full story: academic.oup.com/nar/advance-ar… It all began when we started investigating the anti-#CRISPR repressor Aca2 from Pectobacterium #phage ZF40. Back then, we stumbled upon an RM system in Pecto that inhibited transformation and conjugation and completely blocked phage infection. 🧬🚫 [2/n]