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Dan Wyke 🦠➡️🧠🔥 Profile picture
@Dan_Wyke
Oct 13, 2019 • 3 tweets • 4 min read • Read on X
Review protocols so 'robust' That Cochrane continues to endorse graded exercise therapy as a treatment for ME even though the decision is based on extremely poor quality research and flies in the face of the experience of millions ME sufferers. #pwME #MyalgicE #StopGET #MEcfs
Cochrane’s decision also ignores more and more research like this demonstrating the negative effect exercise has on ME. #pwME #MyalgicE #ScienceNotStigma #MedEd #MEcfs #health #GPnews
healthrising.org/blog/2019/10/1…
Are Cochrane’s editors unduly influenced by the authors of the flawed research? How else can their decision to defend research that's dismissed by academics around the world be explained? How can they ignore the mounting evidence that shows exercise harms people with ME?

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More from @Dan_Wyke

Dan Wyke 🦠➡️🧠🔥 Profile picture
Dec 28, 2025
🧵 PART 2: A selection of #MECFS and #LongCovid research papers published in 2025 contd:

26/ 'AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome' nature.com/articles/s4159…
27/ 'Heightened innate immunity may trigger chronic inflammation, fatigue and post-exertional malaise in ME/CFS' medrxiv.org/content/10.110…
28/ 'Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19' frontiersin.org/journals/neuro…
Read 14 tweets
Dan Wyke 🦠➡️🧠🔥 Profile picture
Dec 28, 2025
🧵 A selection of #MECFS and #LongCovid research papers published in 2025:

1/ 'Abnormal T-Cell Activation And Cytotoxic T-Cell Frequency Discriminates Symptom Severity In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome'
medrxiv.org/content/10.110…
2/ 'Re-visiting professional ethics in psychotherapy: reflections on the use of talking therapies as a supportive adjunct for ME/CFS and "medically unexplained symptoms" (MUS)' jme.bmj.com/content/early/…
3/ "ME/CFS is a diagnosable sequela that develops at an increased rate following SARS-CoV-2 infection." #MyalgicEncephalomyelitis #MECFS link.springer.com/article/10.100…
Read 25 tweets
Dan Wyke 🦠➡️🧠🔥 Profile picture
Mar 31, 2025
🧵 1/8 Continuing her impressive work with AI, @JennyWi04810918 asked ChatGPT to devise a treatment plan based on "all the confirmed published research that has been replicated in M.E., starting from 1955 to the present day." Here's what it came up with... Image
2/8 Image
3/8 Image
Read 8 tweets
Dan Wyke 🦠➡️🧠🔥 Profile picture
Mar 30, 2025
🧵1/11 Jenny Wilson (@JennyWi04810918) is obtaining some fascinating results using AI to interpret test results of anonymous, severely ill #MyalgicEncephalomyelitis patients who have been dismissed by their GP. In this case, Jenny didn't mention ME.

Here's what ChatGPT said: Image
2/11 Image
3/11 Image
Read 11 tweets
Dan Wyke 🦠➡️🧠🔥 Profile picture
Dec 20, 2024
🧵 A selection of #MECFS and #LongCovid research papers published in 2024:

1/ 'Physical exertion worsens symptoms in patients with post-COVID condition : Post-exertional malaise in patients with post-COVID condition'
scienceopen.com/hosted-documen…
2/ 'Muscle abnormalities worsen after post-exertional malaise in long COVID'
nature.com/articles/s4146…
3/ 'Dysregulation of extracellular vesicle protein cargo in female myalgic encephalomyelitis/chronic fatigue syndrome cases and sedentary controls in response to maximal exercise'
isevjournals.onlinelibrary.wiley.com/doi/10.1002/je…
Read 22 tweets
Dan Wyke 🦠➡️🧠🔥 Profile picture
Apr 13, 2024
Short 🧵

The medical community is failing #pwME badly right now. From GPs who deny patients medication for treatable symptoms to consultants who deny appropriate feeding arrangements for severely ill patients in hospital. 1/4 #MECFS #MyalgicEncephalomyelitis
Change is being blocked by bad faith actors who occupy positions of strategic importance in the medical hierarchy. The new NICE guidelines only seem to have reinforced their determination to retain the fallacious biopsychosocial model of #MECFS in the healthcare system. 2/4
This is undoubtedly a low point for the #MECFS patient community. Even somewhat better media coverage hasn't budged the dial. Ideally we would take visible direct action, but since that isn't possible, we must continue to speak out against the prejudice and maltreatment. 3/4
Read 4 tweets

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