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Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
@celinegounder
Jan 27, 2020 • 11 tweets • 9 min read • Read on X
Big developments re: #Wuhan #nCoV2019 #coronavirus outbreak in China since Friday. It looks like the virus has been spreading since November, maybe even October, and may not have started at the Wuhan market. thelancet.com/journals/lance…
This means that the virus may have already spread more widely in the region than we'd realized... just under the radar. Now that our radar is up, and we're looking and testing for #coronavirus cases, we may be picking them up.
So the dramatic increase in cases over the last couple days not actually be as sudden as it seems... but something that's been building up over months.
It's hard to find a needle in a haystack when the haystack is big. It's cough/cold/flu season. The symptoms of the #coronavirus are the same. So it's tough to pick up a #NovelCoronavirus outbreak in the middle of that.
Lesson 3 from the #Ebola epidemic for the #Wuhan #nCoV2019 #coronavirus outbreak: Signal-to-noise. It was hard to differentiate #Ebola patients from those with fever from run-of-the-mill malaria, typhoid, and other fever-causing diseases in the region.
When you're looking for a needle (in this case, the #Wuhan #nCoV2019 #coronavirus) in a haystack, anything you can do to reduce the size of the haystack helps! Please get your #influenza #flu #flushot. Wash your hands. Cover your mouth with your elbow when you cough/sneeze. Image
The other big news: the Chinese health minister says the #Wuhan #nCoV2019 #coronavirus might be spread by infected persons without symptoms. This would be a gamechanger. businessinsider.com/coronavirus-ca…
Note that whether #Wuhan #nCoV2019 #coronavirus might be transmitted by asymptomatic persons has yet to be confirmed by @CDCgov scientists. But *if* true, this is scary.
@CDCgov When we don't have drugs/vaccines for a disease, we rely on the basics: identify cases by screening for symptoms & testing for disease and conduct contact-tracing. But case-finding and contact-tracing rely on looking for symptoms.
@CDCgov I really hope the #wuhan #nCoV19 #coronavirus isn't transmitted by asymptomatic persons.
@CDCgov More on the #Wuhan #nCoV19 #coronavirus: bloomberg.com/news/videos/20…

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More from @celinegounder

Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Apr 9
1/ My colleague @DrLaPook's interview with @HHSGov @SecKennedy raised critical questions about public health, vaccines & government responsibility.

on @CBSMornings
2/ RFK Jr, a longtime vaccine skeptic, now recommends the measles vaccine during an outbreak.

This is a significant shift, but his statements on vaccine safety testing need clarification.
3/ Vaccines undergo rigorous testing in Phase 3 & 4 clinical trials, often lasting years to decades.

Claims that vaccines are tested for only "3-4 days" without placebos are misleading.
Read 16 tweets
Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Mar 21
1/ Billions of dollars in @NIH medical research at risk amid Trump cuts
with @jdickerson on @CBSEveningNews
cbsnews.com/video/billions…Image
2/ The total @NIH budget is $48.6B.

It's hard to say how much will be cut in total as the cuts are still in progress, but BILLIONS of dollars will be cut.
3/ This is in addition to NIH dollars that have been held up by delays in approval processes.

If universities can't make payroll, they can't hire & have to let people go.
Read 32 tweets
Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Mar 7
1/ A lesser-known fact about measles is how the virus can damage the immune system, leaving someone at greater risk of other infections even after a person has recovered.
with @nateburleson @GayleKing @AdrianaDiaz on @CBSMornings

It's called MEASLES IMMUNE AMNESIA.
pmc.ncbi.nlm.nih.gov/articles/PMC85…
2/ Let’s say you have 2 babies.

As they grow, their immune systems mature & they both gain immunity to different infections – as represented by the different colored marbles. Image
3/ One baby gets vaccinated against measles at age 1 & later at age 4.

It's recommended that babies get their 1st dose at 12-15 months (when antibodies from mom fade away) & 2nd dose at 4-6 years (when kids start school). Image
Read 12 tweets
Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Nov 17, 2024
1/ I explain how RFK Jr's plans could affect Americans' health.

He is known for falsely claiming that vaccines cause autism & other health issues.

cbsnews.com/video/doctor-e…
2/ RFK Jr: "The problem with the measles vaccine is that it's a leaky vaccine. It doesn't provide sterilizing immunity."

It's true that the measles vaccine doesn't prevent ALL infections.

It's ~97% effective after 2 doses.
3/ In rare cases, vaccinated people may get infected & transmit the virus to others.

This is all the more reason for vaccinating everyone in a community, not just those who feel like it.
Read 13 tweets
Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Nov 16, 2024
1/ RFK Jr. to lead @HHSGov US Dept of Health & Human Services

with @AdrianaDiaz & @tonydokoupil on @CBSMornings
2/ Kennedy has criticized multiple public health agencies he could now lead.

He's said the @US_FDA's "war on public health is about to end," claiming the agency suppresses anything that "advances human health & can't be patented" by pharmaceutical companies.
3/ But Kennedy's statement demonstrates a common misunderstanding about public health authorities in te US.

We are the United States of America — public health powers reside at the state level.
Read 23 tweets
Céline Gounder, MD, ScM, FIDSA 🇺🇦 Profile picture
Sep 19, 2024
1/ A new report from the American Association for Cancer Research @AACR finds that excessive alcohol use is a risk factor for at least 6 cancers.

with @GayleKing @vladduthiersCBS @tonydokoupil
2/ Heavy drinking is associated with an increased risk of:
🔹head & neck cancer
🔹esophageal cancer
🔹stomach cancer
🔹liver cancer
🔹colorectal cancer
🔹breast cancer Image
3/ Drinking during pregnancy can also increase the risk of leukemia later in childhood.

At least 5% of cancers are attributable to alcohol.
Read 19 tweets

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