Let's take a look at the data from the @CDCgov ACIP meeting last week on #COVID19 #vaccine safety in #pregnancy.
It continues to be reassuring!
First, let's take a look at the new data from the V-safe pregnancy registry... 🧵
cdc.gov/vaccines/acip/…
As of the 13th September, the registry contained 5096 participants. 2/
After they have joined, the participants are interviewed in every trimester, shortly after giving birth, and again when their babies are more than three months old. 3/
First, they go through the data showing that, among 2456 people vaccinated before 20 weeks, the risk of miscarriage was normal.
This has been recently published and you can read about it in more detail here... 4/
But there is one additional graphic that is quite nice. This compares the week-by-week miscarriage rate in those who received the COVID vaccine, vs two studies of miscarriage rates from before the pandemic.
You can see that post-vax miscarriage rates are bang in the middle. 5/
The next section looks at outcomes for babies at birth.
The registry contains 1634 live born babies. 70% born following 3rd trimester vaccination and 30% following second trimester vaccination. 6/
Among these babies, the rates of preterm birth, being small for gestational age, admission to neonatal intensive care and infant death are all normal. 7/
45 babies had a birth defect. The types and rates of birth defects were consistent with what is usually seen in the USA. So no evidence of an increased risk of birth defects following vaccination in this cohort. 8/
That's all from the V-safe pregnancy registry! I'm off to do the school run now, but I'll be back later with an update from the Vaccine Safety Datalink... 9/9
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