Excited to share our group's first manuscript describing new anatomical connections that allow the eyes to act as an "immunological window to the brain" 👁️🧠 (1/)

nature.com/articles/s4158… Before we jump in, proud of @XiangyunYin, @zhangsophi and Juhyun for finishing this story --and a heartfelt thank you to @VirusesImmunity, Dean Brown @YaleMed, and the team @YaleOph for their support, guidance, and encouragement that have made all the difference (2/)

Part 2 of SARS-CoV-2 and its effects on the Brain with @ShelFarFar and @VirusesImmunity!

biorxiv.org/content/10.110…
**Highlights**
-Characterization of COVID-19 neuroinflammation
-Indirect evidence of SARS-CoV-2 neuroinvasion
-Evidence of local CNS immunity
#COVID19 #brain 1/n I am especially proud of this story because we not only describe SARS-CoV-2 neuroinflammation, but also used this opportunity to answer several questions about neuroimmunology that was not explored before. 🧠👏 2/n

@VirusesImmunity latest neuro story is up on biorxiv! biorxiv.org/content/10.110…
We used brain organoids, K18-hACE2 mice and our recently described AAV-hACE2 mice to show the neuroinvasive potential of SARS-CoV-2. A huge collaborative effort, so we have a lot to share. Here we go... We started off by infecting some human brain organoids that my classmate Ce Zhang has been growing for the past few years. Check out these beautiful images that he took (more to come). We saw increasing amounts of cells infected over time.