The maximum plasma concentration reached with that dose is around 40 ng/ml.
That is 50-fold less that the concentration proven to cut viral replication in half.
There is however hope. Prove antiviral activity opens the door to carefully conducted and controlled trials.
Now, if you are considering using ivermectin on a compassionate basis you must know this:
Ivermectin can cross react with GABA-gated chlorine channels in the CNS and cause neurotoxicity. This is normally prevented by the blood bran barrier (BBB), particularly by the P-gp.
If you do not have a fully functional BBB ivermectin may not be the safe drug it usually is.
Now, hyperimflammatory states, such as the one caused by #COVID19 make the BBB leaky.
I would be careful to use ivermectin in severely ill patients with proven efficacy.
Additionally, please be careful with drug-drug interactions.
Many #COVID19 patients are receiving Lopinavir/Ritonavir.
Rito is a very good CYP3A4 inhibitor with some effect on the P-gp as well.
It can boost ivermectin increasing Cmax and potentially penetration on the CNS.
"People should never take animal drugs, as the FDA has only evaluated their safety and effectiveness in the particular animal species for which they are labeled. These animal drugs can cause serious harm in people"
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I have been working with ivermectin since 2008. This includes animal models, insectary work and clinical trials.
Here is one of my earliest experiences with it. A girl with disseminate strongyloides in rural Venezuela.