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Aug 30, 2023 8 tweets 7 min read
Every company is just trying to "capture value" that's already there.

Our entire society became speculative. Trying to catch the raindrops of trillions of dollars of debt as it 'trickles' down through privileged & nepotistic waterways.

@Uber raised like $25B to reinvent taxis and food delivery. They finally made a profit last quarter after 14Y. Facebook bought instagram just to copy tiktok_us which just copied vine. Then Facebook made threads which is just a copy of Twitter which was made 17y ago. A kid born the day Twitter was made will be able to vote in the next election. AirBnb was supposed to be a way to rent out an extra room or couch, but it just turned into investors buying houses specifically as bed and breakfasts (Without actual breakfasts !). Even the current iteration of #ArtificialIntelligence is just some linear algebra, optimised computing & lots of engineering thrown into the mix. Not much actual innovation.

Long gone are the days when innovation and the desire to build a better world (by actual curious & talented people, not by someone who went to a IvyMBA to get a 5M seed) drove development. The only thing on anyone's mind is how he can make as much money as quickly as possible from something.

#reflections #investment #innovation

1/N "My analysis of start-ups, however, shows that the big losses suf­fered by Uber, Lyft, WeWork, Pinterest, and Snapchat—greater than 50% of revenues annually—are just the tip of the iceberg.

More than 90% of America’s “unicorns”—start-ups valued at $1 bil­lion or more while privately held (before IPOs)—lost money in 2019 or 2020, even though more than half of them were founded over 10Y ago.

And a similar trend of losses holds for European, Indian, and Chinese start-ups.

Of similar importance, recent analyses of venture capital (VC) firms show that ROIs in VCs have barely exceeded those of public stock markets over the past 25Y, and their current losses suggest that returns will fall even further"

Good Lord. IPOs have been strange lately. Lots of unprofitable startups IPO-ing, providing exit liquidity to private investors

"..start-ups that do go public, the % that are unprofitable at the time of their IPO has increased dramatically over the last few decades, exceeding 80% in recent years, according to analysis by Jay Ritter of the University of Florida"

Ref: Rani Molla, “Why Companies Like Lyft and Uber Are Going Public without Having Profits,” Vox, March 6, 2019.



#venturecapital

2/N
Jun 24, 2023 6 tweets 3 min read
This is a real-life story of how corporatisation of #science (MIS complex) has replaced the curious scientists with stronger moral backbones.

James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist, and zoologist. In 1953, he co-authored with Francis Crick the academic paper proposing the double helix structure of the DNA molecule. Watson, Crick and Maurice Wilkins were awarded the 1962 Nobel Prize in Physiology or #Medicine "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material".

1/N
Image Bernadine Patricia Healy (August 4, 1944 – August 6, 2011) was an American cardiologist and the first female director of the National Institutes of Health (NIH).

W. Bush tapped her in 1991 to become director of the NIH, its first woman head.

#science #MISComplex

2/N Image
Jan 11, 2023 24 tweets 13 min read
Considering that modern humans, due to the Neanderthal assimilation (we carry their DNA), are entirely different from the misnamed extinct pre-contact Homo sapiens, it might be time to rename the latter in order to distinguish them from us, maybe as Homo socialis.

1/N Image Since the Neanderthal assimilation most Homo sapiens have retained their predominantly social nature & therefore tend to ostracise those of a predominantly individual nature who, beginning in the 1940s, are being pathologised with the label of #autism

2/N Image
Mar 28, 2022 12 tweets 9 min read
@Mktweets0 Going to start a thread on #melatonin & its effects on CKD validated by scientific research. Please correct if you find any medical faults.

#kidneys @Mktweets0 1/ Melatonin was first purified and characterised from the bovine pineal gland extract by Aron Lerner and co-workers in 1958.

However it has systemic effects. #Kidney cells (proximal tubule) express a melatonin receptor of type MTNR1. pubmed.ncbi.nlm.nih.gov/9034171/
Jan 10, 2022 11 tweets 4 min read
1/ If you can imagine a hunter-gatherer roaming around Africa around 14K years ago, he didn’t know anything about - nation-state, fiat, central bank, corporate law, education, modern markets, industry, pharma, media, politics, modern definition of morality or consumerism Image 2/

Nor they had any concept of money, stock options, CEO of a large organization, boardroom politics, knowledge of vector calculus and abstract mathematics, career struggle, mortgage stress etc.

#lifestyle #simpleliving #career
Sep 18, 2021 7 tweets 5 min read
1/ The Vax$ contains the RNA (encapsulated in liposome) to make one of the spikes found on the outside of the coronavirus. When injected, it is absorbed into a cell and makes one of those spikes on the outside of whatever cell it went in to.

#VaccineMandate #VaccinePassport 2/
The RNA shot was supposed to stay in the arm muscle, making those spikes on the outside of muscle fibres, but instead most of it got flushed into the blood and spread around the body.

#VaccineMandate #VaccinePassport