Jonathan H Chen MD PhD Profile picture
Physician Data Scientist - Stanford Center for Biomedical Informatics Research + Division of Hospital Medicine + Clinical Excellence Research Center
Nov 1, 2023 11 tweets 3 min read
Never got around to this, but fulfilling a standard self-congratulatory announcement of my first fully funded NIH R01 grant.
reporter.nih.gov/search/DZYcMKA… Much of this was built off the work of star graduate student @conorkcorbin. Glad to collaborate across sites with @IDInformaticsMD @SanjatKanjilal and with Stanford experts @StephenMaMDPhD @AmyChangMD @StanDeresinski @robtibshirani @steveaschmd and Mary Goldstein
Mar 31, 2023 24 tweets 13 min read
Slides to to engage clinical + informatics communities across multiple forums.

For the two people who have not already heard about and tried using #ChatGPT, over 100 million other people already have. The fastest growing internet application in history. #MedAI Image Good or bad, ready or not, these tools are out there and are being used in all imaginable and some unimaginable ways.
Even LAST quarter, Stanford students are using ChatGPT on the class assignments, including straight up submitting ChatGPT generated answers without any edits. Image
Mar 30, 2023 5 tweets 3 min read
#ChatGPT #AI performance on *open-ended, free-response,* clinical reasoning exams intended for human medical trainees. #LLMs are passing medical licensing exams, but artificial multiple choice designs do not reflect realistic clinical reasoning.
medrxiv.org/content/10.110… From describing diagnostic schema, generating differential diagnoses and problem lists, to suggesting and interpreting tests, ChatGPT is already demonstrating the surprising ability to often reach a 70% passing threshold on multiple cases.
Nov 24, 2022 27 tweets 5 min read
When any given day in academic medicine can feel like a thankless grind on a relentless hamster wheel, it's worth having gratitude for any and all support along the way. 🧵(Image: Belle Kim, Zachary Elgar, and A Prolific Source, 2015) Image As a classical overachiever, it's typical to project a public persona of infallibility and effortless success.
Oct 21, 2018 44 tweets 13 min read
Closing the loop on #Diagnostics #Tweetorial with example #AppleWatch #AFib #Screening. From a company website: "Atrial fibrillation is a silent killer. The heart arrhythmia causes more life-threatening strokes than any other chronic condition, and will affect 1 in 4 of us." "But the sad fact is that atrial fibrillation often goes unnoticed: It is estimated that 40% of those who experience the heart condition are completely unaware of it."
Oct 5, 2018 21 tweets 8 min read
#Tweetorial on #Diagnostics and #Screening interpretation.
An otherwise healthy 40 year old woman comes to you after reading on the internet about a terrible disease that one in a thousand women get, and a highly accurate test that can save her life. The test is over 99% accurate in people with the disease. For those without disease, the test is only wrong 5% of the time.

You order this test and it comes back positive. The woman anxiously asks you, do I have the disease? What is the chance this woman has the disease?