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Clarity on Hydroxychloroquine and Azithromycin.
Below are the list of trials that show any convincing evidence of safety and efficacy.
Despite @POTUS's assertion and strong testimonial, and his blocking Tony Fauci's ability to respond to the question at today's press conference
The clip, if you missed it, blocking Fauci.
We will know soon in the weeks ahead about these drugs as there is extensive testing ongoing. There are serious side effects; they are NOT approved by @US_FDA, as asserted, for this purpose
Adding Dr. Faust's wisdom from earlier today. 🙏 Jeremy
Add this accurate coverage on the topic
nytimes.com/2020/04/05/us/…
by @michaelcrowley @katie_thomas @maggieNYT
My "go to" for drug effects is @DerekLowe. Today he summarized the latest data on this controversy
blogs.sciencemag.org/pipeline/archi… @ScienceMagazine
"statistically, it's like a funhouse mirror"
Cliff notes here:
And the expression of concern by the journal about the most frequently cited H + A paper is of concern
isac.world/news-and-publi…
retractionwatch.com/2020/04/06/hyd…
via @RetractionWatch @ivanoransky @armarcus
May not be the best evidence base
"Fox host Laura Ingraham & two doctors who are regular on-air guests ...visited the White House last Friday for a private meeting w/ Trump to talk up the drug.."
washingtonpost.com/politics/what-…
@PhilipRucker @lauriemcginley2 @costareports @jdawsey1
Prior @US_FDA commissioners and review of new data argue against the use of these drugs without proper testing
sciencemag.org/news/2020/04/f… by @cpiller @ScienceMagazine
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Eric Topol
@EricTopol
How does April 9 look for US deaths?
—The US is about to take over the cumulative curve, exceeding 20,000 deaths, and that of Italy and Spain
—For the 7-day rolling average, US soon to go over the top, may require a new Y-axis (hopefully not)
@FT #dataviz from @jburnmurdoch
Here's @TheEconomist curve from earlier today:
To get to the current estimate of ~60,000 deaths in the US it will require a lot more flattening. Right now we are still at a 3+ day doubling time economist.com/news/2020/03/1…
npr.org/2020/04/09/830…
Same for the US @nytgraphics @UpshotNYT
But encouraging, at right, is to see such consistent flattening across the hard-hit US states, reflecting their mitigation efforts
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Eric Topol
@EricTopol
Yes. Masks for the public. "as with parachutes for jumping out of airplanes, it is time to act without waiting for randomized controlled trials evidence"
bmj.com/content/369/bm… @bmj_latest by @trishgreenhalgh and colleagues #Masks4All
It's no longer "Should you?"
Just do it. Period.
economist.com/science-and-te…
@TheEconomist #Masks4All
In spite of this week's @WHO's guidance
Read 3 tweets
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Eric Topol
@EricTopol
I had missed this terrific review on #COVID19 vaccine prospects by @FatimaAmanat & @florian_krammer @ImmunityCP cell.com/immunity/pdf/S… @IcahnMountSinai @IcahnInstitute @SinaiImmunol
via @dlammerts
A key point: it'll take longer than many of us hoped or had been led to believe
An effective drug for treatment, especially a repurposed one, is likely to be much sooner theatlantic.com/science/archiv…, by @sarahzhang, @TheAtlantic reviewing the different ways drugs can attack the virus
The good things about drugs is that there are so many shots on goal, and they're summarized remarkably well this week by @jbrafel here👇
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