'Mitochondrial alterations in NK lymphocytes from ME/CFS patients' published in The Journal of Immunology. #pwME #MyalgicE #MedEd #MEcfs #health #research
#ScienceNotStigma #GPnews
jimmunol.org/content/202/1_…
"ME/CFS patients have impaired natural killer (NK) cell activity. NK lymphocytes are a critical first defense against viruses and cancer. ME/CFS patients have difficulties controlling viral infections and many develop non-Hodgkin’s lymphoma."
"In our study, we observed that the two main energy-generating mitochondrial pathways, oxidative phosphorylation and glycolysis (bioenergetics parameters), are deregulated in ME/CFS NK cells and in peripheral blood mononuclear cells (PBMCs)."
"These mitochondrial features can affect NK cell function and contribute to the severity of disease. To date, this is the first metabolism assessment of NK cells in ME/CFS and as potential new diagnostic tool for the disease."
Seems like a good place to share @MEAssociation's latest summary of the role of mitochondria in ME/CFS:
meassociation.org.uk/2019/07/mea-su…
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