Let’s talk about #Immunity and #COVID19! In the narrative of an army and enemy.
Our immune system is like an army. Its mission? To protect us from enemies both foreign (viruses and bacteria) and domestic (diseases like cancer).
When the enemy (#SARSCoV2 for COVID19).. 1/n
..enters our body, our army’s first line of defence with army’s surveillance officer (helper T-Cells) are pressed into action. The enemy (viruses) can enter cells by infecting cells directly, leading to replication of virus inside the cells. During this process, 2/n
some of the viral proteins (enemy’s target body parts, usually the brain or heart is better for one-go kill) will be degraded into peptide fragments, which will be recognized by the army’s surveillance officer (presented on these helper T-Cells). 3/n
Through a series of events from priming to eventually getting readied, now our army’s men and women with the artillery guns (Killer T-Cells) will fire bullets (cytotoxic granules) and kill the enemy. This process is short and can clear the enemy army (virus) effectively ..4/n
.. without much noise (symptoms). Now, in case, the enemy survives this artillery gunners (T-Cell), then it has overwhelmed our primary resources (now minor symptoms will appear), but it has not yet reached the parliament. At this point, the second command .. 5/n
.. with tanks and bombers (B-Cells) are sent to the rescue mission. Once activated, initially these tanks (B-Cells) will fire heavy ammunitions (short lasting IgM) and once, this short lasting ammunitions are exhausted, it will fire the bigger missiles and ..6/n
.ammunitions (long lasting IgG) to clear the enemy from our body. At this stage, our artillery gunners (T-Cells) are also providing cover firing support (releasing cytokine) to tanks and bombers (B-Cells). At this stage, the war is full blown!! Now, ..7/n
.. due to lack of proper coordination between artillery gunners and tanks (T-Cells and B-Cells) due to higher number of enemy's army (*high viral load), there is leak of false information (bad cytokines) and at this point, our army fails to recognize the enemy and ..8/n
.. starts shooting our own body’ cells (cytokine storm). This type of poor coordination between various wings of the army (T-Cell and B-Cell) is seen in elderly population and people deficient of #vitaminD , and other essential vitamins/minerals. 9/n
No wonder, people of all ages are succumbing to this common enemy, more often the elderly. In children though, as recently their army were trained (by multiple dosage of vaccines), they don’t misfire and their army is well regulated, thanks to the training !! 10/n
*Masks help in reducing the number of enemies (high viral load). END 🙏🙏
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