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New York Stem Cell Foundation Research Institute Profile picture
New York Stem Cell Foundation Research Institute
@nyscf
The NYSCF Research Institute is a non-profit organization whose mission is to cure the major diseases of our time through stem cell research.
Mar 25, 2022 • 11 tweets • 9 min read
Drug discovery for complex diseases like #Parkinsons (#PD) is challenging - we need screenable cellular phenotypes to move faster. Today in @NatureComms, we present an #AI-driven phenotyping platform that identifies #PD hallmarks in patient cells: nature.com/articles/s4146… 🧵(1/11) By combining our cell culture #automation, #CellPainting, high-content imaging, and #DeepLearning methods, we built a robust platform for phenotypic profiling and collaborated with @GoogleAI to screen fibroblasts from 91 #Parkinsons patients and matched healthy controls (2/11)