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Academic Nephrologist, FACP @AZ_Neph 🐻⬇️ • @BookBurton • Interests #electrolytes #kidneystones #uronephrology #onconephrology • Tweets are my own 🌷
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⁉️What is the difference between mineral and organic acidosis?
⁉️Why does one cause more hyperkalemia than the other?
Join me on this 🐇🕳️rabbit hole
on metabolic acidosis and it's effect on potassium.
📊To start, which type of acidosis causes more hyperkalemia?
Metabolic acidosis is defined as a ⬇️low pH due to a ⬇️decrease in bicarbonate extracellularly
💎Mineral acids (aka inorganic acids) are “synthesized from earth minerals.”
🥬Organic acids are metabolized by the cell and occur naturally.
Both can have a 🩸high anion-gap...just depends on anion accumulated.
💎Mineral acids are often (not always) a hyperchloremic normal anion gap metabolic acidosis
Think of 🥬organic acidosis as high anion gap metabolic acidosis (though not always true)
Read 19 tweets
9 Dec 20
🤔🔬Why are kidney stones so interesting?
Because the 🔑tubules > glomeruli
Disagree if you like, but it’s true.
A short thread on some mechanisms associated with calcium stones...
Which is a risk factor for calcium oxalate stones?
Risk factors for calcium oxalate stones classically include 📌hypercalciuria and 📌hyperoxaluria along with 💧low urine volume.
can stem from a LOT of different causes and clinical settings. The most common in adults is idiopathic.
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