Prof Chris P Gale Profile picture
Professor of Cardiovascular Medicine, Honorary Consultant Cardiologist. Specialist adult cardiovascular care: putting research into practice to benefit patients

Jul 24, 2020, 13 tweets

Sex-differences in mortality rates & underlying conditions for #COVID19UK deaths in England & Wales mayoclinicproceedings.org/article/S0025-…

Limited national data exists about the prevalence & distribution of underlying conditions among COVID-19 deaths between sexes & across age groups.

We studied all adult (≥18 years) deaths recorded in England & Wales between 1st March 2020 & 12th May 2020.

We compared the prevalence of underlying health conditions between #COVID19 and non-COVID19 related deaths during the pandemic.

We also compared the age-standardized mortality rate (ASMR) of #COVID19 with other primary causes of death, stratified by sex & age group.

Of the 144,279 adult deaths recorded during the study period, 36,438 (25.3%) were confirmed #COVID19 cases.

Women represented 43.2% (n=15,731) of the #COVID19 deaths compared with 51.9% (n=55,980) in non-COVID19 deaths.

Overall, COVID deaths were younger than non-COVID deaths (82 vs. 83 years).

The ASMR of #COVID19 was higher than all other common primary causes of death, across age groups & sexes, except for cancers in women between the ages of 30-79 years.

A linear relationship was observed between ASMR & age amongst #COVID19 deaths, with persistently higher rates in men than women across all age groups.

The most prevalent reported conditions were #hypertension, #dementia, chronic lung disease & #diabetes, and these were higher amongst COVID19 deaths.

Pre-existing ischemic heart disease was similar among #COVID19 (11.4%) and non-COVID19 (12%) deaths.

... the first nationwide (full adult populace) study of causes of death & underlying medical conditions during the #Covid_19 pandemic led by @mmamas1973 & @dr_mosama with @dataevan @TomLuscher et al. mayoclinicproceedings.org/article/S0025-…

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