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Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
@celinegounder
Jan 27, 2020 • 11 tweets • 9 min read • Read on X
Big developments re: #Wuhan #nCoV2019 #coronavirus outbreak in China since Friday. It looks like the virus has been spreading since November, maybe even October, and may not have started at the Wuhan market. thelancet.com/journals/lance…
This means that the virus may have already spread more widely in the region than we'd realized... just under the radar. Now that our radar is up, and we're looking and testing for #coronavirus cases, we may be picking them up.
So the dramatic increase in cases over the last couple days not actually be as sudden as it seems... but something that's been building up over months.
It's hard to find a needle in a haystack when the haystack is big. It's cough/cold/flu season. The symptoms of the #coronavirus are the same. So it's tough to pick up a #NovelCoronavirus outbreak in the middle of that.
Lesson 3 from the #Ebola epidemic for the #Wuhan #nCoV2019 #coronavirus outbreak: Signal-to-noise. It was hard to differentiate #Ebola patients from those with fever from run-of-the-mill malaria, typhoid, and other fever-causing diseases in the region.
When you're looking for a needle (in this case, the #Wuhan #nCoV2019 #coronavirus) in a haystack, anything you can do to reduce the size of the haystack helps! Please get your #influenza #flu #flushot. Wash your hands. Cover your mouth with your elbow when you cough/sneeze. Image
The other big news: the Chinese health minister says the #Wuhan #nCoV2019 #coronavirus might be spread by infected persons without symptoms. This would be a gamechanger. businessinsider.com/coronavirus-ca…
Note that whether #Wuhan #nCoV2019 #coronavirus might be transmitted by asymptomatic persons has yet to be confirmed by @CDCgov scientists. But *if* true, this is scary.
@CDCgov When we don't have drugs/vaccines for a disease, we rely on the basics: identify cases by screening for symptoms & testing for disease and conduct contact-tracing. But case-finding and contact-tracing rely on looking for symptoms.
@CDCgov I really hope the #wuhan #nCoV19 #coronavirus isn't transmitted by asymptomatic persons.
@CDCgov More on the #Wuhan #nCoV19 #coronavirus: bloomberg.com/news/videos/20…

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More from @celinegounder

Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Nov 17
1/ I explain how RFK Jr's plans could affect Americans' health.

He is known for falsely claiming that vaccines cause autism & other health issues.

cbsnews.com/video/doctor-e…
2/ RFK Jr: "The problem with the measles vaccine is that it's a leaky vaccine. It doesn't provide sterilizing immunity."

It's true that the measles vaccine doesn't prevent ALL infections.

It's ~97% effective after 2 doses.
3/ In rare cases, vaccinated people may get infected & transmit the virus to others.

This is all the more reason for vaccinating everyone in a community, not just those who feel like it.
Read 13 tweets
Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Nov 16
1/ RFK Jr. to lead @HHSGov US Dept of Health & Human Services

with @AdrianaDiaz & @tonydokoupil on @CBSMornings
2/ Kennedy has criticized multiple public health agencies he could now lead.

He's said the @US_FDA's "war on public health is about to end," claiming the agency suppresses anything that "advances human health & can't be patented" by pharmaceutical companies.
3/ But Kennedy's statement demonstrates a common misunderstanding about public health authorities in te US.

We are the United States of America — public health powers reside at the state level.
Read 23 tweets
Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Sep 19
1/ A new report from the American Association for Cancer Research @AACR finds that excessive alcohol use is a risk factor for at least 6 cancers.

with @GayleKing @vladduthiersCBS @tonydokoupil
2/ Heavy drinking is associated with an increased risk of:
🔹head & neck cancer
🔹esophageal cancer
🔹stomach cancer
🔹liver cancer
🔹colorectal cancer
🔹breast cancer Image
3/ Drinking during pregnancy can also increase the risk of leukemia later in childhood.

At least 5% of cancers are attributable to alcohol.
Read 19 tweets
Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Aug 15
1/ Yesterday, the @WHO declared mpox a public health emergency of international concern (PHEIC).

This is the 2nd time in 2 years that the WHO has declared a PHEIC for mpox.

with @vladduthiersCBS on @CBSMornings
2/ There have already been more than 17K cases in Africa so far this year – more than the total for all of last year.
3/ @WHO announces a Public Health Emergency of International Concern (PHEIC) when there is a significant risk to global health & it requires an internationally coordinated response.

A PHEIC:
🔹helps marshal funding for a public health response
🔹pressures governments to act
Read 22 tweets
Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Jul 27
1/ COVID study shows mask and vaccine mandates saved lives

with @CBSNews' @LanaZak cbsnews.com/video/covid-st…
Image
2/ A new study published in the JAMA Health Forum yesterday found that:
🔹mask requirements & vaccine mandates were associated with ⬇️ deaths
🔹prohibitions on vaccine or mask mandates were associated with ⬆️death rates

jamanetwork.com/journals/jama-…
3/ Activity limitations (e.g. closing schools, restaurants, bars; stay-at-home orders; restrictions on leisure time activities & public gatherings) likely provided minimal benefit while imposing substantial cost.
Read 6 tweets
Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Jul 26
1/ New Hope Against Dementia: study says singles vaccine also appears to delay onset of dementia
with @CBSMornings' @tonydokoupil @AdrianaDiaz @nateburleson
2/ A study published yesterday in Nature Medicine found that the new Shingrix vaccine was more protective than the old Zostavax vaccine in delaying dementia.

The Zostavax shingles vaccine was discontinued after the Shingrix vaccine was approved.

nature.com/articles/s4159…Image
3/ The Shingrix vaccine is also more protective than Zostavax in preventing shingles.

Shingles is caused by the varicella-zoster virus (VZV), a herpes virus that also causes chickenpox.
Read 15 tweets

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