1/
Presidential candidate @RobertKennedyJr came on the @joerogan podcast open.spotify.com/show/4rOoJ6Egr…

Transcript ogjre.com/episode/1999-r…

Lets explore RK Jr's claim: "None of the vaccines are ever subjected to true placebo controlled trials" twitter.com/i/web/status/1… 2/
The point of placebo controlled trials (assuming they're also randomized) is to increase your confidence that any differences in outcomes (e.g. sickness, death) are causally related to the placebo or vaccine - not something else

🛠️⚠️THREAD⚠️🛠️

1/ lets dig into the study @tednaiman shared to support this claim:

it's not evidence-based to recommend a higher-fat version of a low-carb diet **as an option** for patients trying to lose fat

https://twitter.com/tednaiman/status/1637511824282357761

2/ The study wanted "to unravel whether body-weight loss & weight-maintenance depends on the high-protein or the ‘low-carb’ component of the diet"

Obese folks were randomized to 1 of 4 diets

2 weeks = weight-stable run-in phase
3 months = 2/3 kcals cut
9 months = 1/3 kcals cut

1/ Up until September 2020 there are 3-4 mutations on average occurring in sars-cov-2

Coinciding with vaccines introduction, the mutation rate increases to 6-10 & variants of concern emerge

Spike protein is narrowly vaccine targeted & mutating rapidly 2/ synonymous mutation = a DNA change that doesn't change amino acid sequences
nonsynonymous mutation = a DNA change that does

the synonymous-to-nonsynonymous mutation ratio is evidence of selective pressure/adaptive evolution

this appears to be happening with spike protein

#sleep thread

1/ In 2014, a meta-analysis of randomized controlled parallel-group trials comparing placebos to sleep drugs for primary insomnia showed statistically significant small-to-moderate effect size improvements that favored drugs ncbi.nlm.nih.gov/pubmed/25168785 2/ However, the small number of polysomnography studies between 1992 to 2012 were low quality, resulting in “these effects sizes to be non-robust” according to the fail-safe N statistic. If “causal interpretations from non-robust models should be avoided” ncbi.nlm.nih.gov/pubmed/33781862

“Even plant toxins are good for us, via hormesis” 🎭🤮

🚨THREAD🚨

1/ Hormesis is a biphasic adaptive dose-response to a stressor, such as repeated mild heat stress conferring anti-aging benefits to normal human cells in vivo

pubmed.ncbi.nlm.nih.gov/32546350/ &
ncbi.nlm.nih.gov/pmc/articles/P… 2/ The most promising and over-studied polyphenol is resveratrol. It’s a relatively safe compound in most respects [pubmed.ncbi.nlm.nih.gov/20013887/]. It induces hormetic effects via sir2 activation. It extends both lifespan and healthspan of metabolically compromised mammals [...]

🚨Linoleic acid THREAD🚨

- the 45% fat from soybean oil, 55% milk protein diet (HFHP-soy) was 25%⬆️"energy dense" than the other 2

- HFHP-soy had the lowest adiposity index: 33%⬇️than the low-fat high-protein diet & 45%⬇️than the low-fat moderate-protein diet

https://twitter.com/tednaiman/status/1357401781370638341

1/
HFHP-soy had the
- heaviest livers (i'm betting they were fatter)
- least WAT (despite having the most energy dense diet)
- least brown adipose tissue (that "burns fat")
- weighed the least compared to LFHP & LF-mod-protein

1/ Here’s the 3-week *retrospective* RCT mentioned by @foundmyfitness & Dr.Fahey

females drank 600μmol glucoraphanin (GR) + 40μmol sulforaphane (SF) daily, showing no goitrogenic effects or immune responses against it - contrary to what @CarnivoreMD claims

lets jump in

https://twitter.com/foundmyfitness/status/1331727517527404545

2/ in other of Dr.Fahey’s papers he averages GR’s bioavailability to 10%, so lets go with that: 40 SF + (600 GR x 0.1) = 100μmol SF in the drink

100μmol SF/daily didn’t interfere with the thyroid in 26 women (TSH, fT4, TG TPO- & TG-antibodies), 45 if you add placebo group

1/

Fuck me

1.88M views for "A Mom Tried Keto Diet For 30 Days. This Is What Happened When Things Went Wrong"

"Based on the comments, an incredible amount of people missed what actually happened here... 2/ "She had a tumor in her pancreas that caused a chronically elevated level of insulin, which was constantly pushing her blood sugar below the normal range. Going keto forced her body to rely entirely on the glucose it produces itself, which your body is normally able to do..."

1/ Here’s this week’s @Nutrita_app #science email. Sign up for them at nutrita.app

“You’ve heard it before, fat will make you fat. It’s calorie dense and tasty. End of story.

Wrong. Although fat is calorie dense and fat is tasty, it doesn’t make you fat per se. 2/ “It’s not enough - overfeeding studies make this crystal clear [pubmed.ncbi.nlm.nih.gov/7369169/ & pubmed.ncbi.nlm.nih.gov/1414963/]. However, it’s true that some fats are more fattening than others (on a per calorie basis). See our Good fats, Bad fats article for more nutrita.app/good-fats-vs-b…

1/ i finished going over the 3 studies @gerdosi linked to as evidence *against* restricting n6 fats for #COVID19

https://twitter.com/gerdosi/status/1268535021931028481?s=20

@TuckerGoodrich @puddleg @Ken__Strain @FatEmperor @maximumcharacte @fmahmad88 @stevenhamley @gfj1979 @siobhan_huggins 2/ the in vitro study does indeed show, as you say, that LA strongly inhibits viral replication and thus strongly drops viral load. the caveat being that this occurs at non-physiological levels that are x2-5 higher than plasma values (per my back of the envelope estimation)